United States · 
What does SR One invest in?
SR One invests most often at Series B and Series A (65% of the rounds on record), in sectors such as Telehealth, Health-tech and Well-being.
SR One highlights
- 01
12 cheques in the last 12 months
- 02
Mostly Series B and Series A: 65% of its rounds
- 03
Sole investor in 5 rounds, median $1.5M
- 04
7 exits from the portfolio
What they do
A biotechnology venture capital firm, partnering with founders and entrepreneurs to translate innovative science into medicines.From their own website
- Type
- Corporate VC (from a list, unverified)
- Cheque size
- Not stated
- Stages
- SeedSeries ASeries BGrowthPre-IPO
- Sectors
- TelehealthHealth-techWell-being
- Based in
- San Francisco, United States
- Cold pitches
- Not stated
The record
Every round we can evidence, newest first139 appearances
- 2026
11 rounds
- Oct
- Jul
- Jul
- Jul
- Jul
- Apr
- Mar
- Jan
- Jan
- Jan
- Jan
- 2025
13 rounds
- Dec
- Oct
- Oct
- Oct
- Sept
- Sept
- Sept
- Sept
- Jun
- May
- May
- Feb
- Jan
- 2024
9 rounds
- Dec
- Dec
- Sept
- Aug
- Jul
- Jul
- Jul
- May
- Jan
- 2023
2 rounds
- Nov
- May
- 2022
5 rounds
- Dec
- Sept
- Jun
- Jun
- Jan
An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.
The team
Named by the firm itself, on a filing, its Form ADV or its company registration5 named
JCJames Chalmers MacadamCFOiForm ADV
MFMatthew FoyPartner of GPiFiling they signed
RDRajeev DadooLimited Partner; Managing Partner; COOiForm ADV
SOSasha Oshrine KeoughCCOiForm ADV
SJSimeon John GeorgeManaging Member of the Ultimate Managing MemberiFiling they signed
We also hold 17 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.
What the register says
From the firm's own filings with the SEC, which it must file accurately by law
$2.4Bassets it managesOct 2026
Registeredinvestment adviserfull reporting to the SEC
- Legal name
- SR ONE Capital Management, LP
- SEC number
- CRD 306361
Funds on its Form ADV
17 private funds, $1.6B in gross assets · filed Jul 2024
- SR One Capital Fund II Aggregator, L.P.Private equity69 investors$580M
- SR One Capital Fund I Aggregator, L.P.Private equity34 investors$505M
- SR One Capital Opportunities Fund I, L.P.Private equity7 investors$203M
- AMZL, L.P.Private equity2 investors$150M
- SR One Co-Invest II, LLCPrivate equity2 investors$65M
- SR One Co-Invest III, LLCPrivate equity2 investors$18M
- SR One Co-Invest IV, LLCPrivate equity2 investors$18M
- SR One Co-Invest XI, LLCPrivate equity5 investors$15M
- SR One Co-Invest IV-A, LLCPrivate equity4 investors$11M
- SR One Co-Invest VI, LLCPrivate equity2 investors$5.5M
And 7 more on the filing.
Who backs their funds
1 LP on record in SR One's funds
- Committed
- $841M
- Funds
- 4
- Vintages
- 2023 to 2025
The institutions that put money into its funds, which the firm then invests in companies.Source: the pension's own report, latest Mar 2026.
California Public Employees' Retirement System (CalPERS)4 funds$841M
Fund Vintage Committed SR One Capital Fund III 2025 $79M AMZL 2023 $600M SR One Capital Fund II-A 2023 $90M SR One Capital Opportunities Fund I 2023 $72M
Exits from the portfolio
Companies it backed that were later bought or listed7 in all
Alios BioPharmaBought by Johnson & Johnson$1.8BSept 2014
iPierianBought by Bristol-Myers Squibb$175MApr 2014
NuPatheBought by Endo Health Solutions$105MDec 2013
Semprus BioSciencesBought by Teleflex$30MJun 2012
NuPatheListedUndisclosedAug 2010
AblynxListedUndisclosedNov 2007
An exit counts when it came after the firm's first round in the company. From historical deal records.