Top list · Worldwide

Biotech startups founded in 2021

275 biotech startups founded in 2021 have raised money in rounds we track. These are the 50 that have raised the most, $12B between them, with the United States the most common home.

$12Braised by these 50
275on our record in all
United Statesmost common home
Isomorphic Labsraised the most
  1. 1Isomorphic LabsIsomorphic Labs is a London-based artificial intelligence company focused on transforming the drug discovery process.

    Isomorphic Labs is a London-based artificial intelligence company focused on transforming the drug discovery process.

    Founded 2021London, United Kingdom$3.1Blast round May 2026
  2. 2Retro BiosciencesRetro Biosciences is a biotechnology company based in Redwood City, California, founded in May 2021.

    Retro Biosciences is a biotechnology company based in Redwood City, California, founded in May 2021.

    Founded 2021Redwood City, United States$1.2Blast round May 2026
  3. 3Varda Space IndustriesVarda Space Industries is a private American company based in El Segundo, California, focused on space manufacturing.

    Varda Space Industries is a private American company based in El Segundo, California, focused on space manufacturing.

    Founded 2021El Segundo, United States$438Mlast round Oct 2026
  4. 4Colossal BiosciencesColossal Biosciences is an American biotechnology and genetic engineering company founded in September 2021, recognized as the world's first dedicated de-extinc

    Colossal Biosciences is an American biotechnology and genetic engineering company founded in September 2021, recognized as the world's first dedicated de-extinc

    Founded 2021Dallas, United States$380Mlast round Feb 2026
  5. 5AlumisAlumis is a precision medicine company focused on the discovery, development and treatment of autoimmune disorders.

    Alumis is a precision medicine company focused on the discovery, development and treatment of autoimmune disorders.

    Founded 2021San Francisco, United States$345Mlast round Jan 2026
  6. 6ArriVentArriVent develops pharmaceutical products to cure presently untreatable cancer.

    ArriVent develops pharmaceutical products to cure presently untreatable cancer.

    Founded 2021Pennsylvania Furnace, United States$325Mlast round May 2026
  7. 7ReNAgade TherapeuticsReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease.

    ReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease.

    Founded 2021Cambridge, United States$300Mlast round May 2023
  8. 8Terremoto BiosciencesTerremoto Biosciences is a clinical-stage biotechnology company founded in 2021, focused on covalent drug discovery and development.

    Terremoto Biosciences is a clinical-stage biotechnology company founded in 2021, focused on covalent drug discovery and development.

    Founded 2021South San Francisco, United States$283Mlast round Apr 2026
  9. 9MoonLake ImmunotherapeuticsMoonLake Immunotherapeutics is a clinical-stage biopharmaceuticals company.

    MoonLake Immunotherapeutics is a clinical-stage biopharmaceuticals company.

    Founded 2021Zug, Switzerland$275Mlast round Jun 2026
  10. 10Centessa PharmaceuticalsCentessa Pharmaceuticals is a pharmaceutical company that focuses on drug development to address significant medical needs.

    Centessa Pharmaceuticals is a pharmaceutical company that focuses on drug development to address significant medical needs.

    Founded 2021Cambridge, United States$250Mlast round Nov 2025
  11. 11Odyssey TherapeuticsOdyssey Therapeutics creates precision immunomodulators and oncology medicines for patients with cancer and inflammatory diseases.

    Odyssey Therapeutics creates precision immunomodulators and oncology medicines for patients with cancer and inflammatory diseases.

    Founded 2021Boston, United States$238Mlast round May 2026
  12. 12Matchpoint TherapeuticsMatchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.

    Matchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.

    Founded 2021Cambridge, United States$220Mlast round Oct 2026
  13. 13Tome BiosciencesTome Biosciences is a biotechnology company based in Watertown, MA, focused on advancing programmable genomic integration (PGI) to develop curative cell and gen

    Tome Biosciences is a biotechnology company based in Watertown, MA, focused on advancing programmable genomic integration (PGI) to develop curative cell and gen

    Founded 2021Watertown, United States$213Mlast round Dec 2023
  14. 14Treeline BiosciencesTreeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.

    Treeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.

    Founded 2021Watertown, United States$200Mlast round Sept 2025
  15. 15Upstream BioUpstream Bio focuses on developing an antibody therapy for the treatment of severe asthma.

    Upstream Bio focuses on developing an antibody therapy for the treatment of severe asthma.

    Founded 2021Waltham, United States$200Mlast round Jun 2023
  16. 16Aktis OncologyAktis Oncology is a biotechnology company discovering and developing a novel class of targeted radiopharmaceuticals.

    Aktis Oncology is a biotechnology company discovering and developing a novel class of targeted radiopharmaceuticals.

    Founded 2021Boston, United States$175Mlast round Sept 2024
  17. 17Mariana OncologyMariana Oncology is a biotechnology research industry.

    Mariana Oncology is a biotechnology research industry.

    Founded 2021Watertown, United States$175Mlast round Sept 2023
  18. 18Affini-T TherapeuticsAffini-T Therapeutics is a clinical-stage precision immunotherapy company based in Watertown, Massachusetts.

    Affini-T Therapeutics is a clinical-stage precision immunotherapy company based in Watertown, Massachusetts.

    Founded 2021Watertown, United States$175Mlast round Mar 2022
  19. 19Capstan TherapeuticsCapstan Therapeutics is advancing cell engineering to develop therapeutics for a broad range of diseases.

    Capstan Therapeutics is advancing cell engineering to develop therapeutics for a broad range of diseases.

    Founded 2021San Diego, United States$175Mlast round Mar 2024
  20. 20Tourmaline BioTourmaline Bio is a biotechnology company that develops medicines to treat inflammatory and immune diseases in patients.

    Tourmaline Bio is a biotechnology company that develops medicines to treat inflammatory and immune diseases in patients.

    Founded 2021New York, United States$173Mlast round Jan 2024
  21. 21CaidyaCaidya is a clinical research organization that provides personalized solutions for various therapeutic areas.

    Caidya is a clinical research organization that provides personalized solutions for various therapeutic areas.

    Founded 2021Raleigh, United States$165Mlast round Jan 2025
  22. 22Nuvig TherapeuticsNuvig Therapeutics is advancing innovative and transformational therapies that are designed to induce natural mechanisms to restore immune.

    Nuvig Therapeutics is advancing innovative and transformational therapies that are designed to induce natural mechanisms to restore immune.

    Founded 2021Redwood City, United States$161Mlast round Dec 2024
  23. 23AIRNAAIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.

    AIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.

    Founded 2021Cambridge, United States$155Mlast round Apr 2025
  24. 24Bitterroot BioBitterroot Bio, Inc.

    Bitterroot Bio, Inc.

    Founded 2021Palo Alto, United States$145Mlast round Jun 2023
  25. 25Zura BioZura Bio is a clinical-stage, multi-asset biotechnology company.

    Zura Bio is a clinical-stage, multi-asset biotechnology company.

    Founded 2021Henderson, United States$144Mlast round Feb 2026
  26. 26AAVantgarde BioAAVantgarde Bio is developing gene therapies for inherited retinal disorders.

    AAVantgarde Bio is developing gene therapies for inherited retinal disorders.

    Founded 2021Milano, Italy$141Mlast round Nov 2025
  27. 27AcceraAccera is a Danish construction company based in Brøndby, founded in 2021.

    Accera is a Danish construction company based in Brøndby, founded in 2021.

    Founded 2021Brondbyvester, United States$139Mlast round Oct 2013
  28. 28Chroma MedicineChroma Medicine, founded in 2021 and based in Boston/Cambridge, Massachusetts, is a biotechnology company focused on developing epigenetic medicines for genetic

    Chroma Medicine, founded in 2021 and based in Boston/Cambridge, Massachusetts, is a biotechnology company focused on developing epigenetic medicines for genetic

    Founded 2021Boston, United States$135Mlast round Feb 2023
  29. 29ARTBIOARTBIO is a clinical-stage biotechnology company founded in 2021, focused on developing alpha radioligand therapies for targeted cancer treatment.

    ARTBIO is a clinical-stage biotechnology company founded in 2021, focused on developing alpha radioligand therapies for targeted cancer treatment.

    Founded 2021Cambridge, United States$132Mlast round Jul 2025
  30. 30SonoTheraSonoThera is a biotechnology company based in South San Francisco that focuses on developing ultrasound-guided, nonviral gene therapies.

    SonoThera is a biotechnology company based in South San Francisco that focuses on developing ultrasound-guided, nonviral gene therapies.

    Founded 2021South San Francisco, United States$125Mlast round Jun 2026
  31. 312seventy bio2seventy bio is an immuno-oncology cell therapy company that discovers and develops cancer therapies.

    2seventy bio is an immuno-oncology cell therapy company that discovers and develops cancer therapies.

    Founded 2021Cambridge, United States$125Mlast round Feb 2023
  32. 32Bonum TherapeuticsBonum Therapeutics creates a technology platform to treat a wide range of diseases.

    Bonum Therapeutics creates a technology platform to treat a wide range of diseases.

    Founded 2021Seattle, United States$120Mlast round Apr 2026
  33. 33Synnovation TherapeuticsSynnovation Therapeutics is a clinical-stage biotechnology company based in Wilmington, Delaware, founded in 2021.

    Synnovation Therapeutics is a clinical-stage biotechnology company based in Wilmington, Delaware, founded in 2021.

    Founded 2021Wilmington, United States$102Mlast round Dec 2023
  34. 34Amber TherapeuticsAmber Therapeutics is a clinical-stage medical technology company based in London, founded in 2021 as a spinout from the University of Oxford.

    Amber Therapeutics is a clinical-stage medical technology company based in London, founded in 2021 as a spinout from the University of Oxford.

    Founded 2021London, United Kingdom$102Mlast round Mar 2026
  35. 35Context TherapeuticsContext Therapeutics is a clinical-stage biopharmaceutical company.

    Context Therapeutics is a clinical-stage biopharmaceutical company.

    Founded 2021Philadelphia, United States$100Mlast round May 2024
  36. 36OnCusp TherapeuticsOnCusp Therapeutics, Inc.

    OnCusp Therapeutics, Inc.

    Founded 2021New York, United States$100Mlast round Jan 2024
  37. 37Paratus SciencesParatus Sciences is a biotechnology startup founded in 2021, based in New York, NY, with a subsidiary in Singapore.

    Paratus Sciences is a biotechnology startup founded in 2021, based in New York, NY, with a subsidiary in Singapore.

    Founded 2021Boston, United States$100Mlast round Feb 2023
  38. 38InceptiveInceptive is a biotechnology and artificial intelligence company founded in 2021 and based in Palo Alto, California, with additional offices in Berlin and Zurich.

    Inceptive is a biotechnology and artificial intelligence company founded in 2021 and based in Palo Alto, California, with additional offices in Berlin and Zurich.

    Founded 2021Palo Alto, United States$100Mlast round Sept 2023
  39. 39Alethio TherapeuticsAlethio Therapeutics is a preclinical-stage biotechnology company based in Abingdon Science Park near Oxford, UK.

    Alethio Therapeutics is a preclinical-stage biotechnology company based in Abingdon Science Park near Oxford, UK.

    Founded 2021Abingdon, United Kingdom$98Mlast round Nov 2026
  40. 40ProximaProxima provides strategic principal investments, governance advisory, and structured alternative solutions.

    Proxima provides strategic principal investments, governance advisory, and structured alternative solutions.

    Founded 2021United States$94Mlast round Jan 2026
  41. 41Nested TherapeuticsNested Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.

    Nested Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.

    Founded 2021Cambridge, United States$90Mlast round Oct 2022
  42. 42Life BiosciencesIntegrated preclinical CRO services provider

    Integrated preclinical CRO services provider

    Founded 2021United States$80Mlast round Apr 2026
  43. 43Atavistik BioAtavistik Bio is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.

    Atavistik Bio is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.

    Founded 2021Cambridge, United States$80Mlast round Mar 2026
  44. 44Lindus HealthLindus Health is a next-gen CRO running clinical trials for the health and biotech sectors.

    Lindus Health is a next-gen CRO running clinical trials for the health and biotech sectors.

    Founded 2021Boston, United Kingdom$77Mlast round Jan 2025
  45. 45Photys TherapeuticsPhotys Therapeutics is a biotechnology and pharmaceutical research company founded in 2021 and based in Waltham, Massachusetts.

    Photys Therapeutics is a biotechnology and pharmaceutical research company founded in 2021 and based in Waltham, Massachusetts.

    Founded 2021Waltham, United States$75Mlast round Sept 2022
  46. 46Ablaze PharmaceuticalsAblaze Pharmaceuticals is a clinical-stage biopharmaceutical company based in Shanghai, China, with an office in San Diego, California.

    Ablaze Pharmaceuticals is a clinical-stage biopharmaceutical company based in Shanghai, China, with an office in San Diego, California.

    Founded 2021China$75Mlast round Nov 2021
  47. 47Constructive BioConstructive Bio is a biotechnology company based in Cambridge, UK, founded in 2021 as a spin-out from Professor Jason Chin’s laboratory.

    Constructive Bio is a biotechnology company based in Cambridge, UK, founded in 2021 as a spin-out from Professor Jason Chin’s laboratory.

    Founded 2021Whittlesford, United Kingdom$73Mlast round Apr 2025
  48. 48CradleCradle Bio B.V.

    Cradle Bio B.V.

    Founded 2021Amsterdam, Netherlands$73Mlast round Nov 2024
  49. 49PandMePandMe is a DNA testing technology company that enables its users to access their ancestry, genealogy, and inherited traits.

    PandMe is a DNA testing technology company that enables its users to access their ancestry, genealogy, and inherited traits.

    Founded 2021London, United Kingdom$73Mlast round May 2021
  50. 50Congruence TherapeuticsCongruence Therapeutics is a Montreal-based biotechnology company founded in 2021 by Clarissa Desjardins, PhD, and Michael Rock Goldsmith.

    Congruence Therapeutics is a Montreal-based biotechnology company founded in 2021 by Clarissa Desjardins, PhD, and Michael Rock Goldsmith.

    Founded 2021Montreal, Canada$72Mlast round Mar 2026
Total fundinghow the list is ranked
15 November 2026updated nightly
Rounds we tracksource: Millionrounds

Companies founded in 2021 whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

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