Top list · San Mateo
Biotech startups in San Mateo
22 biotech startups in San Mateo have raised money in rounds we track. These are the 22 that have raised the most, $1.5B between them.
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Bluejay TherapeuticsBluejay Therapeutics is a private biopharmaceutical company focused on the development of cures for infectious diseases.Bluejay Therapeutics is a private biopharmaceutical company focused on the development of cures for infectious diseases.
Founded 2019San Mateo, United States$182Mlast round May 2024 - 2
Luma HealthLuma Health is a healthcare technology company founded in 2015 and based in San Mateo, California.Luma Health is a healthcare technology company founded in 2015 and based in San Mateo, California.
Founded 2015San Mateo, United States$152Mlast round Nov 2021 - 3
BigHat BiosciencesBigHat Biosciences is a biotechnology company founded in 2019 and based in San Mateo, California.BigHat Biosciences is a biotechnology company founded in 2019 and based in San Mateo, California.
Founded 2019San Mateo, United States$150Mlast round Sept 2026 - 4
Cala HealthCala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013.Cala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013.
Founded 2014San Mateo, United States$150Mlast round Apr 2026 - 5
NotableNotable is an AI-powered health start-up that automates and digitizes every physician-patient interaction.Notable is an AI-powered health start-up that automates and digitizes every physician-patient interaction.
Founded 2017San Mateo, United States$145Mlast round Jul 2026 - 6
AusperBioAusperBio is a clinical-stage biopharmaceutical company dedicated to advancing treatments for hepatitis B virus (HBV) and developing oligonucleotide therapeutics.AusperBio is a clinical-stage biopharmaceutical company dedicated to advancing treatments for hepatitis B virus (HBV) and developing oligonucleotide therapeutics.
Founded 2019San Mateo, United States$113Mlast round Sept 2025 - 7
CARGO TherapeuticsCARGO Therapeutics develops an adoptive cell therapy to benefit patients from potentially curative treatment options.CARGO Therapeutics develops an adoptive cell therapy to benefit patients from potentially curative treatment options.
Founded 2019San Mateo, United States$110Mlast round May 2024 - 8
EpiBiologicsEpiBiologics is a biotechnology company based in San Mateo, California, founded in 2022.EpiBiologics is a biotechnology company based in San Mateo, California, founded in 2022.
Founded 2022San Mateo, United States$107Mlast round Jan 2026 - 9
Kivu BioscienceAs a company focused on rapidly advancing next generation transformative assets, we leverage our expertise to efficiently progress programs to clinical proof of concept.As a company focused on rapidly advancing next generation transformative assets, we leverage our expertise to efficiently progress programs to clinical proof of concept.
Founded 2024San Mateo, United States$92Mlast round Oct 2024 - 10
Vivace TherapeuticsVivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway.Vivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway.
Founded 2014San Mateo, United States$75Mlast round Mar 2025 - 11
Route 92 MedicalRoute 92 Medical is a medical device company developing a catheter to treat stroke.Route 92 Medical is a medical device company developing a catheter to treat stroke.
Founded 2015San Mateo, United States$63Mlast round Apr 2026 - 12
Evidation HealthWe enable and empower everyone to participate in better health outcomes.We enable and empower everyone to participate in better health outcomes.
Founded 2012San Mateo, United States$61Mlast round Aug 2018 - 13
Sagimet BiosciencesSagimet Biosciences is a biotechnology company that focuses on developing novel therapeutics to treat important diseases.Sagimet Biosciences is a biotechnology company that focuses on developing novel therapeutics to treat important diseases.
Founded 2007San Mateo, United States$25Mlast round Aug 2019 - 14
LumiataLumiata was a healthcare-focused artificial intelligence company founded in 2013 in San Mateo, California.Lumiata was a healthcare-focused artificial intelligence company founded in 2013 in San Mateo, California.
Founded 2013San Mateo, United States$21Mlast round Jul 2018 - 15
SonoMotionSonomotion is a medical device manufacturing company that specializes in providing medical solutions for kidney stones disease.Sonomotion is a medical device manufacturing company that specializes in providing medical solutions for kidney stones disease.
Founded 2014San Mateo, United States$12Mlast round Feb 2025 - 16
Food In-DepthWe do not know enough about what is in our food.We do not know enough about what is in our food.
Founded 2015San Mateo, United States$12Mlast round Feb 2021 - 17
VyncaVynca, also known as VyncaCare, is a healthcare technology company based in San Mateo, California.Vynca, also known as VyncaCare, is a healthcare technology company based in San Mateo, California.
Founded 2014San Mateo, United States$10Mlast round Jun 2019 - 18uLink LabsuLink Labs is a medical device company that specializes in next-generation medical devices innovations.
uLink Labs is a medical device company that specializes in next-generation medical devices innovations.
Founded 2019San Mateo, United States$8.6Mlast round Nov 2025 - 19
Maverix BiomicsMaverix Biomics is a biotechnology and bioinformatics company based in San Mateo, California.Maverix Biomics is a biotechnology and bioinformatics company based in San Mateo, California.
Founded 2012San Mateo, United States$6.0Mlast round Jan 2014 - 20
NuMediiNuMedii, Inc.NuMedii, Inc.
Founded 2008San Mateo, United States$5.5Mlast round Aug 2015 - 21
Bespoke BiotherapeuticsBespoke Biotherapeutics is a biotechnology company that provides engineered B-cell therapeutics.Bespoke Biotherapeutics is a biotechnology company that provides engineered B-cell therapeutics.
Founded 2021San Mateo, United States$256Klast round Jun 2022 - 22
Genobank.ioGenoBank.io is a pioneering company that offers the first anonymous, privacy-preserving DNA test kit utilizing blockchain technology.GenoBank.io is a pioneering company that offers the first anonymous, privacy-preserving DNA test kit utilizing blockchain technology.
Founded 2018San Mateo, United States$50Klast round Oct 2022
San Mateo, United StatesCompanies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
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