What does Lightstone Ventures invest in?
Lightstone Ventures invests most often at Series B and Series A (76% of the rounds on record), in sectors such as Lifescience, Psychedelics and Ivd.

United States · Investor
Last cheque observed Aug 2025. Silence since then is not evidence of inactivity: our sources miss unannounced rounds.
QuietNew fund $375M, Sept 2021VC firm
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22 rounds on record
Mostly Series B and Series A: 76% of its rounds
Led 1 rounds
Our experienced life science investors seek out visionary founders to translate novel scientific breakthroughs into clinically and commercially meaningful therapies.From their own website
Every round we can evidence, newest first22 appearances
4 rounds
1 round
4 rounds
4 rounds
2 rounds
1 round
2 rounds
3 rounds
1 round
An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.
Named by the firm itself, on a filing, its Form ADV or its company registration9 named
We also hold 18 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.
From the firm's own filings with the SEC, which it must file accurately by law
From their own portfolio page (on their website)
AcceleronpharmaAlxoncologyCalahealthCarricktherapeuticsCerevanceClaretmedicalContegomedicalCyteirEndogastricsolutionsFire1foundryFlex-pharmaGynesonicsHydrabiosciencesMersanaMoximedPlexxikonPortolaProverummedicalRelievantSetpointmedicalShoulderinnovationsTallactherapeuticsThefoundryVerastemVolta-medical65lab.sgAlchemabBioVenture VoiCes EpisodeBonitobioCardiacboosterCoolsculptingFiveprimeMicroventionPowervisionlensProVerum ProVee SystemProVerum’s CFO HirePsitheraRapharmaReprievecardioTagworkspharmaTrotanaVigilneuro
Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.
The investors most often in the same rounds as Lightstone Ventures. A count of rooms they were both in, not a relationship either has claimed.
The latest companies Lightstone Ventures put money into.
Lightstone Ventures invests most often at Series B and Series A (76% of the rounds on record), in sectors such as Lifescience, Psychedelics and Ivd.
22 investments on record, 0 of them in the last 12 months, and it led 1. The most recent was in Aug 2025.
Its most recent investments on record: ProVerum Medical (Series B, Aug 2025), Apreo Health (Series B, Aug 2025) and Allay Therapeutics (Series D, Jun 2025).
The median round it joins is $61M. It says it writes cheques of $100K to $5.0M.
Sometimes: it led 1 of its 22 investments on record (5%).
Most of the companies it backs are in the United States (86%) and Ireland (14%).
No investments in the last 12 months; the latest was in Aug 2025.
Most often New Enterprise Associates (6 rounds together), Atlas Venture (3 rounds together) and OrbiMed (3 rounds together).
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Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it