United States · Series B startup

Who invested in Upstream Bio

One round we have observed, with the 7 investors named in it. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

Biotech

Funding summaryUpdated 26 Oct 2026

$200Mraised across 1 round since 2023, from 1 source

Latest round
Series B, $200MJun 2023
Investors
7
See who backed them

The rounds

  1. Jun 2023

Founders and team

From Upstream Bio's own website: 6 on the team.

  • Daniella BeckmanChief Executive Officer
  • Amy IannelliVice President, Finance
  • Ken AdamsSenior Vice President, Clinical Operations & Medical Writing
  • Lisa FieringSenior Vice President, People & Culture
  • Allison AmbroseGeneral Counsel
  • Ron RenaudChair, Board of Directors

Everyone who backed them

OrbiMedPrivate equity1round
TCGPrivate equity1round
Omega FundsVC firm1round
Samsara BioCapitalVC firm1round
TCG CrossoverVC firm1round
Bain Capital Life SciencesPrivate equity1round

Missing a round, or an investor who was in one? Tell us.

Also claim to have backed them

This firm lists Upstream Bio as a portfolio company on their own website, but no report of a round names it. They are the firms' own claims, kept apart from the rounds above.

Decheng CapitalVC firmPer its own site

Quick answers about Upstream Bio

Who invested in Upstream Bio?

Upstream Bio's investors include OrbiMed, Wellington Management, TCG, Omega Funds and Samsara BioCapital, and 2 more on record.

How much has Upstream Bio raised?

Upstream Bio has raised $200M across 1 round since 2023.

When did Upstream Bio last raise?

Upstream Bio's most recent round was a Series B of $200M in Jun 2023.

What was Upstream Bio's biggest round?

Its most recent round, $200M in Jun 2023, is also its largest on record.

Who backed Upstream Bio first?

Upstream Bio's first round on record, in Jun 2023, was backed by OrbiMed, Wellington Management and TCG and 4 others.

What stage is Upstream Bio at?

Upstream Bio's latest named round is a Series B, in Jun 2023.

Where is Upstream Bio based?

Upstream Bio is based in the United States.

Companies like Upstream Bio

In the same sector, and raised in the last eighteen months.

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