United States · Funded startup

Who invested in Spruce Biosciences

2 rounds we have observed, with the 4 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

Pharma

Raised 7 months ago

Funding summaryUpdated 26 Oct 2026

$60Mraised across 2 rounds since 2026, from 2 sources

Latest round
Round, $60MApr 2026
Investors
4
See who backed them

The funding story

Each circle is a round, placed by date and sized by amount. The line above is the running total.

20262027
?Venture$60MRound
First round
Venture
Jan 2026
Biggest round
$60M
Round · Apr 2026
Between rounds
3 months
from the last two

The rounds

  1. Apr 2026
    Round$60M3 returning

    Source recorded

  2. Jan 2026
    VentureAmount undisclosed4 new

    Source recordedSEC filing: $50M sold, first sale Oct 2025

Founders and team

From Spruce Biosciences's own website: 2 on the team.

  • Close ModalChief Executive Officer
  • Michael GreyExecutive Chairman

Who was in which round

The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.

Everyone who backed them

Novo HoldingsVC firm2rounds
Omega FundsVC firm2rounds
Sands Capital VenturesPrivate equity2rounds
5AM VenturesVC firm1round

Missing a round, or an investor who was in one? Tell us.

Also claim to have backed them

These 2 firms list Spruce Biosciences as a portfolio company on their own websites, but no report of a round names them. They are the firms' own claims, kept apart from the rounds above.

Aisling CapitalPrivate equityPer its own site
HealthCapVC firmPer its own site

Quick answers about Spruce Biosciences

Who invested in Spruce Biosciences?

Spruce Biosciences's investors include Novo Holdings, Omega Funds, Sands Capital Ventures and 5AM Ventures.

How much has Spruce Biosciences raised?

Spruce Biosciences has raised $60M across 2 rounds since 2026. One round did not disclose an amount, so the total is a floor.

When did Spruce Biosciences last raise?

Spruce Biosciences's most recent round was an Undisclosed round of $60M in Apr 2026.

What was Spruce Biosciences's biggest round?

Its most recent round, $60M in Apr 2026, is also its largest on record.

Who backed Spruce Biosciences first?

Spruce Biosciences's first round on record, in Jan 2026, was backed by Novo Holdings, 5AM Ventures and Omega Funds and 1 others.

What stage is Spruce Biosciences at?

Spruce Biosciences's latest named round is an Undisclosed round, in Apr 2026.

Where is Spruce Biosciences based?

Spruce Biosciences is based in the United States.

Companies like Spruce Biosciences

In the same sector, and raised in the last eighteen months.

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