United States · Investor

Flagship Pioneering, LLC

Last cheque observed Dec 2013. Silence since then is not evidence of inactivity: our sources miss unannounced rounds.

QuietVC firm

Series ASeries BSeries C

Cheques on record
0%of best year0cheques in 12 months, 95 on record
Since the last cheque4712days00hrs00min00sec
Median round$14MRounds led0 of 95Sole investor6 roundsExits15 from the portfolioMostly inUnited States, 100%
Pitch Flagship Pioneering, LLC

Flagship Pioneering, LLC highlights

  1. 01

    95 rounds on record

  2. 02

    Mostly Series A and Series B: 46% of its rounds

  3. 03

    Sole investor in 6 rounds, median $9.7M

  4. 04

    15 exits from the portfolio

What they do

SEC Form ADV: exempt reporting adviserFrom their own website
Type
VC firm (from a list, unverified)
Cheque size
Not stated
Based in
Cambridge, MA, United States
Cold pitches
Not stated

The record

Every round we can evidence, newest first95 appearances

  1. 2013

    8 rounds

  2. Dec
    VisterraSeries A · US · finsmes.com$8.1MWith 4 others
  3. Nov
    Editas MedicineSeries A · US · finsmes.com$43MWith 3 others
  4. Nov
    Seres HealthSeries A · US · finsmes.com$11MWith 1 other
  5. Oct
    Pronutria Biosciences, Inc.Series A · US · pehub.com$11MSole investor
  6. Apr
    Syros PharmaceuticalsSeries A · US · syros.com$30MWith 1 other
  7. Mar
    T2 BiosystemsSeries E · US · pevc.dowjones.com$40MWith 9 others
  8. Mar
    TARIS BiomedicalGrowth · US · sec.gov$14MWith 3 others
  9. Mar
    AvedroSeries D · US · boston.com$43MWith 7 others
  10. 2012

    10 rounds

  11. Dec
    Blend TherapeuticsSeries B · US · finance.yahoo.com$16MWith 2 others
  12. Dec
    Moderna TherapeuticsVenture · US · masshightech.com$40MSole investor
  13. Nov
    QuanterixSeries C · US · masshightech.com$19MWith 3 others
  14. Nov
    VisterraSeries A · US · sec.gov$26MWith 4 others
  15. Sept
    WikiCell DesignsSeries A · US · finsmes.com$10MWith 2 others
  16. Jun
    Seventh Sense BiosystemsSeries A · US · finsmes.com$10MWith 1 other
  17. May
    Eleven BiotherapeuticsSeries A · US · masshightech.com$20MWith 3 others
  18. Mar
    ReceptosVenture · US$30MWith 5 others
  19. Feb
    PolatisVenture · US · polatis.com$2.7MWith 5 others
  20. Jan
    Blend TherapeuticsSeries A · US · biocentury.com$2.8MWith 1 other
  21. 2011

    6 rounds

  22. Nov
    Agios PharmaceuticalsSeries C · US · finsmes.com$78MWith 3 others
  23. Aug
    T2 BiosystemsSeries D · US · masshightech.com$23MWith 9 others
  24. Jun
    KovioVenture · US · finsmes.com$15MWith 6 others
  25. Jun
    ExactCostVenture · US · fis.dowjones.com$8.5MSole investor
  26. May
    Seventh Sense BiosystemsSeries A · US · 7sbio.com$4.5MWith 2 others
  27. Apr
    TARIS BiomedicalSeries B · US · eon.businesswire.com$18MWith 3 others
  28. 2010

    12 rounds

  29. Dec
    LS9Series D · US$30MWith 5 others
  30. Oct
    Accuri CytometersSeries E · US · onbiovc.com$6.0MWith 5 others
  31. Aug
    VisterraDebt · US · sec.gov$6.0MWith 2 others
  32. Jun
    BIND TherapeuticsSeries C · US · fiercebiotech.com$12MWith 4 others
  33. Jun
    Acceleron PharmaVenture · US · masshightech.com$8.4MWith 4 others
  34. Jun
    Everyday SolutionsVenture · US · sec.gov$2.8MWith 2 others
  35. Jun
    Tetraphase PharmaceuticalsSeries C · US · fiercebiotech.com$45MWith 7 others
  36. May
    T2 BiosystemsSeries C · US · onbiovc.com$15MWith 8 others
  37. Apr
    Joule UnlimitedSeries B · US · jouleunlimited.com$30MSole investor
  38. Apr
    Selecta BiosciencesSeries C · US · freshnews.com$15MWith 4 others
  39. Mar
    TransMedicsSeries E · US · onbiovc.com$36MWith 10 others
  40. Mar
    Eleven BiotherapeuticsSeries A · US · onbiovc.com$35MWith 1 other
  41. 2009

    14 rounds

  42. Nov
    ReceptosSeries A · US · fiercebiotech.com$25MWith 3 others
  43. Oct
    LS9Series C · US · onbiovc.com$25MWith 4 others
  44. Sept
    Alvine PharmaceuticalsSeries A · US · deals.venturebeat.com$22MWith 5 others
  45. Aug
    Pervasis TherapeuticsSeries C · US · news.prnewswire.com$17MWith 2 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

The team

Named by the firm itself, on a filing, its Form ADV or its company registration2 named

CRCharles Robert CarelliCFOiForm ADV
NBNoubar B AfeyanCEO & PresidentiForm ADV

We also hold 2 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

What the register says

From the firm's own filings with the SEC, which it must file accurately by law

$13Bgross assets of its fundsOct 2026
Exemptreporting adviserventure or small private funds
Legal name
Flagship Pioneering, LLC
SEC number
CRD 161864

Exits from the portfolio

Companies it backed that were later bought or listed15 in all

ReceptosBought by Celgene$7.3BJul 2015
LS9Bought by Renewable Energy Group$62MJan 2014
KovioBought by Thin Film Electronics ASA$3.7MJan 2014
Agios PharmaceuticalsListed$86MJun 2013
Everyday SolutionsBought by Synovia, Inc.UndisclosedSept 2012
TripAdvisorListedUndisclosedDec 2011
Accuri CytometersBought by (Becton, Dickinson and Company)UndisclosedMar 2011
AdnexusBought by Bristol-Myers Squibb$415MAug 2010
Interactive SupercomputingBought by MicrosoftUndisclosedSept 2009
Calpurnia CorporationBought by Tyco InternationalUndisclosedJul 2008
ZingkuBought by GoogleUndisclosedSept 2007
AdnexusBought by Bristol-Myers Squibb$415MSept 2007
TripAdvisorBought by ExpediaUndisclosedAug 2005
TripAdvisorBought by IAC$210MMar 2004

An exit counts when it came after the firm's first round in the company. From historical deal records.

Who they invest alongside

The investors most often in the same rounds as Flagship Pioneering, LLC. A count of rooms they were both in, not a relationship either has claimed.

Quick answers about Flagship Pioneering, LLC

What does Flagship Pioneering, LLC invest in?

Flagship Pioneering, LLC invests most often at Series A and Series B (46% of the rounds on record).

How active is Flagship Pioneering, LLC?

95 investments on record, 0 of them in the last 12 months. The most recent was in Dec 2013.

How big are Flagship Pioneering, LLC's cheques?

The median round it joins is $14M.

Does Flagship Pioneering, LLC lead rounds?

Rarely, if at all: none of its 95 investments on record names it as the lead.

Where does Flagship Pioneering, LLC invest?

Most of the companies it backs are in the United States (100%).

Is Flagship Pioneering, LLC investing now?

No investments in the last 12 months; the latest was in Dec 2013.

Who does Flagship Pioneering, LLC invest alongside?

Most often Polaris Partners (26 rounds together), Kleiner Perkins Caufield & Byers (8 rounds together) and ARCH Venture Partners (7 rounds together).

What kind of investor is Flagship Pioneering, LLC?

Flagship Pioneering, LLC is a VC firm based in Cambridge, MA, United States.

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Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it