United States · Funded startup

Who invested in Spero Therapeutics

6 rounds we have observed, with the 21 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

BiotechHealthcare

Raised 4 months ago

Funding summaryUpdated 26 Oct 2026

$199Mraised across 6 rounds since 2010, from 7 sources

$3.0MSeries A$30MSeries A$52MSeries C$9.0MRound$105MDebt
Latest round
Debt, $105MJul 2026
Step-upi
11.7×
Investors
21
See who backed them

The funding story

Each circle is a round, placed by date and sized by amount. The line above is the running total.

201020132016201920222025
?Seed$3.0MSeries A$30MSeries A$52MSeries C$9.0MRound$105MDebt
First round
Seed
Jan 2010
Biggest round
$105M
Debt · Jul 2026
Usual gap between rounds
3.8 years
the median of 5

The rounds

  1. Jul 2026
  2. Sept 2022
    Round$9.0M3 new1 returning

    Source recordedSEC filing: $9.0M sold, first sale Nov 2022

  3. Mar 2017
    Series C$52M8 new1 returning

    Reported by FinSMEsSEC filing: $43M sold, first sale Mar 2017

  4. Jun 2015
  5. Apr 2014
    Series A$3.0M1 returning

    From a historical funding record

  6. Jan 2010
    SeedAmount undisclosed1 new

    From a historical funding record

Founders and team

From Spero Therapeutics's own website and the SEC filings it signed: 10 on the team.

  • Esther RajaveluPresident and Chief Executive Officer
  • John RaymondSenior Vice President of Finance and Business Operations
  • Sheila FinanSenior Vice President Controller
  • Timothy C. KeutzerChief Operating Officer
  • Ankit MahadeviaExecutive Officer, Directori
  • Cynthia C. SmithCompensation Committee Chair
  • Frank E. ThomasChairman of the Board; Audit Committee Chair
  • Kamal C. HamedExecutive Officeri
  • Satyavrat ShuklaExecutive Officeri
  • Tamara C. JosephExecutive Officeri

On the board, as filediJohn C. PottageKathleen C. TregoningMilind DeshpandePatrick E. VinkScott C. Jackson

Who was in which round

The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.

Everyone who backed them

SR OneCorporate VC4rounds
RA Capital ManagementPrivate equity2rounds
Atlas PartnerVC firm2rounds
Google VenturesCorporate VC1round
Atlas VentureVC firm1round
GlaxoSmithKlineVC firm1round
AtlasPrivate equity1round
The Kraft GroupInvestment firm1round
Kraft GroupInvestment firm1round
MRL FundCompany1round
HealthCare RoyaltyInvestment firm1round
GV/ RA Capitalno record of our own yet1round
Limitedno record of our own yet1round
Merck Research Venturesno record of our own yet1round
Rock Springsno record of our own yet1round

Missing a round, or an investor who was in one? Tell us.

Quick answers about Spero Therapeutics

Who invested in Spero Therapeutics?

Spero Therapeutics's investors include SR One, National Science Foundation, RA Capital Management, Atlas Partner and Google Ventures, and 16 more on record.

How much has Spero Therapeutics raised?

Spero Therapeutics has raised $199M across 6 rounds since 2010. One round did not disclose an amount, so the total is a floor.

When did Spero Therapeutics last raise?

Spero Therapeutics's most recent round was a Debt of $105M in Jul 2026.

What was Spero Therapeutics's biggest round?

Its most recent round, $105M in Jul 2026, is also its largest on record.

Who backed Spero Therapeutics first?

Spero Therapeutics's first round on record, in Jan 2010, was backed by Atlas Partner.

What stage is Spero Therapeutics at?

Spero Therapeutics's latest named round is a Debt, in Jul 2026.

Where is Spero Therapeutics based?

Spero Therapeutics is based in the United States.

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