Who invested in Spero Therapeutics?
Spero Therapeutics's investors include SR One, National Science Foundation, RA Capital Management, Atlas Partner and Google Ventures, and 16 more on record.

United States · Funded startup
Funding summaryUpdated 26 Oct 2026
$199Mraised across 6 rounds since 2010, from 7 sources
Each circle is a round, placed by date and sized by amount. The line above is the running total.
Reported by HealthCare Royalty and 1 other
Source recordedSEC filing: $9.0M sold, first sale Nov 2022
Reported by FinSMEsSEC filing: $43M sold, first sale Mar 2017
From a historical funding record
From Spero Therapeutics's own website and the SEC filings it signed: 10 on the team.
On the board, as filediJohn C. PottageKathleen C. TregoningMilind DeshpandePatrick E. VinkScott C. Jackson
The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.
Spero Therapeutics's investors include SR One, National Science Foundation, RA Capital Management, Atlas Partner and Google Ventures, and 16 more on record.
Spero Therapeutics has raised $199M across 6 rounds since 2010. One round did not disclose an amount, so the total is a floor.
Spero Therapeutics's most recent round was a Debt of $105M in Jul 2026.
Its most recent round, $105M in Jul 2026, is also its largest on record.
Spero Therapeutics's first round on record, in Jan 2010, was backed by Atlas Partner.
Spero Therapeutics's latest named round is a Debt, in Jul 2026.
Spero Therapeutics is based in the United States.
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