United States · Investor

5AM Ventures

Last cheque observed Oct 2026; 147 cheques on record.

Deploying nowNew fund $285M, Mar 2021VC firm

SeedSeries ASeries BBiopharmaceuticalsBiotechnologyDrug_delivery

Deploying now
69%of best year9cheques in 12 months, 147 on record
Since the last cheque12days00hrs00min00sec
Median round$55MCheque size, as they say$100K – $5.0MRounds led0 of 147Sole investor13 roundsExits10 from the portfolioMostly inUnited States, 92%
Pitch 5AM Ventures

5AM Ventures highlights

  1. 01

    9 cheques in the last 12 months

  2. 02

    Mostly Series A and Series B: 62% of its rounds

  3. 03

    Sole investor in 13 rounds, median $13M

  4. 04

    10 exits from the portfolio

What they do

We’re a life science venture capital firm founded in 2002.From their own website
Type
VC firm (from a list, unverified)
Cheque size
$100K – $5.0M as they say
Stages
SeedSeries ASeries BGrowthPre-IPO
Sectors
BiopharmaceuticalsBiotechnologyDrug_delivery
Based in
San Francisco, United States
Cold pitches
Not stated

The record

Every round we can evidence, newest first147 appearances

  1. 2026

    7 rounds

  2. Oct
    NouscomSeries D · CH · Revelation Partners$135MWith 14 others
  3. Jun
    IDEAYA BiosciencesUS$345MWith 3 others
  4. Jun
    Enliven TherapeuticsUS$460MWith 3 others
  5. Jan
    MendraSeries A · US$82MWith 4 others
  6. Jan
    Precede BiosciencesSeries B · US$64MWith 2 others
  7. Jan
    Kinaset TherapeuticsSeries B · US$103MWith 3 others
  8. Jan
    Spruce BiosciencesVenture · USUndisclosedWith 3 others
  9. 2025

    9 rounds

  10. Dec
    ProLynxSeries A · US$70MWith 3 others
  11. Nov
    Lifordi ImmunotherapeuticsVenture · US$42MWith 3 others
  12. Jul
    MapLight TherapeuticsSeries D · US · Avego Management$373MWith 8 others
  13. Jul
    Fellow HealthSeries B · US$24MWith 2 others
  14. Jul
    Renasant BioSeed · US$55MWith 3 others
  15. May
    GlycoEraSeries B · CH · TechStartups$130MWith 8 others
  16. Mar
    Latigo BiotherapeuticsSeries B · US$150MWith 4 others
  17. Mar
    SurrozenUS$175MWith 3 others
  18. Feb
    Tectonic TherapeuticUS$185MWith 2 others
  19. 2024

    12 rounds

  20. Sept
    Deverra TherapeuticsCrowdfunding · US$972KSole investor
  21. Aug
    scPharmaceuticalsDebt · US$125MWith 3 others
  22. Jul
    Magnetic InsightVenture · USUndisclosedWith 4 others
  23. Jul
    IDEAYA BiosciencesUS$263MWith 3 others
  24. Jul
    TMRW Life SciencesSeries D · US$28MWith 3 others
  25. Jun
    RareCyteVenture · US$20MSole investor
  26. Jun
    Entrada TherapeuticsUS$100MWith 6 others
  27. May
    KariusSeries C · US$100MWith 6 others
  28. May
    BiozVenture · USUndisclosedWith 2 others
  29. Apr
    RallybioUS$6.6MWith 2 others
  30. Mar
    NouscomSeries C · CH$7.6MWith 4 others
  31. Jan
    Skye BioscienceUS$50MSole investor
  32. 2023

    5 rounds

  33. Nov
    HalioVenture · US$70MWith 3 others
  34. Sept
    Nvelop TherapeuticsSeed · US$100MWith 1 other
  35. Aug
    Radionetics OncologySeries A · US$53MWith 1 other
  36. May
    Nido BiosciencesSeries B · US$87MWith 2 others
  37. Jan
    Expansion TherapeuticsVenture · US$6.9MWith 4 others
  38. 2022

    4 rounds

  39. Nov
    Escient PharmaceuticalsSeries C · US$120MWith 4 others
  40. Sept
    Novome BiotechnologiesSeries B · US$44MWith 4 others
  41. Aug
    CinCor PharmaUS$225MWith 7 others
  42. Apr
    Portal InstrumentsVenture · US$7.0MWith 1 other
  43. 2021

    4 rounds

  44. Dec
    Pear TherapeuticsUS$125MWith 5 others
  45. Aug
    NeurogastrxSeries B · US$60MWith 4 others
  46. May
    Soteria BiotherapeuticsSeries A$42MWith 2 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

The team

Named by the firm itself, on a filing, its Form ADV or its company registration6 named

AJAndrew James SchwabMember, 5Am Venture Management LLCiForm ADV
JDJohn David DiekmanExecutive OfficeriFiling they signed
KMKush M. ParmarMember, 5Am Venture Management, LLCiForm ADV
LALauren Alison DanielChief Compliance OfficeriForm ADV
PAPaul A StonePartner, Chief Legal OfficeriForm ADV
SMScott Michael RocklageExecutive OfficeriFiling they signed

We also hold 39 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

What the register says

From the firm's own filings with the SEC, which it must file accurately by law

$1.1Bassets it managesOct 2026
5+funds on filenumbered funds in its name
Registeredinvestment adviserfull reporting to the SEC
Legal name
5am Venture Management, LLC
SEC number
CRD 160395

Funds on its Form ADV

11 private funds, $1.5B in gross assets · filed Nov 2024

Venture 9Private equity 2

  1. 5AM Ventures VII, L.P.Venture106 investors$413M
  2. 5AM Ventures VI, L.P.Venture87 investors$376M
  3. 5AM Opportunities II, L.P.Private equity86 investors$320M
  4. 5AM Ventures V, L.P.Venture81 investors$150M
  5. 5AM Ventures IV, L.P.Venture50 investors$82M
  6. 5AM Opportunities I, L.P.Private equity49 investors$68M
  7. 5AM Ventures II, L.P.Venture45 investors$27M
  8. 5AM Ventures III, L.P.Venture45 investors$14M
  9. 5AM Co-Investors IV, L.P.Venture33 investors$3.4M
  10. 5AM Co-Investors II, L.P.Venture31 investors$1.1M

And 1 more on the filing.

Exits from the portfolio

Companies it backed that were later bought or listed10 in all

Novira TherapeuticsBought by Johnson & JohnsonUndisclosedNov 2015
CalibriumBought by Novo NordiskUndisclosedAug 2015
IkariaBought by Mallinckrodt$2.3BMar 2015
DVS SciencesBought by Fluidigm$208MJan 2014
Pearl TherapeuticsBought by AstraZeneca$1.1BJun 2013
KaloBios PharmaceuticalsListedUndisclosedJan 2013
Incline TherapeuticsBought by The Medicines CompanyUndisclosedDec 2012
Semprus BioSciencesBought by Teleflex$30MJun 2012
Synosia TherapeuticsBought by Biotie Therapies$122MJan 2011
Marcadia BiotechBought by RocheUndisclosedDec 2010

An exit counts when it came after the firm's first round in the company. From historical deal records.

Who they invest alongside

The investors most often in the same rounds as 5AM Ventures. A count of rooms they were both in, not a relationship either has claimed.

Recently backed

The latest companies 5AM Ventures put money into.

Quick answers about 5AM Ventures

What does 5AM Ventures invest in?

5AM Ventures invests most often at Series A and Series B (62% of the rounds on record), in sectors such as Biopharmaceuticals, Biotechnology and Drug_delivery.

How active is 5AM Ventures?

147 investments on record, 9 of them in the last 12 months. The most recent was in Oct 2026.

What has 5AM Ventures invested in recently?

Its most recent investments on record: Nouscom (Series D, Oct 2026), IDEAYA Biosciences (Undisclosed round, Jun 2026) and Enliven Therapeutics (Undisclosed round, Jun 2026).

How big are 5AM Ventures's cheques?

The median round it joins is $55M. It says it writes cheques of $100K to $5.0M.

Does 5AM Ventures lead rounds?

Rarely, if at all: none of its 147 investments on record names it as the lead.

Where does 5AM Ventures invest?

Most of the companies it backs are in the United States (92%) and Switzerland (8%).

Is 5AM Ventures investing now?

Yes: it is actively investing, with 9 investments in the last 12 months.

Who does 5AM Ventures invest alongside?

Most often Versant Ventures (26 rounds together), OrbiMed (22 rounds together) and ARCH Venture Partners (12 rounds together).

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Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it