What does ARCH Venture Partners invest in?
ARCH Venture Partners invests most often at Series A and Series B (61% of the rounds on record), in sectors such as Information Technology, Life Sciences and Physical Sciences.

United States · Investor
Last cheque observed Oct 2026; 337 cheques on record.
Deploying nowNew fund $2.8B, Aug 2026VC firm
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41 cheques in the last 12 months
Mostly Series A and Series B: 61% of its rounds
Sole investor in 17 rounds, median $18M
19 exits from the portfolio
ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciencesFrom their own website
Every round we can evidence, newest first337 appearances
31 rounds
34 rounds
An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.
Named by the firm itself, on a filing, its Form ADV or its company registration9 named
We also hold 56 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.
From the firm's own filings with the SEC, which it must file accurately by law
Who backs their funds
The institutions that put money into its funds, which the firm then invests in companies.Source: the pension's own report, latest Jun 2025.
| Fund | Vintage | Committed |
|---|---|---|
| ARCH Venture Fund VI | 2004 | $30M |
From their own portfolio page (on their website)
908 DevicesAccompany HealthAgios PharmaceuticalsAkamis BioAledadeAltos LabsArbor BiotechnologiesArraybiopharmaArsenal BiosciencesAspen NeuroscienceBE BiopharmaBasking BiosciencesBluebirdbioBoundlessbioBrii BiosciencesCStone PharmaceuticalsCarricktherapeuticsCytrellis BiosystemsDenali TherapeuticsEncoded TherapeuticsErascaFaraday PharmaceuticalsGate BioscienceGenerate BiomedicinesGossamerbioHiberCellHomologymedicinesHuamedicineJW TherapeuticsJaguar Gene TherapyKardiganKura OncologyLifordi ImmunotherapeuticsLightcast DiscoveryMagnet BiomedicineMatter NeuroscienceMoonwalk BiosciencesONIOmniome (Acquired)OneBioMedParabilis MedicinesPheast TherapeuticsProtillion BiosciencesQihan BiotechQuantum CircuitsRIPPL CareReceptosRecuro HealthScholarrockSingleron BiotechnologiesSlingshot BiosciencesSunBird BioSynchronTreeline BiosciencesTwist BioscienceUltivueUnitybiotechnologyVir BiotechnologyVividionVizgenand 39 more
Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.
Companies it backed that were later bought or listed19 in all
An exit counts when it came after the firm's first round in the company. From historical deal records.
The investors most often in the same rounds as ARCH Venture Partners. A count of rooms they were both in, not a relationship either has claimed.
The latest companies ARCH Venture Partners put money into.
Episodes that name ARCH Venture Partners in their description, not their title.

Diligence Questions: As Simple As They Are Complex | Youngrok Kim | Superclusters | S2E2

Youngrok Kim on Japanese Corporate Venture Capital, Korea Army in Iraq & The Owner of Indeed & Glassdoor - E58
MentionsARCH Venture Partners
ARCH Venture Partners invests most often at Series A and Series B (61% of the rounds on record), in sectors such as Information Technology, Life Sciences and Physical Sciences.
337 investments on record, 41 of them in the last 12 months, and it led 12. The most recent was in Oct 2026.
Its most recent investments on record: Soufflé Therapeutics (Series B, Oct 2026), Oratomic (Series B, Oct 2026) and Encoded Therapeutics (Series F, Sept 2026).
The median round it joins is $74M. It says it writes cheques of $50K to $150M.
Sometimes: it led 12 of its 337 investments on record (4%).
Most of the companies it backs are in the United States (92%) and the United Kingdom (5%).
Yes: it is actively investing, with 41 investments in the last 12 months.
Most often Polaris Partners (34 rounds together), Venrock (27 rounds together) and Fidelity (24 rounds together).
Find the investors who back rounds like yours, and keep every conversation on one fundraising board.
Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it