Sector portfolio · Government fund · United States

National Science Foundation's AI portfolio

National Science Foundation has backed 118 AI startups in rounds we track, $1.9B between them, shown by the stage each has reached. The best-funded is Samay.

118startups backed
5stages
$1.9Braised between them
Stage not reportedbiggest stage

National Science Foundation's whole portfolioNational Science Foundation's profile

Stage not reported

79

+55 more

Pre-seed and seed

22

Series A

8

Series B

7

Series C and later

2

Segment by segment

Stage not reported

79 startups · $973M raised

  1. SamaySamay Health, founded in 2018 by Dr.United States$250M
  2. IAMBICAI-driven, precision-fit footwear.United States$167M
  3. Allen Institute for Artificial IntelligenceAllen Institute for Artificial Intelligence (AI2) is an artificial intelligence research institute and start-up incubator.United States$152M
  4. ModeMODE is driven to help organizations leverage their data to improve operations, safety, & efficiencies through the use of IoT & AIUnited States$70M
  5. FlexComputeFlexcompute is a Boston-based software company founded in 2015 that specializes in cloud-based multi-physics simulation tools.United States$53M
  6. Citrine InformaticsCitrine Informatics provides an informatics platform that transforms chemicals development through AI embedded in smart data infrastructure.United States$33M
  7. AutonomysAutonomys is a private company based in San Francisco, founded in 2018.United States$33M
  8. Ambi RoboticsAmbi Robotics is an AI and robotics company focused on automation solutions for high-volume e-commerce, parcel, postal, and third-United States$32M

Pre-seed and seed

22 startups · $205M raised

  1. EEdenUnited States$104M
  2. Talus BioTalus Bio is a drug discovery biotech startup working on drug development for gene regulators.United States$22M
  3. AtomAtom Bodies is a technology company focused on integrating artificial intelligence with the human body.Japan$22M
  4. ProximalProximal is a studio for creating learning environments in the virtual space.United States$15M
  5. New Equilibrium BiosciencesNew Equilibrium Biosciences is a biotechnology and drug-discovery company based in Boston, Massachusetts, with a presence in Brussels.United States$10M
  6. KelvinKelvin is an energy management and electrification platform for radiator-heated buildings.France$5.4M
  7. Semiotic AISemiotic AI is building automated decision-making tools for decentralized markets on the blockchain.United States$5.0M
  8. Yotta LabsBuilding the GPU Cloud for efficient ML with heterogeneous hardware and cross-cloud orchestrationUnited States$3.5M

Series A

8 startups · $218M raised

  1. KintsugiKintsugi detects signs of clinical depression and anxiety using machine learning and voice biomarkers.United States$42M
  2. QuintessentQuintessent is a Santa Barbara start-up that commercializes quantum dot-based lasers and photonic integrated circuits.United States$40M
  3. UUnderstoryUnited States$40M
  4. ExostellarWe help enterprise companies achieve cloud optimizations and cost reductions without service interruptions.United States$26M
  5. HEN TechnologiesHEN Technologies is a deep-tech company located in Hayward, California, focused on modernizing fire prevention and response.United States$20M
  6. PrenosisPrenosis Inc.United States$20M
  7. DDeepScaleUnited States$19M
  8. Tierra BiosciencesTierra Biosciences is a synthetic biology company based in San Leandro, California, founded in 2015.United States$11M

Series B

7 startups · $378M raised

  1. VVITALCanada$105M
  2. AvicenaAvicena is a developer of medical devices and algorithms used to easily assess cardiovascular health.United States$65M
  3. ClincClinc is a conversational AI platform that enables enterprises to build human-in-the-room level, next-gen, virtual assistants.United States$58M
  4. CHCaption HealthCaption Health is a medical company that uses artificial intelligence (AI) to interpret ultrasound exams.Australia$53M
  5. GrayMatter RoboticsGrayMatter Robotics (GMR) is an innovative AI-powered robotics company based in Los Angeles, California, with a significant faciliUnited States$45M
  6. DrishtiDrishti is a provider of AI-powered video analytics technology that gives visibility and insights for manual assembly line improvement.United States$35M
  7. InsightFinderInsightFinder is a software company that provides monitoring and predictive analytics services for IT operations.United States$17M

Series C and later

2 startups · $139M raised

  1. ElucidElucid enables precision medicine for cardiovascular disease by applying A.I to medical image analysis validated against true biology.United States$92M
  2. AffectivaAffectiva is a developer of an emotion-recognition software designed to analyze subtle facial and vocal expressions.United States$48M

How this map is made. Every startup here works in AI and has raised money in a round we track that names National Science Foundation as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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