United States · Investor

Omega Funds

Last cheque observed Sep 2026; 104 cheques on record.

Deploying nowNew fund $580M, Apr 2025VC firm

BuyoutGrowthPre-seedOncologyImmunologyRare_diseases

Deploying now
89%of best year17cheques in 12 months, 104 on record
Since the last cheque38days00hrs00min00sec
Median round$88MRounds led8 of 104Sole investor5 roundsExits1 from the portfolioMostly inUnited States, 83%
Pitch Omega Funds

Omega Funds highlights

  1. 01

    17 cheques in the last 12 months

  2. 02

    Mostly Series A and Series B: 63% of its rounds

  3. 03

    Sole investor in 5 rounds, median $2.6M

  4. 04

    1 exits from the portfolio

What they do

We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas, including oncology, immunology, rare diseases, precision medicine and others.From their own website
Type
VC firm
Cheque size
Not stated
Stages
BuyoutGrowthPre-seedSeedSeries ASeries B
Sectors
OncologyImmunologyRare_diseases
Based in
Boston, United States
Cold pitches
Not accepted

The record

Every round we can evidence, newest first104 appearances

  1. 2026

    14 rounds

  2. Sept
    Anaconda BiomedSeries C · ES · Asabys$56MLed
  3. Sept
    Beta BionicsUS$173MWith 3 others
  4. Aug
    Vaderis TherapeuticsSeries B · CH · Firms' own news pages$152MWith 8 others
  5. May
    Editas MedicineUS$125MWith 3 others
  6. May
    Sana BiotechnologyUS$69MWith 4 others
  7. Apr
    Trevi TherapeuticsUS$173MWith 3 others
  8. Apr
    Spruce BiosciencesUS$60MWith 2 others
  9. Feb
  10. Feb
    Beam TherapeuticsDebt · US$100MWith 5 others
  11. Jan
    Alveus TherapeuticsSeries A · US · Avego Management$160MLed
  12. Jan
    Spruce BiosciencesVenture · USUndisclosedWith 3 others
  13. Jan
    AlumisUS$345MWith 6 others
  14. Jan
    Caldera TherapeuticsSeries A · US$38MWith 4 others
  15. Jan
    Spiro MedicalSeries A · US$67MWith 4 others
  16. 2025

    14 rounds

  17. Dec
  18. Dec
    FoRx TherapeuticsSeries A · CH$50MWith 1 other
  19. Dec
    Protego BiopharmaSeries B · US · Firms' own news pages$130MWith 9 others
  20. Sept
    NRG TherapeuticsSeries B · GB · Firms' own news pages$68MWith 6 others
  21. Jul
    ARTBIOSeries B · US$132MWith 1 other
  22. Jun
    Trevi TherapeuticsUS$115MWith 3 others
  23. May
    Ousia PharmaVenture · DKUndisclosedWith 1 other
  24. May
    Senti BiosciencesGrant · US$1.0MWith 4 others
  25. May
    Antares TherapeuticsSeries A · US$177MWith 2 others
  26. Apr
    HydrocisionVenture · US$2.5MSole investor
  27. Mar
    Nuvation BioDebt · US$150MWith 3 others
  28. Mar
    Callio TherapeuticsSeries A · US$187MWith 3 others
  29. Jan
    Windward BioSeries A · CH$200MWith 4 others
  30. Jan
    Alleviant MedicalVenture · US · Vensana Capital$90MWith 2 others
  31. 2024

    9 rounds

  32. Nov
    Beta BionicsSeries E · US$60MWith 4 others
  33. Nov
    Replimune GroupUS$140MWith 5 others
  34. Aug
    XII MedicalSeries B · US$45MWith 1 other
  35. Jul
    Scorpion TherapeuticsSeries C · US$150MWith 4 others
  36. Jul
    Vanqua BioVenture · US$45MWith 3 others
  37. Jul
    CatalYmSeries D · DE$150MWith 3 others
  38. Jun
    Marea TherapeuticsSeries B · US$190MWith 3 others
  39. May
    BbotVenture · US$200MWith 4 others
  40. Apr
    Endeavor BioMedicinesSeries C · US$133MWith 2 others
  41. 2023

    8 rounds

  42. Nov
    Alpine Immune SciencesUS$150MWith 4 others
  43. Nov
    EyebiotechSeries A · US$65MWith 4 others
  44. Jul
    Gossamer BioUS$212MWith 5 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

The team

Named by the firm itself, on a filing, its Form ADV or its company registration9 named

ARAlexandra Rankel PearsallChief Financial OfficeriForm ADV
APAnne-Mari PasterDirectoriFiling they signed
CPClaudio Pier Antonio NessiManager & MemberiForm ADV
FLFrancesco Luigi DraettaManager & MemberiForm ADV
KBKevin BrennanA Director of the general partner of the General PartneriFiling they signed
MEMark Emerson RussellChief Compliance OfficeriForm ADV
O(Otello (nmn) StampacchiaA Director of the general partner of the General PartneriFiling they signed
RLRichard LimDirectoriFiling they signed
SASharon AlvarezA Director of the general partner of the General PartneriFiling they signed

We also hold 16 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

What the register says

From the firm's own filings with the SEC, which it must file accurately by law

$1.7Bassets it managesOct 2026
Registeredinvestment adviserfull reporting to the SEC
Legal name
Omega Fund Management, LLC
SEC number
CRD 157753

Funds on its Form ADV

8 private funds, $694M in gross assets · filed Mar 2024

  1. Omega Fund VII, L.P.Private equity87 investors$324M
  2. Omega Fund VI, L.P.Private equity45 investors$268M
  3. Omega Fund V, L.P.Private equity34 investors$68M
  4. Omega Fund IV, L.P.Private equity37 investors$29M
  5. NET Assets of Omega Fund III, L.P.Private equity15 investors$3.1M
  6. Omega Fund II, L.P.Private equity6 investors$1.7M
  7. Life Sciences Holdings SPV I Fund, L.P.Private equity1 investor$190K
  8. Omega Fund VIII, L.P.Private equity42 investors-

What they claim to have backed

From their own portfolio page (on their website)

0 of 4 we have independently watched raise

Omega Fund VS3Show + TellSscfundservices

Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.

Exits from the portfolio

Companies it backed that were later bought or listed1 in all

Santaris PharmaBought by Roche$450MAug 2014

An exit counts when it came after the firm's first round in the company. From historical deal records.

Who they invest alongside

The investors most often in the same rounds as Omega Funds. A count of rooms they were both in, not a relationship either has claimed.

Recently backed

The latest companies Omega Funds put money into.

Mentioned on podcasts

Episodes that name Omega Funds in their description, not their title.

Quick answers about Omega Funds

What does Omega Funds invest in?

Omega Funds invests most often at Series A and Series B (63% of the rounds on record), in sectors such as Oncology, Immunology and Rare_diseases.

How active is Omega Funds?

104 investments on record, 17 of them in the last 12 months, and it led 8. The most recent was in Sept 2026.

What has Omega Funds invested in recently?

Its most recent investments on record: Anaconda Biomed (Series C, Sept 2026), Beta Bionics (Undisclosed round, Sept 2026) and Vaderis Therapeutics (Series B, Aug 2026).

How big are Omega Funds's cheques?

The median round it joins is $88M.

Does Omega Funds lead rounds?

Sometimes: it led 8 of its 104 investments on record (8%).

Where does Omega Funds invest?

Most of the companies it backs are in the United States (83%) and Switzerland (8%).

Is Omega Funds investing now?

Yes: it is actively investing, with 17 investments in the last 12 months.

Who does Omega Funds invest alongside?

Most often Atlas Venture (10 rounds together), Perceptive Advisors (10 rounds together) and Cormorant Asset Management (9 rounds together).

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Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it