Who invested in Upstream Bio?
Upstream Bio's investors include OrbiMed, Wellington Management, TCG, Omega Funds and Samsara BioCapital, and 2 more on record.

United States · Series B startup
Funding summaryUpdated 26 Oct 2026
$200Mraised across 1 round since 2023, from 1 source
Source recorded
From Upstream Bio's own website: 6 on the team.
Upstream Bio's investors include OrbiMed, Wellington Management, TCG, Omega Funds and Samsara BioCapital, and 2 more on record.
Upstream Bio has raised $200M across 1 round since 2023.
Upstream Bio's most recent round was a Series B of $200M in Jun 2023.
Its most recent round, $200M in Jun 2023, is also its largest on record.
Upstream Bio's first round on record, in Jun 2023, was backed by OrbiMed, Wellington Management and TCG and 4 others.
Upstream Bio's latest named round is a Series B, in Jun 2023.
Upstream Bio is based in the United States.
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