Top list · Philadelphia
Startups in Philadelphia
216 startups in Philadelphia have raised money in rounds we track. These are the 50 that have raised the most, $3.9B between them.
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Century TherapeuticsCentury Therapeutics is a biotechnology company that develops cell therapies for hematological and solid tumor malignancies.Century Therapeutics is a biotechnology company that develops cell therapies for hematological and solid tumor malignancies.
Founded 2018Philadelphia, United States$385Mlast round Jan 2026 - 2
goPuffGopuff, officially known as GoBrands, Inc., is an American instant commerce and consumer goods delivery company based in Philadelphia, Pennsylvania.Gopuff, officially known as GoBrands, Inc., is an American instant commerce and consumer goods delivery company based in Philadelphia, Pennsylvania.
Founded 2013Philadelphia, United States$262Mlast round Nov 2025 - 3
dbt LabsDbt Labs develops an analytics engineering tool that prepares raw data in the warehouse for analysis.Dbt Labs develops an analytics engineering tool that prepares raw data in the warehouse for analysis.
Founded 2016Philadelphia, United States$222Mlast round Feb 2022 - 4
Dispatch BioDispatch Bio is a biotechnology company founded in 2022, focused on developing a universal treatment for solid tumors.Dispatch Bio is a biotechnology company founded in 2022, focused on developing a universal treatment for solid tumors.
Founded 2022Philadelphia, United States$216Mlast round Jul 2025 - 5
Alveus Therapeutics Inc.Alveus Therapeutics Inc is a clinical-stage biotechnology company focused on developing innovative therapies for obesity and metabolic diseases.Alveus Therapeutics Inc is a clinical-stage biotechnology company focused on developing innovative therapies for obesity and metabolic diseases.
Founded 2023Philadelphia, United States$197Mlast round Feb 2026 - 6
Latus BioLatus Bio is a biotechnology company based in Philadelphia, Pennsylvania, with an additional office in Boston.Latus Bio is a biotechnology company based in Philadelphia, Pennsylvania, with an additional office in Boston.
Founded 2022Philadelphia, United States$140Mlast round May 2026 - 7
InstaMedInstaMed simplifies healthcare payments for providers.InstaMed simplifies healthcare payments for providers.
Founded 2004Philadelphia, United States$127Mlast round Sept 2016 - 8
LEAF Commercial CapitalLEAF Commercial Capital engages in equipment lease, note origination servicing and financing activities.LEAF Commercial Capital engages in equipment lease, note origination servicing and financing activities.
Founded 2010Philadelphia, United States$125Mlast round Nov 2011 - 9
Tarsa TherapeuticsTarsa Therapeutics develops an oral formulation of calcitonin for the treatment and prevention of postmenopausal osteoporosis.Tarsa Therapeutics develops an oral formulation of calcitonin for the treatment and prevention of postmenopausal osteoporosis.
Founded 2009Philadelphia, United States$121Mlast round Aug 2014 - 10
FORE BiotherapeuticsFore Biotherapeutics is a clinical-stage precision oncology company based in Philadelphia, PA.Fore Biotherapeutics is a clinical-stage precision oncology company based in Philadelphia, PA.
Founded 2011Philadelphia, United States$108Mlast round Jul 2026 - 11
HouwzerHouwzer is a modern real estate and mortgage brokerage based in Philadelphia, Pennsylvania, founded in 2014.Houwzer is a modern real estate and mortgage brokerage based in Philadelphia, Pennsylvania, founded in 2014.
Founded 2015Philadelphia, United States$107Mlast round Feb 2022 - 12
Context TherapeuticsContext Therapeutics is a clinical-stage biopharmaceutical company.Context Therapeutics is a clinical-stage biopharmaceutical company.
Founded 2021Philadelphia, United States$100Mlast round May 2024 - 13
ScopeSCOPE is a commercial real estate firm offering investment sales, debt consulting, and asset advisory services.SCOPE is a commercial real estate firm offering investment sales, debt consulting, and asset advisory services.
Founded 2019Philadelphia, United States$90Mlast round Jun 2024 - 14
Carisma TherapeuticsCarisma Therapeutics is a biotech company that develops novel chimeric antigen receptor macrophage technology to treat solid tumors.Carisma Therapeutics is a biotech company that develops novel chimeric antigen receptor macrophage technology to treat solid tumors.
Founded 2016Philadelphia, United States$90Mlast round Sept 2022 - 15
Datavault AIDatavault AI develops spatial audio wireless technology for smart devices and home entertainment systems.Datavault AI develops spatial audio wireless technology for smart devices and home entertainment systems.
Founded -Philadelphia, United States$89Mlast round Aug 2026 - 16
ChargeItSpotChargeItSpot specializes in providing free and secure cell phone charging stations.ChargeItSpot specializes in providing free and secure cell phone charging stations.
Founded 2011Philadelphia, United States$81Mlast round Aug 2026 - 17
CrossbeamCrossbeam is the first and largest Ecosystem-Led Growth platform.Crossbeam is the first and largest Ecosystem-Led Growth platform.
Founded 2018Philadelphia, United States$79Mlast round Oct 2021 - 18
Liberty SBFCommercial real estate lending companyCommercial real estate lending company
Founded 2011Philadelphia, United States$75Mlast round Jun 2016 - 19Limelight BioLimelight is building an industry-leading platform to develop technologies, advanced targets, and leading drug candidates.
Limelight is building an industry-leading platform to develop technologies, advanced targets, and leading drug candidates.
Founded 2016Philadelphia, United States$75Mlast round Dec 2019 - 20
Interius BioTherapeuticsInterius BioTherapeutics is a biopharmaceutical company that develops in vivo cell-specific gene medicines to treat B cell lymphomas.Interius BioTherapeutics is a biopharmaceutical company that develops in vivo cell-specific gene medicines to treat B cell lymphomas.
Founded 2019Philadelphia, United States$73Mlast round Jan 2025 - 21
GuruGuru is an Enterprise AI Search, Intranet, and Wiki platform allowing you to find and share information from anywhere to anywhere.Guru is an Enterprise AI Search, Intranet, and Wiki platform allowing you to find and share information from anywhere to anywhere.
Founded 2013Philadelphia, United States$71Mlast round Oct 2024 - 22
SidecarSidecar is an e-commerce marketing company that builds the technology retailers need to optimize cross-channel online shopping campaigns.Sidecar is an e-commerce marketing company that builds the technology retailers need to optimize cross-channel online shopping campaigns.
Founded 2007Philadelphia, United States$62Mlast round May 2017 - 23
ProsciaProscia is a Philadelphia-based software company founded in 2014 that focuses on transforming pathology from traditional methods to a digital, AI-driven approach.Proscia is a Philadelphia-based software company founded in 2014 that focuses on transforming pathology from traditional methods to a digital, AI-driven approach.
Founded 2016Philadelphia, United States$59Mlast round Mar 2025 - 24
Belong HealthBelong Health is a digital health company founded in 2021, focused on partnering with regional payers to enhance Medicare Advantage and Special Needs Plans (SNPs).Belong Health is a digital health company founded in 2021, focused on partnering with regional payers to enhance Medicare Advantage and Special Needs Plans (SNPs).
Founded 2021Philadelphia, United States$57Mlast round Jul 2025 - 25
Scout BioScout Bi is a biotechnology company that specializes in veterinary, animal health, and gene therapy.Scout Bi is a biotechnology company that specializes in veterinary, animal health, and gene therapy.
Founded 2016Philadelphia, United States$53Mlast round Oct 2021 - 26
Third Arc BioThird Arc Bio is a clinical-stage biotechnology company based in Philadelphia, Pennsylvania, founded in 2022.Third Arc Bio is a clinical-stage biotechnology company based in Philadelphia, Pennsylvania, founded in 2022.
Founded -Philadelphia, United States$52Mlast round Feb 2026 - 27
Vitara BiomedicalVitara Biomedical is a Philadelphia-based medical technology company founded in 2019, dedicated to improving care for extremely premature newborns.Vitara Biomedical is a Philadelphia-based medical technology company founded in 2019, dedicated to improving care for extremely premature newborns.
Founded 2019Philadelphia, United States$50Mlast round Nov 2024 - 28
Chubby GroupChubby Group is a US-based Food and Beverage holding company, founded in 2014 and headquartered in the United States.Chubby Group is a US-based Food and Beverage holding company, founded in 2014 and headquartered in the United States.
Founded 2014Philadelphia, United States$50Mlast round Oct 2026 - 29
FSH TechnologiesFSH Technologies is a Philadelphia-based government software company that focuses on creating user-friendly software for local governments, school districts, anFSH Technologies is a Philadelphia-based government software company that focuses on creating user-friendly software for local governments, school districts, an
Founded 2021Philadelphia, United States$45Mlast round Aug 2026 - 30
QuotaPathQuotaPath is a sales compensation and commission tracking software company founded in 2018, co-headquartered in Philadelphia, Pennsylvania, and Austin, Texas.QuotaPath is a sales compensation and commission tracking software company founded in 2018, co-headquartered in Philadelphia, Pennsylvania, and Austin, Texas.
Founded 2018Philadelphia, United States$45Mlast round Apr 2022 - 31
Aro BiotherapeuticsAro Biotherapeutics is a clinical-stage biotechnology company based in Philadelphia, Pennsylvania.Aro Biotherapeutics is a clinical-stage biotechnology company based in Philadelphia, Pennsylvania.
Founded 2018Philadelphia, United States$42Mlast round Nov 2023 - 32
RenovacorNo mercado desde 2009, a Renovacor Tintas se diferencia pela fabricação de tintas e revestimentos acrílicos de qualidade que conta com laboratório equipado, e tNo mercado desde 2009, a Renovacor Tintas se diferencia pela fabricação de tintas e revestimentos acrílicos de qualidade que conta com laboratório equipado, e t
Founded 2009Philadelphia, United States$41Mlast round Sept 2021 - 33
CuralateCuralate optimizes digital commerce for discovery.Curalate optimizes digital commerce for discovery.
Founded 2012Philadelphia, United States$40Mlast round Feb 2016 - 34
FORT RoboticsFORT Robotics is a safety and security platform designed to secure autonomous machines from cybersecurity attacks.FORT Robotics is a safety and security platform designed to secure autonomous machines from cybersecurity attacks.
Founded 2018Philadelphia, United States$39Mlast round Oct 2026 - 35
ConnectDERConnectDER is an energy technology company based in Philadelphia, founded in 2011.ConnectDER is an energy technology company based in Philadelphia, founded in 2011.
Founded 2011Philadelphia, United States$35Mlast round Dec 2024 - 36
RittenRitten is a Philadelphia-based behavioral health technology company founded in 2020.Ritten is a Philadelphia-based behavioral health technology company founded in 2020.
Founded 2020Philadelphia, United States$35Mlast round Dec 2025 - 37
HealthVerityHealthVerity is a healthcare data technology company based in Philadelphia, founded in 2014.HealthVerity is a healthcare data technology company based in Philadelphia, founded in 2014.
Founded 2015Philadelphia, United States$35Mlast round Apr 2019 - 38
BurroBurro is an agricultural technology company based in Philadelphia, founded in 2017.Burro is an agricultural technology company based in Philadelphia, founded in 2017.
Founded 2017Philadelphia, United States$35Mlast round Jan 2024 - 39
EnterinPhiladelphia-based biotechnology company .Philadelphia-based biotechnology company .
Founded 2016Philadelphia, United States$35Mlast round Dec 2023 - 40
GEMMABioGEMMABio is a therapeutics company that develops gene therapies for individuals living with rare diseases.GEMMABio is a therapeutics company that develops gene therapies for individuals living with rare diseases.
Founded -Philadelphia, United States$34Mlast round Dec 2024 - 41
Credit GenieCredit Genie is a U.S.-based FinTech company founded in 2019 by Ed Harycki, who previously founded Swift Capital.Credit Genie is a U.S.-based FinTech company founded in 2019 by Ed Harycki, who previously founded Swift Capital.
Founded 2019Philadelphia, United States$34Mlast round Feb 2025 - 42
CoJourneyCoJourney is a global Contract Development and Manufacturing Organization (CDMO) focused on cell and gene therapy.CoJourney is a global Contract Development and Manufacturing Organization (CDMO) focused on cell and gene therapy.
Founded 2021Philadelphia, United States$30Mlast round Jun 2023 - 43
Verismo TherapeuticsVerismo Therapeutics develops novel chimeric antigen receptors (CARs) that enhance T-cell-based cellular immunotherapy for cancer.Verismo Therapeutics develops novel chimeric antigen receptors (CARs) that enhance T-cell-based cellular immunotherapy for cancer.
Founded 2020Philadelphia, United States$28Mlast round May 2026 - 44ACT BiotechACT Biotech is a biopharmaceutical company focused on the development and commercialization of cancer drugs.
ACT Biotech is a biopharmaceutical company focused on the development and commercialization of cancer drugs.
Founded 2008Philadelphia, United States$26Mlast round May 2010 - 45
honeygrowHoneygrow is a fast-casual restaurant chain founded in 2012 by Justin Rosenberg in Philadelphia.Honeygrow is a fast-casual restaurant chain founded in 2012 by Justin Rosenberg in Philadelphia.
Founded 2012Philadelphia, United States$25Mlast round Jun 2015 - 46
Vittoria Biotherapeutics, Inc.Vittoria Biotherapeutics, Inc.Vittoria Biotherapeutics, Inc.
Founded 2021Philadelphia, United States$25Mlast round Nov 2024 - 47
MedAvanteMedAvante is the leading global provider of technology-enabled signal detection solutions in clinical trials of treatments.MedAvante is the leading global provider of technology-enabled signal detection solutions in clinical trials of treatments.
Founded 2002Philadelphia, United States$22Mlast round Jul 2015 - 48
Exyn TechnologiesExyn Technologies is a developer of autonomous aerial robot systems.Exyn Technologies is a developer of autonomous aerial robot systems.
Founded 2014Philadelphia, United States$21Mlast round Jul 2024 - 49
Tolerance BioTolerance Bio is a biotechnology company founded in 2023 and based in Philadelphia, Pennsylvania, with operations in Chapel Hill, North Carolina.Tolerance Bio is a biotechnology company founded in 2023 and based in Philadelphia, Pennsylvania, with operations in Chapel Hill, North Carolina.
Founded 2023Philadelphia, United States$20Mlast round Jun 2026 - 50
Daymark HealthDaymark Health is a Philadelphia-based cancer care company founded in 2022, with its public launch in April 2025.Daymark Health is a Philadelphia-based cancer care company founded in 2022, with its public launch in April 2025.
Founded 2024Philadelphia, United States$20Mlast round Sept 2025
Philadelphia, United StatesEvery startup we hold in Philadelphia, ranked by the total it has raised in rounds we hold. Nobody pays to be on a list.
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