United States · Funded startup

Who invested in Rhythm Pharmaceuticals

10 rounds we have observed, with the 9 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

Biotech

Funding summaryUpdated 26 Oct 2026

$311Mraised across 10 rounds since 2010, from 10 sources

$21MSeries A$19MSeries A$9.5MVenture$25MSeries B$8.0MSeries B$11MSeries B$1.4MGrant$40MSeries A$1.0MGrant$175MRound
Latest round
Round, $175MJul 2025
Step-upi
175×
Investors
9
See who backed them

The funding story

Each circle is a round, placed by date and sized by amount. The line above is the running total.

20102012201420162018202020222024
$21MSeries A$19MSeries A$9.5MVenture$25MSeries B$40MSeries A$1.0MGrant$175MRound
First round
Series A, $21M
Mar 2010
Biggest round
$175M
Round · Jul 2025
Usual gap between rounds
8 months
the median of 8

The rounds

  1. Jul 2025
    Round$175M2 returning

    Source recorded

  2. Sept 2015
    Grant$1.0M

    No investor was named in the report.

    From a historical funding recordSEC filing: $40M sold, first sale Aug 2015

  3. Aug 2015
    Series A$40M3 new5 returning

    From a historical funding recordSEC filing: $40M sold, first sale Aug 2015

  4. Sept 2013
    Grant$1.4M1 new

    Reported by bizjournals.com

  5. Jul 2013
    Series B$11M

    No investor was named in the report.

    Reported by biospace.com

  6. Nov 2012
    Series B$8.0M1 new4 returning

    Reported by pehub.comSEC filing: $23M sold, first sale May 2012

  7. Jun 2012
    Series B$25M2 new2 returning

    Reported by rhythmtx.comSEC filing: $9.5M sold, first sale May 2012

  8. Jun 2012
    Venture$9.5M

    No investor was named in the report.

    Reported by masshightech.comSEC filing: $9.5M sold, first sale May 2012

  9. Sept 2010
    Series A$19M

    No investor was named in the report.

    Reported by genengnews.comSEC filing: $18M sold, first sale Mar 2010

  10. Mar 2010
    Series A$21M2 new

    Reported by fiercebiotech.comSEC filing: $10M sold, first sale Mar 2010

Founders and team

From Rhythm Pharmaceuticals's own website and the SEC filings it signed: 8 on the team.

  • Keith GottesdienerMr. Gottesdiener is the Chief Executive Officer of the Issuer.i
  • Jennifer LeeExecutive Vice President, Head of North America
  • Jim FlahertySenior Vice President and General Counsel
  • Yann MazabraudExecutive Vice President, Head of International
  • Bart T. HendersonMr. Henderson is the President and Treasurer of the Issuer.i
  • Alicia FiscusChief Regulatory Officer
  • Hunter SmithChief Financial Officer
  • Joe ShulmanChief Technical Officer

On the board, as filediChristophe JeanDavid J. McGirrDavid P. MeekerEdward T. MathersJonathan T. SilversteinNeil ExterTodd T. Foley

Who was in which round

The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.

Venture2012Series B2012Series B2012Series B2013Grant2013Series A2015Grant2015Round2025New Enterprise AssociatesMPM CapitalThird Rock VenturesIpsenOrbiMedPfizerWellington ManagementDeerfieldMichael J. Fox Foundation

Everyone who backed them

MPM CapitalPrivate equity4rounds
Third Rock VenturesVC firm3rounds
IpsenCorporate VC3rounds
OrbiMedPrivate equity2rounds
PfizerCorporate VC2rounds
DeerfieldVC firm1round
Michael J. Fox FoundationAccelerator1round

Missing a round, or an investor who was in one? Tell us.

Quick answers about Rhythm Pharmaceuticals

Who invested in Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals's investors include New Enterprise Associates, MPM Capital, Third Rock Ventures, Ipsen and OrbiMed, and 4 more on record.

How much has Rhythm Pharmaceuticals raised?

Rhythm Pharmaceuticals has raised $311M across 10 rounds since 2010.

When did Rhythm Pharmaceuticals last raise?

Rhythm Pharmaceuticals's most recent round was an Undisclosed round of $175M in Jul 2025.

What was Rhythm Pharmaceuticals's biggest round?

Its most recent round, $175M in Jul 2025, is also its largest on record.

Who backed Rhythm Pharmaceuticals first?

Rhythm Pharmaceuticals's first round on record, in Mar 2010, was backed by New Enterprise Associates and MPM Capital.

What stage is Rhythm Pharmaceuticals at?

Rhythm Pharmaceuticals's latest named round is an Undisclosed round, in Jul 2025.

Where is Rhythm Pharmaceuticals based?

Rhythm Pharmaceuticals is based in the United States.

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