Portfolio map · Government fund · United States

National Science Foundation portfolio map

988 startups National Science Foundation has backed in rounds we track, since 2010, grouped by their main sector. Together they have raised $10B. The biggest sector is Biotech, with 251 companies.

988startups backed
12sectors
$10Braised between them
Biotechbiggest sector

National Science Foundation's investor profile

Biotech

251

+227 more

Healthtech

149

+125 more

AI

118

+94 more

Chemicals & Materials

75

+51 more

Agtech

57

+33 more

Big Data & Analytics

56

+32 more

Hardware & Electronics

54

+30 more

Energy

53

+29 more

Cleantech

46

+22 more

Manufacturing

46

+22 more

Advanced Manufacturing

43

+19 more

Edtech

40

+16 more

Segment by segment

Biotech

251 startups · $2.0B raised

  1. Spero TherapeuticsSpero Therapeutics develops therapeutics for treatment of gram-negative infections.United States$199M
  2. Caribou BiosciencesCaribou Biosciences is a biotechnology company that develops CRISPR technologies and allogenic cell therapies for oncology.United States$139M
  3. Lucira HealthLucira Health is a biotechnology company that offers disposable test kits to detect RNA and DNA of infectious diseases.United States$95M
  4. GRO BiosciencesGRO Biosciences, also known as GRObio, is a biotechnology company based in Cambridge, Massachusetts, founded in 2016.United States$87M
  5. ProLynxProlynx is a clinical-stage biotechnology company based in the San Francisco Bay Area, founded in 2009.United States$70M
  6. ArzedaWe harness the power of Intelligent Protein Design TechnologyTM to create enzyme products solving industry's toughest challengesUnited States$65M
  7. BreezeBioBreezeBio, Inc., based in South San Francisco, California, is a biotechnology company founded in 2016 by Dr.United States$60M
  8. CoreMapCoreMap is a medical device company founded in 2016, focused on advanced diagnostic technology for electrophysiologists.United States$57M

Healthtech

149 startups · $516M raised

  1. Osso VROsso VR is a virtual reality platform founded in 2016 that enhances surgical training and assessment for healthcare professionals United States$68M
  2. ZZenflowUnited States$56M
  3. NeocisNeocis is a medical technology company based in Miami, Florida, that specializes in robotic-assisted solutions for the dental induUnited States$52M
  4. Health FidelityHealth Fidelity offers risk adjustment and quality solutions for healthcare organizations participating in risk-based payment programs.United States$39M
  5. Huxley MedicalHuxley Medical is a private company that specializes in medical devices.United States$29M
  6. Moving AnalyticsMoving Analytics is a telehealth service provider that specializes in cardiovascular prevention programs.United States$20M
  7. EyebotEyebot is a Boston-based health-tech company founded in 2021.United States$20M
  8. Avisi TechnologiesAvisi Technologies is a clinical-stage medical device company based in Redwood City, California, founded in 2017.United States$17M

AI

118 startups · $1.9B raised

  1. SamaySamay Health, founded in 2018 by Dr.United States$250M
  2. IAMBICAI-driven, precision-fit footwear.United States$167M
  3. Allen Institute for Artificial IntelligenceAllen Institute for Artificial Intelligence (AI2) is an artificial intelligence research institute and start-up incubator.United States$152M
  4. VVITALCanada$105M
  5. EEdenUnited States$104M
  6. ElucidElucid enables precision medicine for cardiovascular disease by applying A.I to medical image analysis validated against true biology.United States$92M
  7. ModeMODE is driven to help organizations leverage their data to improve operations, safety, & efficiencies through the use of IoT & AIUnited States$70M
  8. AvicenaAvicena is a developer of medical devices and algorithms used to easily assess cardiovascular health.United States$65M

Chemicals & Materials

75 startups · $797M raised

  1. Phoenix TailingsFounded to bring a new level of sustainability and efficiency to the mining industry by enabling new sources of primary metals.United States$530M
  2. Li IndustriesLi Industries is a climate tech company based in Pineville, North Carolina, founded in 2017.United States$55M
  3. UbiQDUbiQD is an advanced materials company that manufactures low-hazard quantum dots (QDs) and nanocomposites.United States$28M
  4. Boston MaterialsBoston Materials is a manufacturer of advanced materials for semiconductors and aerospace platforms.United States$15M
  5. Resource ChemicalReSource is turning CO2 to make high performance plastics that does not accumulate in the environmentUnited States$15M
  6. VenoStentVenoStent is a tissue engineering medical device company developing bioabsorbable polymer wraps for better outcomes in vascular surgery.United States$14M
  7. VartegaVartega is an environmental services company founded in 2014, based in Denver, Colorado.United States$13M
  8. Phase Two ChemicalsPhase Two Chemicals specializes in clean chemistry and industrial electrochemistry, focusing on on-site, on-demand hydrogen peroxiUnited States$12M

Agtech

57 startups · $636M raised

  1. PProviviUnited States$124M
  2. CalystaCalysta is a biotechnology company based in California, specializing in cellular agriculture.United States$109M
  3. TARGANTARGAN is a bio-systems company focused on improving animal health and productivity in the poultry, livestock, and aquaculture industries.United States$65M
  4. NitricityNitricity is a climate-tech agri startup founded in 2018 by Stanford University graduates.United States$64M
  5. ArableThe Arable mission is to reduce the costs of biomedical technology, products, services, R&D while enabling a new era of personalizUnited States$40M
  6. AgroSpheresAgroSpheres develops novel technologies that aim to set a new standard for bio-based delivery of active ingredients.United States$38M
  7. Blue River TechnologyWe’re Blue River, a team of innovators driven to radically change agriculture by creating intelligent machinery.United States$30M
  8. Sound AgricultureSound Agriculture is an AgriTech company founded in 2013, based in Emeryville, California, with additional operations in Raleigh, United States$25M

Big Data & Analytics

56 startups · $534M raised

  1. ScaleFluxScaleFlux is a semiconductor and enterprise storage innovator founded in 2014, headquartered in Milpitas, California.United States$225M
  2. TigerGraphTigerGraph is an enterprise-grade AI infrastructure and graph analytics software company founded in 2012 and based in Redwood CityUnited States$63M
  3. NGD SystemsNGD Systems manufactures the world’s most advanced computational storage drives (CSDs) that allow customers to compute anywhere.United States$32M
  4. Folio PhotonicsFolio Photonics is a technology company based in Solon, Ohio, founded in 2012.United States$26M
  5. Distributed SpectrumDistributed Spectrum is a defense technology company founded in 2020 by Harvard engineering students Alex Wulff, Ben Harpe, and Isaac Struhl.United States$25M
  6. DataChatDataChat is an information technology company that offers conversational intelligence platform.United States$25M
  7. Ikigai LabsIkigai helps analysts and operations teams automate data-intensive business, finance, analytics, and supplychain operations.United States$25M
  8. LiminalLiminal operates as a battery manufacturing intelligence provider that utilizes data and analytics.United States$22M

Hardware & Electronics

54 startups · $98M raised

  1. QC WareBringing quantum computing power to the enterprise.United States$32M
  2. Sonera MagneticsSonera develops a technology for high-performance, non-invasive brain-computer interfaces to democratize access to the brain.United States$11M
  3. PseudolithicPseudolithIC is a semiconductor company based in Santa Barbara, specializing in heterogeneous integration for high-performance RF United States$6.0M
  4. CubeWorksCubeWorks is a deep-tech Internet of Things (IoT) company based in Ann Arbor, Michigan.United States$5.1M
  5. Momentum OpticsMomentum Optics develops a novel optical lens for the optical components industry.United States$4.3M
  6. BeamlinkBeamlink is a social enterprise that provides Internet access to people living in disaster zones and other remote areas.United States$2.5M
  7. AM BatteriesAM Batteries is a clean energy technology company based in Billerica, Massachusetts, founded in 2016 by Yan Wang and Heng Pan.United States$2.2M
  8. Tagore TechnologyTagore Technology is a semiconductor company that manufactures radio frequency products.United States$2.0M

Energy

53 startups · $2.2B raised

  1. SSILAUnited States$1.7B
  2. Nth CycleNth Cycle is a metal processing technology company working with battery recyclers and miners to recover production-grade critical minerals.United States$137M
  3. Solid PowerSolid Power is a developer of all-solid-state battery cells that provide enhancements over traditional lithium-ion batteries.United States$130M
  4. Coreshell TechnologiesCoreshell Technologies is a nanotechnology company that is a developer of nanolayer coating technology for rechargeable batteries.United States$54M
  5. Swift SolarSwift Solar is a U.S.-based solar technology company founded in 2017, emerging from collaborations with MIT, Stanford University, United States$27M
  6. XL BatteriesXL Batteries develops a technology platform to reduce waste formation.United States$21M
  7. Darcy SolutionsDarcy Solutions is a renewable energy equipment manufacturer and geothermal technology company founded in 2018.United States$15M
  8. Elementium MaterialsElementium Materials is a technology company.United States$13M

Cleantech

46 startups · $1.1B raised

  1. HHeirloomUnited States$203M
  2. Great Lakes ReNEWGreat Lakes ReNEW is a partnership of more than 50 institutions, including universities, technology firms, and government.United States$160M
  3. AmberBuilt by a collective of artisans, Amber functions as an integrated hub with multidisciplinary global locations.Australia$148M
  4. Skyven TechnologiesSkyven Technologies is an energy-as-a-service company with a mission to decarbonize industrial process heat.United States$145M
  5. TwelveTwelve offers smart payment solutions such as software modules, links, ordering solutions, internet solutions, communication & sponsorship.United States$117M
  6. Turntide TechnologiesTurntide Technologies develops an electric motor system designed to drive down energy consumption.United States$80M
  7. ZwitterCoZwitterCo is a leader in advanced membrane solutions for industrial and agricultural water treatment, founded in 2018 as a spinoutUnited States$58M
  8. Altaeros EnergiesAltaeros Energies develops airborne wind turbine to produce abundant, low cost, renewable energy.United States$42M

Manufacturing

46 startups · $162M raised

  1. Alloy EnterprisesAlloy Enterprises operates as industry disruptors looking to tackle inefficiencies in conventional manufacturing.United States$26M
  2. Cision VisionCision Vision is a developer and seller of imaging medical devices.United States$22M
  3. MembrionMembrion is a manufacturer of ultra-low cost, high performance ion exchange membranes.United States$22M
  4. VoltaiqVoltaiq is a technology company focused on Enterprise Battery Intelligence (EBI) and advanced analytics software for the battery-pUnited States$14M
  5. Monogram OrthopedicsMonogram Orthopaedics is a producer of surgical robotic equipment.United States$13M
  6. NuMatNumat Technologies is a leader in the development and commercialization of metal-organic frameworks (MOFs), innovative materials kUnited States$12M
  7. Infinite CoolingInfinite Cooling is a renewables and environment company that specializes in wastewater management and recycling.United States$12M
  8. Adaptive3DAdaptive3D is a U.S.-based company specializing in additive manufacturing materials, particularly premium polymer resins and speciUnited States$5.1M

Advanced Manufacturing

43 startups · $168M raised

  1. unspunUnspun is a fashion-tech company creating 3D weaving technology for apparel.United States$42M
  2. RRRealtime RoboticsUnited States$33M
  3. InkbitInkbit is an additive manufacturing company founded in 2017 as a spinout from MIT's Computer Science and Artificial Intelligence Laboratory.United States$31M
  4. FortifyFortify is a mobile application and technical tool that helps to find healing and recovery from sexual compulsivity.United States$15M
  5. Chromatic 3D MaterialsChromatic is inventing 3D printing materials with the durability to meet the requirements for finished manufactured goods.United States$6.5M
  6. NANOCHONNanochon is a Washington, DC-based medical device and biotechnology company founded in 2016 by Dr.United States$4.1M
  7. 3DEO3DEO is an American manufacturing company that specializes in metal additive manufacturing, also known as metal 3D printing.United States$3.5M
  8. MindTraceMindTrace is a neurosurgical software company based in Pittsburgh, Pennsylvania, founded in 2020 as a spin-off from Carnegie MelloUnited States$3.3M

Edtech

40 startups · $58M raised

  1. ApprenNetApprenNet provides web and mobile platform to enable practice-based learning for both soft skills and hands-on technical training.United States$8.2M
  2. MWMount Wachusett Community CollegeMount Wachusett Community College provides students with various learning opportunities and services.United States$7.1M
  3. Institute for Integrative and Innovative ResearchI3R partners with various organizations to drive positive societal impact through cutting-edge research and innovation.United States$4.9M
  4. TriseumTriseum is an information technology company that offers game based learning, computer gaming, e-learning, and education technology.United States$4.5M
  5. BRIOBrio provides recritment services to the biopharma, pharmaceutical, device, and CRO industries.Romania$3.4M
  6. RoboKindRobokind focuses on making robotics and artificial intelligence accessible to all humans.Germany$3.3M
  7. LaunchPad CentralLaunchPad Central is an innovation management software.United States$2.4M
  8. ZeroUIZeroUI is the developer of an experiential E-learning platform Ziro Studio (www.zirostuidio.com), It is an online interactive 3D pUnited States$2.0M

How this map is made. Every startup here has raised money in a round we track that names National Science Foundation as an investor, the first in 2010. Each sits under its main sector, read from its rounds, and each sector shows its best-funded first; sectors with fewer than three companies are left off. Rebuilt nightly; updated 15 November 2026.

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