Sector portfolio · Private equity · United States

OrbiMed's Biotech portfolio

OrbiMed has backed 176 Biotech startups in rounds we track, $28B between them, shown by the stage each has reached. The best-funded is Apogee Therapeutics.

176startups backed
6stages
$28Braised between them
Series C and laterbiggest stage

OrbiMed's whole portfolioOrbiMed's profile

Series C and later

46

+22 more

Series B

45

+21 more

Stage not reported

44

+20 more

Series A

37

+13 more

Pre-seed and seed

2

Growth

2

Segment by segment

Series C and later

46 startups · $6.9B raised

  1. Guardant HealthGuardant Health is a leading precision medicine company focused on transforming patient care and conquering cancer with data.United States$800M
  2. IMInsilico MedicineHong Kong SAR China$392M
  3. GalectoGalecto is a clinical stage biotechnology company focused on the development of novel treatments for fibrosis and cancer.Denmark$365M
  4. Star TherapeuticsStar Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018.United States$325M
  5. Terremoto BiosciencesTerremoto Biosciences is a clinical-stage biotechnology company founded in 2021, focused on covalent drug discovery and development.United States$283M
  6. InventisBioInventisBio is a clinical-stage biopharmaceutical company based in Shanghai, China, with operations in New Jersey, USA.China$236M
  7. AlectorAlector is a biopharmaceutical company that develops therapies for the treatment of neurodegeneration diseases.United States$215M
  8. ADCendoAdcendo ApS is a clinical-stage biotechnology company based in Frederiksberg, Copenhagen, Denmark, with operational offices in BosDenmark$210M

Series B

45 startups · $6.6B raised

  1. Terns PharmaceuticalsTerns Pharmaceuticals is a biopharmaceutical company that focuses on discovering therapies that will improve the global disease burden.United States$730M
  2. Intellia TherapeuticsIntellia Therapeutics is a genome editing company that develops curative gene-editing treatments.United States$485M
  3. SpringWorks TherapeuticsSpringWorks Therapeutics is a biopharmaceutical company that develops medicines for patients with severe rare diseases and cancer.United States$400M
  4. Passage BioPassage Bio is a fully integrated gene therapy company developing therapies for the treatment of monogenic central nervous system diseases.United States$380M
  5. Acutus MedicalAcutus Medical develops medical technologies to treat complex cardiac arrhythmia.United States$268M
  6. Aeglea BioTherapeuticsAeglea BioTherapeutics is a clinical-stage biotechnology company that develops enzyme therapies for rare metabolic diseases.United States$266M
  7. Repare TherapeuticsRepare Therapeutics is a developer of oncology drugs designed to target specific vulnerabilities of tumor cells.Canada$252M
  8. Upstream BioUpstream Bio focuses on developing an antibody therapy for the treatment of severe asthma.United States$200M

Stage not reported

44 startups · $8.5B raised

  1. Apogee TherapeuticsApogee Therapeutics is a biotechnology company that offers therapies for immunological and inflammatory disorders.United States$1.3B
  2. Tyra BiosciencesTyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.United States$600M
  3. Avalo TherapeuticsAvalo Therapeutics is a clinical-stage biopharmaceutical company.United States$501M
  4. TPTurning Point TherapeuticsTurning Point Therapeutics is a pharmaceutical company that discovers and develops precision medicines for cancer and other diseases.-$460M
  5. Enliven TherapeuticsEnliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives.United States$460M
  6. Puma BiotechnologyPuma Biotechnology acquires and develops innovative products for the treatment of various forms of cancer.United States$427M
  7. Century TherapeuticsCentury Therapeutics is a biotechnology company that develops cell therapies for hematological and solid tumor malignancies.United States$385M
  8. Dren BioDren Bio focuses on protein engineering technologies for depletion of cells, protein aggregates, and other disease-causing agents.United States$375M

Series A

37 startups · $5.4B raised

  1. ErascaErasca is a developer of oncology drugs intended to provide precision oncology options.United States$739M
  2. Nuvation BioNuvation Bio is a global biopharmaceutical company focusing on unmet needs in oncology.United States$675M
  3. Verdiva BioVerdiva Bio is a clinical-stage biopharmaceutical company based in Guildford, United Kingdom, founded in 2024.United Kingdom$601M
  4. 89Bio89bio is a biopharmaceutical company that develops clinical-stage therapies for liver and cardiometabolic diseases.United States$348M
  5. Rhythm PharmaceuticalsRhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeuticsUnited States$311M
  6. Treeline BiosciencesTreeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.United States$200M
  7. AirNexis TherapeuticsAirNexis Therapeutics develops clinical-stage therapies for chronic obstructive pulmonary disease and other pulmonary conditions.United States$200M
  8. Alpine Immune SciencesAlpine Immune Sciences is an immunotherapy company focused on developing treatments for autoimmune and inflammatory diseases.United States$199M

Pre-seed and seed

2 startups · $97M raised

  1. Renasant BioRenasant Bio is a biopharmaceutical company based in Berkeley, California, focused on developing oral small molecule therapies forUnited States$55M
  2. RRhythmUnited States$42M

Growth

2 startups · $496M raised

  1. DKDingdang KuaiyaoDingdang Kuaiyao is an online-to-offline drug purchasing and delivery platform.China$309M
  2. GC AestheticsHá 25 anos a Eurosilicone vem produzindo próteses de silicone, conforme os mais rigorosos padrões de qualidade e segurança e auxilIreland$187M

How this map is made. Every startup here works in Biotech and has raised money in a round we track that names OrbiMed as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

More portfolio maps

All portfolios
Sector portfolioOrbiMed's Pharma portfolio26 startups · $3.7BSector portfolioOrbiMed's Healthtech portfolio12 startups · $1.4BPortfolio mapOrbiMed portfolio map221 startups · $34BCo-investorsWho invests with OrbiMed159 co-investorsSector portfolioRA Capital Management's Biotech portfolio197 startups · $38BSector portfolioPioneer Fund's AI portfolio171 startups · $2.8B

Raising from investors like OrbiMed?

Find the investors who back startups like yours, with their cheques, rounds and partners, in the app with filters, lists and exports.

Find investorsMarket maps