United States · Investor

Casdin Capital

Last cheque observed Oct 2026; 104 cheques on record.

Deploying nowNew fund $234M, Nov 2021VC firm

SeedSeries ASeries BHealthHealthier LivingDigital-health

Deploying now
50%of best year8cheques in 12 months, 104 on record
Since the last cheque6days00hrs00min00sec
Median round$65MCheque size, as they say$100K – $5.0MRounds led1 of 104Sole investor5 roundsExits2 from the portfolioMostly inUnited States, 90%
Pitch Casdin Capital

Casdin Capital highlights

  1. 01

    8 cheques in the last 12 months

  2. 02

    Mostly Series B and Series A: 69% of its rounds

  3. 03

    Sole investor in 5 rounds, median $8.1M

  4. 04

    2 exits from the portfolio

What they do

Filed 2 private fund offerings with the SEC, the most recent in 2021-11From their own website
Type
VC firm (from a list, unverified)
Cheque size
$100K – $5.0M as they say
Stages
SeedSeries ASeries BGrowthPre-IPO
Sectors
HealthHealthier LivingDigital-health
Based in
New York, United States
Cold pitches
Not stated

The record

Every round we can evidence, newest first104 appearances

  1. 2026

    6 rounds

  2. Oct
    Bolt BiotherapeuticsUS · Pulse 2.0$120MWith 11 others
  3. Jun
    City TherapeuticsSeries B · US · Ventureburn$100MWith 8 others
  4. Jun
    4D Molecular TherapeuticsDebt · US$200MWith 3 others
  5. Apr
    Revolution MedicinesUS$1.5BWith 2 others
  6. Jan
    ApellaSeries A · US · Vensana Capital$80MWith 2 others
  7. Jan
    Foghorn TherapeuticsUS$50MWith 3 others
  8. 2025

    13 rounds

  9. Dec
    Contineum TherapeuticsUS$99MWith 3 others
  10. Nov
    4D Molecular TherapeuticsUS$100MWith 2 others
  11. Oct
    OctaveVenture · USUndisclosedWith 3 others
  12. Aug
    CANbridge Pharmaceuticals$13MWith 3 others
  13. Aug
    BbotUS$261MWith 3 others
  14. Aug
    Prime MedicineUS$5.0MWith 4 others
  15. Jul
    Auron TherapeuticsVenture · USUndisclosedWith 5 others
  16. Jul
    AbsciUS$50MWith 3 others
  17. May
    A2 BiotherapeuticsGrant · US$300KWith 1 other
  18. Apr
    DeepcellVenture · USUndisclosedWith 4 others
  19. Jan
    Leyden LabsNL · Silicon Canals$70MWith 9 others
  20. Jan
    Umoja BiopharmaSeries C · US$100MWith 6 others
  21. Jan
    Amplo BiotechnologyGrant · US$2.9MWith 1 other
  22. 2024

    15 rounds

  23. Dec
    Xcell BiosciencesVenture · US$1.4MWith 1 other
  24. Dec
    MeiogenixVenture · FRUndisclosedWith 4 others
  25. Sept
    ArzedaGrowth · US · Firms' own news pages$38MWith 9 others
  26. Sept
    Genome MedicalSeries D · US$75MWith 6 others
  27. Sept
    Relay TherapeuticsUS$200MWith 5 others
  28. Aug
    Molecular AssembliesGrant · US$4.0MWith 3 others
  29. Aug
    IdrxSeries B · US$120MWith 3 others
  30. Jul
    TMRW Life SciencesSeries D · US$28MWith 3 others
  31. Jul
    Vanqua BioVenture · US$45MWith 3 others
  32. Jun
    Notch TherapeuticsVenture · CA$16MWith 2 others
  33. May
    Genomic LifeVenture · US$10MSole investor
  34. Apr
    CerevanceSeries B · US$47MWith 3 others
  35. Apr
    Gritstone bioUS$33MWith 3 others
  36. Jan
    Remix TherapeuticsVenture · US$60MWith 4 others
  37. Jan
    Voyager TherapeuticsUS$100MWith 3 others
  38. 2023

    7 rounds

  39. Dec
    ExscientiaGrant · GB$2.3MWith 4 others
  40. Jun
    Scribe BiosciencesVenture · USUndisclosedWith 1 other
  41. Apr
    Orbital TherapeuticsSeries A · US$270MWith 4 others
  42. Apr
    Function OncologySeries A · US$28MWith 3 others
  43. Mar
    Flare TherapeuticsSeries B · US$123MWith 3 others
  44. Mar
    Generation BioUS$76MWith 3 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

The team

Named by the firm itself, on a filing, its Form ADV or its company registration5 named

AFAlexandria FiskChief Operating OfficeriForm ADV
ACAngelo CrupiChief Compliance OfficeriForm ADV
EDEli D CasdinManaging Member of the General PartneriFiling they signed
LJLawrence Jude CanzoneriChief Financial OfficeriForm ADV
SMSteven Michael GiordanoGeneral CounseliForm ADV

We also hold 21 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

What the register says

From the firm's own filings with the SEC, which it must file accurately by law

$2.9Bassets it managesOct 2026
Registeredinvestment adviserfull reporting to the SEC
Legal name
Casdin Capital, LLC
SEC number
CRD 169579

Funds on its Form ADV

6 private funds, $2.6B in gross assets · filed Mar 2024

Hedge 3Private equity 2Venture 1

  1. Casdin Partners Master Fund, L.P.Hedge563 investors$1.9B
  2. Casdin Private Growth Equity Fund II, L.P.Private equity226 investors$402M
  3. Casdin Private Growth Equity Fund, L.P.Private equity175 investors$243M
  4. Casdin Venture Opportunities Fund, L.P.Venture46 investors$29M
  5. Casdin Partners FO1 - MSV, L.P.Hedge2 investors$25M
  6. Casdin Amplify Fund, L.P.Hedge2 investors$14M

Exits from the portfolio

Companies it backed that were later bought or listed2 in all

Foundation MedicineBought by RocheUndisclosedJan 2015
Foundation MedicineListed$108MJul 2013

An exit counts when it came after the firm's first round in the company. From historical deal records.

Who they invest alongside

The investors most often in the same rounds as Casdin Capital. A count of rooms they were both in, not a relationship either has claimed.

Recently backed

The latest companies Casdin Capital put money into.

On podcasts

1 episode naming Casdin Capital in the title.

Quick answers about Casdin Capital

What does Casdin Capital invest in?

Casdin Capital invests most often at Series B and Series A (69% of the rounds on record), in sectors such as Health, Healthier Living and Digital-health.

How active is Casdin Capital?

104 investments on record, 8 of them in the last 12 months, and it led 1. The most recent was in Oct 2026.

What has Casdin Capital invested in recently?

Its most recent investments on record: Bolt Biotherapeutics (Undisclosed round, Oct 2026), City Therapeutics (Series B, Jun 2026) and 4D Molecular Therapeutics (Debt, Jun 2026).

How big are Casdin Capital's cheques?

The median round it joins is $65M. It says it writes cheques of $100K to $5.0M.

Does Casdin Capital lead rounds?

Sometimes: it led 1 of its 104 investments on record (1%).

Where does Casdin Capital invest?

Most of the companies it backs are in the United States (90%).

Is Casdin Capital investing now?

Yes: it is actively investing, with 8 investments in the last 12 months.

Who does Casdin Capital invest alongside?

Most often Redmile Group (13 rounds together), Fidelity (12 rounds together) and Google Ventures (12 rounds together).

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Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it