Sector portfolio · Government fund · United States

National Science Foundation's Biotech portfolio

National Science Foundation has backed 250 Biotech startups in rounds we track, $2.0B between them, shown by the stage each has reached. The best-funded is Spero Therapeutics.

250startups backed
5stages
$2.0Braised between them
Stage not reportedbiggest stage

National Science Foundation's whole portfolioNational Science Foundation's profile

Stage not reported

186

+162 more

Series A

23

Pre-seed and seed

22

Series B

11

Series C and later

8

Segment by segment

Stage not reported

186 startups · $426M raised

  1. Mission BioMission Bio is a biotechnology company based in South San Francisco, founded in 2014.United States$40M
  2. BiomasonBiomason, Inc.United States$37M
  3. KytopenKytopen is a biotechnology company based in Cambridge, Massachusetts, founded in 2017 as an MIT spin-out.United States$35M
  4. Vaxess TechnologiesVaxess Technologies engages in developing biomedical innovations with a focus on improving access to vaccines.United States$23M
  5. SonavexSonavex is a developer of an imaging technology designed to visualize and quantify critical data to detect anastomotic blood clots.United States$20M
  6. EradivirEradivir is a clinical-stage biotechnology company based in West Lafayette, Indiana, founded in 2020.United States$20M
  7. Primrose BioPrimrose Bio is a biotechnology company that focuses on discovery, development, and manufacturing of new molecules.United States$17M
  8. PSPrescient SurgicalPrescient Surgical, Inc.United States$16M

Series A

23 startups · $640M raised

  1. Caribou BiosciencesCaribou Biosciences is a biotechnology company that develops CRISPR technologies and allogenic cell therapies for oncology.United States$139M
  2. ProLynxProlynx is a clinical-stage biotechnology company based in the San Francisco Bay Area, founded in 2009.United States$70M
  3. Think BioscienceThink Bioscience is a synthetic biology company located in Boulder, Colorado.United States$55M
  4. Manus BioManus Bio develops an advanced fermentation technology to recreate plant processes in microorganisms.United States$52M
  5. AzitraAzitra is a clinical-stage medical dermatology company developing microbiome-based novel therapeutics to treat skin conditions and diseases.United States$49M
  6. Nabla BioNabla Bio is a biotechnology company founded in 2020 that focuses on developing selective and functional drugs for previously undrUnited States$37M
  7. Phase ScientificPhase Scientific provides tool for health care industry.Hong Kong SAR China$34M
  8. GenEditGenEdit develops next generation therapeutics for genetic diseases through safe and efficient CRISPR/Cas9 delivery.United States$33M

Pre-seed and seed

22 startups · $66M raised

  1. Amphix BioAmphix Bio is a biotechnology company that develops regenerative medicine therapies using a platform of supramolecular therapeutic peptides.United States$13M
  2. iMicrobesiMicrobes, officially known as Industrial Microbes, Inc., is a synthetic biology company based in Alameda, California.United States$10M
  3. Abalone BioAbalone Bio is a preclinical-stage biotechnology company based in Emeryville, California, founded in 2017.United States$7.6M
  4. Partillion BiosciencePartillion Bioscience is an early-stage life science company developing a functional single-cell analysis platform.United States$7.1M
  5. UNCAGED InnovationsUNCAGED Innovations is a biomaterials company combining the power of nature and technology to reimagine leather.United States$5.6M
  6. Auxilium HealthAuxilium Health is creating low-cost, smart biomaterials for difficult-to-heal wounds.United States$4.5M
  7. VerImmuneVerImmune is a biotechnology company founded in 2019, focused on developing innovative cancer immunotherapies.United States$4.5M
  8. dfusiondfusion, a team of scientists and innovators, develops technology to promote evidence-based, health-related behavioral changes.United States$2.8M

Series B

11 startups · $385M raised

  1. Lucira HealthLucira Health is a biotechnology company that offers disposable test kits to detect RNA and DNA of infectious diseases.United States$95M
  2. GRO BiosciencesGRO Biosciences, also known as GRObio, is a biotechnology company based in Cambridge, Massachusetts, founded in 2016.United States$87M
  3. BreezeBioBreezeBio, Inc., based in South San Francisco, California, is a biotechnology company founded in 2016 by Dr.United States$60M
  4. LygosLygos provides biotechnology solutions for today’s renewable chemical challenges.United States$35M
  5. NanopathNanopath Inc.United States$25M
  6. SQZ BiotechSQZ Biotech features a cell engineering technology designed to deliver a diverse set of materials into patient cells.United States$23M
  7. HealthMyneHealthMyne provides clinicians with evidence-based imaging insights and solutions.United States$20M
  8. DMC BiotechnologiesDMC Biotechnologies produces bio-based chemicals using fermentation.United States$19M

Series C and later

8 startups · $453M raised

  1. Spero TherapeuticsSpero Therapeutics develops therapeutics for treatment of gram-negative infections.United States$199M
  2. CoreMapCoreMap is a medical device company founded in 2016, focused on advanced diagnostic technology for electrophysiologists.United States$57M
  3. Terrestrial BioTerrestrial Bio engages in developing biomedical innovations with a focus on improving access to vaccines.United States$50M
  4. Parse BiosciencesParse Biosciences is a biotechnology startup company that develops single-cell sequencing kit solutions for researchers.United States$50M
  5. Symic BioSymic Bio is a biopharmaceutical company based in San Francisco, California, founded in 2012.United States$41M
  6. ANEUVOANEUVO, based in Los Angeles, California, is a bioelectronic medical device company focused on developing innovative therapies forUnited States$22M
  7. Maui ImagingMAUI Imaging is a medical imaging company dedicated to enhancing ultrasound technology.United States$21M
  8. Halo LabsUnited States$13M

How this map is made. Every startup here works in Biotech and has raised money in a round we track that names National Science Foundation as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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