Top list · Philadelphia
Biotech startups in Philadelphia
46 biotech startups in Philadelphia have raised money in rounds we track. These are the 46 that have raised the most, $2.0B between them.
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Century TherapeuticsCentury Therapeutics is a biotechnology company that develops cell therapies for hematological and solid tumor malignancies.Century Therapeutics is a biotechnology company that develops cell therapies for hematological and solid tumor malignancies.
Founded 2018Philadelphia, United States$385Mlast round Jan 2026 - 2
Dispatch BioDispatch Bio is a biotechnology company founded in 2022, focused on developing a universal treatment for solid tumors.Dispatch Bio is a biotechnology company founded in 2022, focused on developing a universal treatment for solid tumors.
Founded 2022Philadelphia, United States$216Mlast round Jul 2025 - 3
Alveus Therapeutics Inc.Alveus Therapeutics Inc is a clinical-stage biotechnology company focused on developing innovative therapies for obesity and metabolic diseases.Alveus Therapeutics Inc is a clinical-stage biotechnology company focused on developing innovative therapies for obesity and metabolic diseases.
Founded 2023Philadelphia, United States$197Mlast round Feb 2026 - 4
Latus BioLatus Bio is a biotechnology company based in Philadelphia, Pennsylvania, with an additional office in Boston.Latus Bio is a biotechnology company based in Philadelphia, Pennsylvania, with an additional office in Boston.
Founded 2022Philadelphia, United States$140Mlast round May 2026 - 5
Tarsa TherapeuticsTarsa Therapeutics develops an oral formulation of calcitonin for the treatment and prevention of postmenopausal osteoporosis.Tarsa Therapeutics develops an oral formulation of calcitonin for the treatment and prevention of postmenopausal osteoporosis.
Founded 2009Philadelphia, United States$121Mlast round Aug 2014 - 6
FORE BiotherapeuticsFore Biotherapeutics is a clinical-stage precision oncology company based in Philadelphia, PA.Fore Biotherapeutics is a clinical-stage precision oncology company based in Philadelphia, PA.
Founded 2011Philadelphia, United States$108Mlast round Jul 2026 - 7
Context TherapeuticsContext Therapeutics is a clinical-stage biopharmaceutical company.Context Therapeutics is a clinical-stage biopharmaceutical company.
Founded 2021Philadelphia, United States$100Mlast round May 2024 - 8
Carisma TherapeuticsCarisma Therapeutics is a biotech company that develops novel chimeric antigen receptor macrophage technology to treat solid tumors.Carisma Therapeutics is a biotech company that develops novel chimeric antigen receptor macrophage technology to treat solid tumors.
Founded 2016Philadelphia, United States$90Mlast round Sept 2022 - 9Limelight BioLimelight is building an industry-leading platform to develop technologies, advanced targets, and leading drug candidates.
Limelight is building an industry-leading platform to develop technologies, advanced targets, and leading drug candidates.
Founded 2016Philadelphia, United States$75Mlast round Dec 2019 - 10
ProsciaProscia is a Philadelphia-based software company founded in 2014 that focuses on transforming pathology from traditional methods to a digital, AI-driven approach.Proscia is a Philadelphia-based software company founded in 2014 that focuses on transforming pathology from traditional methods to a digital, AI-driven approach.
Founded 2016Philadelphia, United States$59Mlast round Mar 2025 - 11
Scout BioScout Bi is a biotechnology company that specializes in veterinary, animal health, and gene therapy.Scout Bi is a biotechnology company that specializes in veterinary, animal health, and gene therapy.
Founded 2016Philadelphia, United States$53Mlast round Oct 2021 - 12
Third Arc BioThird Arc Bio is a clinical-stage biotechnology company based in Philadelphia, Pennsylvania, founded in 2022.Third Arc Bio is a clinical-stage biotechnology company based in Philadelphia, Pennsylvania, founded in 2022.
Founded -Philadelphia, United States$52Mlast round Feb 2026 - 13
Aro BiotherapeuticsAro Biotherapeutics is a clinical-stage biotechnology company based in Philadelphia, Pennsylvania.Aro Biotherapeutics is a clinical-stage biotechnology company based in Philadelphia, Pennsylvania.
Founded 2018Philadelphia, United States$42Mlast round Nov 2023 - 14
RenovacorNo mercado desde 2009, a Renovacor Tintas se diferencia pela fabricação de tintas e revestimentos acrílicos de qualidade que conta com laboratório equipado, e tNo mercado desde 2009, a Renovacor Tintas se diferencia pela fabricação de tintas e revestimentos acrílicos de qualidade que conta com laboratório equipado, e t
Founded 2009Philadelphia, United States$41Mlast round Sept 2021 - 15
HealthVerityHealthVerity is a healthcare data technology company based in Philadelphia, founded in 2014.HealthVerity is a healthcare data technology company based in Philadelphia, founded in 2014.
Founded 2015Philadelphia, United States$35Mlast round Apr 2019 - 16
EnterinPhiladelphia-based biotechnology company .Philadelphia-based biotechnology company .
Founded 2016Philadelphia, United States$35Mlast round Dec 2023 - 17
GEMMABioGEMMABio is a therapeutics company that develops gene therapies for individuals living with rare diseases.GEMMABio is a therapeutics company that develops gene therapies for individuals living with rare diseases.
Founded -Philadelphia, United States$34Mlast round Dec 2024 - 18
Verismo TherapeuticsVerismo Therapeutics develops novel chimeric antigen receptors (CARs) that enhance T-cell-based cellular immunotherapy for cancer.Verismo Therapeutics develops novel chimeric antigen receptors (CARs) that enhance T-cell-based cellular immunotherapy for cancer.
Founded 2020Philadelphia, United States$28Mlast round May 2026 - 19ACT BiotechACT Biotech is a biopharmaceutical company focused on the development and commercialization of cancer drugs.
ACT Biotech is a biopharmaceutical company focused on the development and commercialization of cancer drugs.
Founded 2008Philadelphia, United States$26Mlast round May 2010 - 20
Vittoria Biotherapeutics, Inc.Vittoria Biotherapeutics, Inc.Vittoria Biotherapeutics, Inc.
Founded 2021Philadelphia, United States$25Mlast round Nov 2024 - 21
Tolerance BioTolerance Bio is a biotechnology company founded in 2023 and based in Philadelphia, Pennsylvania, with operations in Chapel Hill, North Carolina.Tolerance Bio is a biotechnology company founded in 2023 and based in Philadelphia, Pennsylvania, with operations in Chapel Hill, North Carolina.
Founded 2023Philadelphia, United States$20Mlast round Jun 2026 - 22
Avammune TherapeuticsAvammune Therapeutics is a Philadelphia-based biopharmaceutical company founded in 2019.Avammune Therapeutics is a Philadelphia-based biopharmaceutical company founded in 2019.
Founded 2019Philadelphia, United States$12Mlast round May 2025 - 23
NeuroFlowNeuroFlow is a healthcare technology and analytics company based in Philadelphia, established in 2016 or 2017.NeuroFlow is a healthcare technology and analytics company based in Philadelphia, established in 2016 or 2017.
Founded 2017Philadelphia, United States$10Mlast round May 2025 - 24
Verix HealthVerix Health is a healthcare technology company based in Santa Clara, California, focused on developing steerable surgical devices for minimally invasive cancerVerix Health is a healthcare technology company based in Santa Clara, California, focused on developing steerable surgical devices for minimally invasive cancer
Founded 2016Philadelphia, United States$8.0Mlast round Oct 2019 - 25
Vascular MagneticsVascular Magnetics develops vascular magnetic intervention (VMI), a therapy for peripheral artery disease.Vascular Magnetics develops vascular magnetic intervention (VMI), a therapy for peripheral artery disease.
Founded 2010Philadelphia, United States$7.0Mlast round Feb 2012 - 26
Excision BioTherapeuticsExcision is developing CRISPR-based therapies to cure viral infectious diseases and improve the lives of chronically ill patients.Excision is developing CRISPR-based therapies to cure viral infectious diseases and improve the lives of chronically ill patients.
Founded 2015Philadelphia, United States$6.8Mlast round Sept 2022 - 27
Cantai TherapeuticsCantai Therapeutics is a biotechnology company dedicated to developing bispecific antibodies aimed at treating autoimmune and inflammatory diseases.Cantai Therapeutics is a biotechnology company dedicated to developing bispecific antibodies aimed at treating autoimmune and inflammatory diseases.
Founded 2023Philadelphia, United States$6.5Mlast round Jan 2026 - 28
ClarioClario delivers the endpoint technology solutions for clinical trials.Clario delivers the endpoint technology solutions for clinical trials.
Founded 1972Philadelphia, United States$6.0Mlast round Jun 2026 - 29
RoundTripRoundTrip provides on-demand and scheduled non-emergency medical transportation for patients.RoundTrip provides on-demand and scheduled non-emergency medical transportation for patients.
Founded 2016Philadelphia, United States$5.1Mlast round Oct 2025 - 30
BlueWhale BioBlueWhale Bio, Inc.BlueWhale Bio, Inc.
Founded 1988Philadelphia, United States$5.0Mlast round Oct 2025 - 31
Mebias DiscoveryMebias Discovery holds a game-changing platform to discover next generation.Mebias Discovery holds a game-changing platform to discover next generation.
Founded 2015Philadelphia, United States$4.1Mlast round Sept 2022 - 32
Panorama MedicinePanorama Medicine is a genomics and AI-powered drug discovery startup based in Philadelphia, PA, founded in 2018.Panorama Medicine is a genomics and AI-powered drug discovery startup based in Philadelphia, PA, founded in 2018.
Founded 2018Philadelphia, United States$3.7Mlast round Apr 2019 - 33
BlackfynnBlackfynn is a Philadelphia-based life sciences company founded in 2015.Blackfynn is a Philadelphia-based life sciences company founded in 2015.
Founded 2015Philadelphia, United States$2.3Mlast round Nov 2017 - 34
Strados LabsStrados Labs innovates respiratory monitoring using smart biosensors and artificial intelligence.Strados Labs innovates respiratory monitoring using smart biosensors and artificial intelligence.
Founded 2016Philadelphia, United States$1.8Mlast round Jan 2026 - 35
ProlocorProlocor is a biotechnology and healthcare startup based in Philadelphia, Pennsylvania, founded in 2020.Prolocor is a biotechnology and healthcare startup based in Philadelphia, Pennsylvania, founded in 2020.
Founded 2020Philadelphia, United States$1.7Mlast round Feb 2024 - 36
BiomemeBiomeme is a real-time PCR thermocycler that attaches to iPhone 5s and enables DNA diagnostics and real-time disease surveillance.
Biomeme is a real-time PCR thermocycler that attaches to iPhone 5s and enables DNA diagnostics and real-time disease surveillance.
Founded 2012Philadelphia, United States$1.3Mlast round Jan 2014 - 37
Wistar InstituteThe Wistar Institute is the nation’s first independent institution devoted to medical research and training.The Wistar Institute is the nation’s first independent institution devoted to medical research and training.
Founded 1972Philadelphia, United States$1.1Mlast round Mar 2015 - 38
InstadiagnosticsInstadiagnostics Inc., is developing a rapid, quantitative, point-of-care (POC) diagnostic platform.Instadiagnostics Inc., is developing a rapid, quantitative, point-of-care (POC) diagnostic platform.
Founded 2015Philadelphia, United States$1.0Mlast round Aug 2021 - 39
Aqueduct FluidicsAqueduct Fluidics develops automation solutions for physical and life sciences research that fit on a laboratory benchtop.Aqueduct Fluidics develops automation solutions for physical and life sciences research that fit on a laboratory benchtop.
Founded 2019Philadelphia, United States$1.0Mlast round Dec 2021 - 40
Longevity BiotechLongevity Biotech develops a new class of therapeutics via artificial protein technology that focuses on pharmaceutical preparation.Longevity Biotech develops a new class of therapeutics via artificial protein technology that focuses on pharmaceutical preparation.
Founded 2010Philadelphia, United States$836Klast round Nov 2017 - 41
Opertech BioOpertech Bio is a Philadelphia-based company founded in 2011 that specializes in taste measurement technology for the food, beverage, pharmaceutical, and pet foOpertech Bio is a Philadelphia-based company founded in 2011 that specializes in taste measurement technology for the food, beverage, pharmaceutical, and pet fo
Founded 2011Philadelphia, United States$750Klast round Dec 2014 - 42
HueDxHueDx is a health technology company based in Philadelphia, specializing in the rapid development and launch of diagnostic tests.HueDx is a health technology company based in Philadelphia, specializing in the rapid development and launch of diagnostic tests.
Founded 2017Philadelphia, United States$655Klast round Jul 2020 - 43
BioLatticeBioLattice addresses the need for tissue healing solutions.BioLattice addresses the need for tissue healing solutions.
Founded -Philadelphia, United States$575Klast round Mar 2026 - 44
AUM LifeTechAUM LifeTech is an American Biotechnology company focused on using next-generation RNA silencing technology to develop solutions in diverse life science verticaAUM LifeTech is an American Biotechnology company focused on using next-generation RNA silencing technology to develop solutions in diverse life science vertica
Founded 2013Philadelphia, United States$400Klast round Aug 2022 - 45
OstiioOstiio develops a novel approach to correct skeletal deformities and deficiencies.Ostiio develops a novel approach to correct skeletal deformities and deficiencies.
Founded 2017Philadelphia, United States$25Klast round Oct 2021 - 46
ChronoWakeChronoWake is developing a product that utilizes advanced signal analysis and processing in order to wake its users at an ideal time within preference metrics.ChronoWake is developing a product that utilizes advanced signal analysis and processing in order to wake its users at an ideal time within preference metrics.
Founded 2008Philadelphia, United States$10Klast round Mar 2009
Philadelphia, United StatesCompanies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
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