Top list · Cambridge
Biotech startups in Cambridge
183 biotech startups in Cambridge have raised money in rounds we track. These are the 50 that have raised the most, $16B between them.
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Blueprint MedicinesBlueprint Medicines is a global, fully integrated biopharmaceutical company that invents life-changing medicines.Blueprint Medicines is a global, fully integrated biopharmaceutical company that invents life-changing medicines.
Founded 2011Cambridge, United States$1.4Blast round Jun 2022 - 2
EQRxEQRx is a biotechnology company that focuses on re-engineering the process of drug discovery to make them affordable.EQRx is a biotechnology company that focuses on re-engineering the process of drug discovery to make them affordable.
Founded 2019Cambridge, United States$1.2Blast round Dec 2021 - 3
Relay TherapeuticsRelay therapeutics is a developer of an allosteric drug-discovery platform intended to apply computational techniques to protein motion.Relay therapeutics is a developer of an allosteric drug-discovery platform intended to apply computational techniques to protein motion.
Founded 2016Cambridge, United States$932Mlast round May 2026 - 4
Tango TherapeuticsTango Therapeutics is a biotechnology company that is developing next generation cancer therapies.Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.
Founded 2017Cambridge, United States$852Mlast round Jun 2026 - 5
Kymera TherapeuticsKymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.
Founded 2017Cambridge, United States$799Mlast round Dec 2025 - 6
ModernaLearn how we’re changing the world of medicine.Learn how we’re changing the world of medicine.
Founded 2013Cambridge, United States$675Mlast round Jun 2026 - 7
Flagship PioneeringPioneering Medicines is a biotechnology research agency providing biotechnology to life sciences services.Pioneering Medicines is a biotechnology research agency providing biotechnology to life sciences services.
Founded 2000Cambridge, United States$618Mlast round Dec 2017 - 8
Lila SciencesLila Sciences is a biotechnology company based in Cambridge, Massachusetts, founded in 2023 through a merger of two projects from Flagship Pioneering.Lila Sciences is a biotechnology company based in Cambridge, Massachusetts, founded in 2023 through a merger of two projects from Flagship Pioneering.
Founded -Cambridge, United States$551Mlast round Jan 2026 - 9
Akero TherapeuticsAkero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state.Akero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state.
Founded 2017Cambridge, United States$502Mlast round Mar 2024 - 10
NuvalentNuvalent is a biopharmaceutical company that develops targeted therapies for cancer by designing small-molecule medicines.Nuvalent is a biopharmaceutical company that develops targeted therapies for cancer by designing small-molecule medicines.
Founded 2017Cambridge, United States$500Mlast round Nov 2025 - 11
Intellia TherapeuticsIntellia Therapeutics is a genome editing company that develops curative gene-editing treatments.Intellia Therapeutics is a genome editing company that develops curative gene-editing treatments.
Founded 2014Cambridge, United States$485Mlast round Sept 2026 - 12
LarondeLaronde develops an eRNA-based therapeutic platform that is capable of indicating diverse proteins inside the body.Laronde develops an eRNA-based therapeutic platform that is capable of indicating diverse proteins inside the body.
Founded 2017Cambridge, United States$440Mlast round Aug 2021 - 13
Editas MedicineEditas Medicine is a clinical-stage genome editing company that develops genomic medicines for serious diseases.Editas Medicine is a clinical-stage genome editing company that develops genomic medicines for serious diseases.
Founded 2013Cambridge, United States$335Mlast round May 2026 - 14
Beam TherapeuticsBeam Therapeutics is a biotechnology company developing precision genetic medicines through the use of base editing technology.Beam Therapeutics is a biotechnology company developing precision genetic medicines through the use of base editing technology.
Founded 2017Cambridge, United States$322Mlast round Feb 2026 - 15
Fulcrum TherapeuticsFulcrum Therapeutics is a biotechnology company that focuses on identifying and treating rare genetic diseases at their root cause.Fulcrum Therapeutics is a biotechnology company that focuses on identifying and treating rare genetic diseases at their root cause.
Founded 2016Cambridge, United States$310Mlast round Dec 2025 - 16
Rubius TherapeuticsRubius has developed the technology to grow, genetically engineer and mature long-circulating Red-Cell Therapeutics.Rubius has developed the technology to grow, genetically engineer and mature long-circulating Red-Cell Therapeutics.
Founded 2013Cambridge, United States$300Mlast round Mar 2021 - 17
ReNAgade TherapeuticsReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease.ReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease.
Founded 2021Cambridge, United States$300Mlast round May 2023 - 18
Strand TherapeuticsStrand Therapeutics is a biopharmaceutical company applying synthetic biology to RNA therapeutics to develop single dose mRNA treatments.Strand Therapeutics is a biopharmaceutical company applying synthetic biology to RNA therapeutics to develop single dose mRNA treatments.
Founded 2017Cambridge, United States$267Mlast round Mar 2026 - 19
Centessa PharmaceuticalsCentessa Pharmaceuticals is a pharmaceutical company that focuses on drug development to address significant medical needs.Centessa Pharmaceuticals is a pharmaceutical company that focuses on drug development to address significant medical needs.
Founded 2021Cambridge, United States$250Mlast round Nov 2025 - 20
TriNetXTriNetX is a health research network that connects drug discovery and development from pharmaceutical companies.TriNetX is a health research network that connects drug discovery and development from pharmaceutical companies.
Founded 2013Cambridge, United States$240Mlast round Apr 2026 - 21
LifeMine TherapeuticsLifeMine Therapeutics combines genomics with AI and synthetic biology to discover and develop a pipeline of novel medicines.LifeMine Therapeutics combines genomics with AI and synthetic biology to discover and develop a pipeline of novel medicines.
Founded 2016Cambridge, United States$230Mlast round Mar 2022 - 22
Orna TherapeuticsOrna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA therapeutics to treat various diseases.Orna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA therapeutics to treat various diseases.
Founded 2019Cambridge, United States$221Mlast round Aug 2022 - 23
Matchpoint TherapeuticsMatchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.Matchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.
Founded 2021Cambridge, United States$220Mlast round Oct 2026 - 24
Obsidian TherapeuticsObsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.
Founded 2015Cambridge, United States$210Mlast round Apr 2024 - 25
Aviceda TherapeuticsAviceda Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2018.Aviceda Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2018.
Founded 2018Cambridge, United States$208Mlast round Jan 2025 - 26
Voyager TherapeuticsVoyager Therapeutics is a biotechnology company specializing in gene therapy and neurology.Voyager Therapeutics is a biotechnology company specializing in gene therapy and neurology.
Founded 2013Cambridge, United States$205Mlast round Jan 2024 - 27
Q32 BioQ32 Bio is a biotechnology company that develops treatments for patients with severe autoimmune and inflammatory diseases.Q32 Bio is a biotechnology company that develops treatments for patients with severe autoimmune and inflammatory diseases.
Founded -Cambridge, United States$200Mlast round Jul 2026 - 28
Spero TherapeuticsSpero Therapeutics develops therapeutics for treatment of gram-negative infections.Spero Therapeutics develops therapeutics for treatment of gram-negative infections.
Founded 2013Cambridge, United States$199Mlast round Jul 2026 - 29
CREATE MedicinesCREATE Medicines is a clinical-stage biotechnology company based in Cambridge, Massachusetts.CREATE Medicines is a clinical-stage biotechnology company based in Cambridge, Massachusetts.
Founded 2019Cambridge, United States$195Mlast round May 2026 - 30
X4 PharmaceuticalsX4 Pharmaceuticals is a clinical-stage oncology company developing oral small molecule CXCR4 antagonists for the treatment.X4 Pharmaceuticals is a clinical-stage oncology company developing oral small molecule CXCR4 antagonists for the treatment.
Founded 2012Cambridge, United States$193Mlast round Oct 2025 - 31
Generation BioGeneration Bio is a biotechnology company that develops genetic medicines to treat genetic disorders.Generation Bio is a biotechnology company that develops genetic medicines to treat genetic disorders.
Founded 2016Cambridge, United States$176Mlast round Mar 2023 - 32
Amylyx PharmaceuticalsAmylyx Pharmaceuticals specializes in providing solutions for Alzheimer’s and other diseases of the brain.Amylyx Pharmaceuticals specializes in providing solutions for Alzheimer’s and other diseases of the brain.
Founded 2014Cambridge, United States$175Mlast round Sept 2025 - 33
Scholar RockScholar Rock is a biopharmaceutical company that develops and discovers new medicines and treatments for the serious diseases.Scholar Rock is a biopharmaceutical company that develops and discovers new medicines and treatments for the serious diseases.
Founded 2012Cambridge, United States$167Mlast round Mar 2026 - 34
Ethyreal BioEthyreal Bio is a biotechnology startup developing precision therapies for autoimmune thyroid disorders.Ethyreal Bio is a biotechnology startup developing precision therapies for autoimmune thyroid disorders.
Founded -Cambridge, United States$161Mlast round Jun 2026 - 35
Black Diamond TherapeuticsBlack Diamond Therapeutics is a medical company focused on analyzing genetically defined cancers.Black Diamond Therapeutics is a medical company focused on analyzing genetically defined cancers.
Founded 2016Cambridge, United States$160Mlast round Jun 2023 - 36
GentiBioGentiBio is a clinical-stage biotherapeutics company founded in 2020, focused on developing engineered regulatory T-cell therapies (EngTregs) to address Type 1 GentiBio is a clinical-stage biotherapeutics company founded in 2020, focused on developing engineered regulatory T-cell therapies (EngTregs) to address Type 1
Founded 2020Cambridge, United States$157Mlast round Aug 2021 - 37
AIRNAAIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.AIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.
Founded 2021Cambridge, United States$155Mlast round Apr 2025 - 38
Alkeus PharmaceuticalsAlkeus Pharmaceuticals is a Boston-based startup focused on treatments for serious ophthalmic conditions.Alkeus Pharmaceuticals is a Boston-based startup focused on treatments for serious ophthalmic conditions.
Founded 2011Cambridge, United States$150Mlast round Jun 2023 - 39
MOMA TherapeuticsMOMA Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2020.MOMA Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2020.
Founded 2020Cambridge, United States$150Mlast round May 2022 - 40
Mersana TherapeuticsMersana Therapeutics develops a biodegradable polymer platform Fleximer® which creates new and better medicines.Mersana Therapeutics develops a biodegradable polymer platform Fleximer® which creates new and better medicines.
Founded 2005Cambridge, United States$148Mlast round Jun 2016 - 41
Vedanta BiosciencesVedanta Biosciences creates microbiome-derived therapies to address immune and infectious diseases by modulating the gut microbiota.Vedanta Biosciences creates microbiome-derived therapies to address immune and infectious diseases by modulating the gut microbiota.
Founded 2010Cambridge, United States$143Mlast round Apr 2024 - 42
BIND TherapeuticsBIND Therapeutics is a biotechnology company incorporated in 2006; Pfizer acquired substantially all of its assets in 2016.BIND Therapeutics is a biotechnology company incorporated in 2006; Pfizer acquired substantially all of its assets in 2016.
Founded 2006Cambridge, United States$138Mlast round Sept 2013 - 43
Broad InstituteThe Broad Institute brings together a diverse group of individuals from across its partner institutions to confront biomedical challenges.
The Broad Institute brings together a diverse group of individuals from across its partner institutions to confront biomedical challenges.
Founded 2003Cambridge, United States$133Mlast round Nov 2013 - 44
ARTBIOARTBIO is a clinical-stage biotechnology company founded in 2021, focused on developing alpha radioligand therapies for targeted cancer treatment.ARTBIO is a clinical-stage biotechnology company founded in 2021, focused on developing alpha radioligand therapies for targeted cancer treatment.
Founded 2021Cambridge, United States$132Mlast round Jul 2025 - 45
Vigil NeuroscienceVigil Neuroscience is a biotechnology company that develops novel therapeutics for neurodegenerative diseases.Vigil Neuroscience is a biotechnology company that develops novel therapeutics for neurodegenerative diseases.
Founded 2020Cambridge, United States$130Mlast round Jun 2024 - 46
Acrivon TherapeuticsAcrivon Therapeutics is a precision oncology therapeutics company specializing in drug development through early clinical treatment success.Acrivon Therapeutics is a precision oncology therapeutics company specializing in drug development through early clinical treatment success.
Founded 2018Cambridge, United States$130Mlast round Apr 2024 - 47
C4 TherapeuticsC4 Therapeutics develops novel early stage therapies that eliminate disease-causing proteins.C4 Therapeutics develops novel early stage therapies that eliminate disease-causing proteins.
Founded 2015Cambridge, United States$125Mlast round Oct 2025 - 482seventy bio2seventy bio is an immuno-oncology cell therapy company that discovers and develops cancer therapies.
2seventy bio is an immuno-oncology cell therapy company that discovers and develops cancer therapies.
Founded 2021Cambridge, United States$125Mlast round Feb 2023 - 49
Senda BiosciencesSenda Biosciences is a therapeutics platform company leveraging unprecedented insights into the molecular connections between humans.Senda Biosciences is a therapeutics platform company leveraging unprecedented insights into the molecular connections between humans.
Founded 2017Cambridge, United States$123Mlast round Aug 2022 - 50
Merida BiosciencesMerida Biosciences is a biotechnology company based in Cambridge, Massachusetts, focused on developing precision medicines for autoimmune and allergic diseases.Merida Biosciences is a biotechnology company based in Cambridge, Massachusetts, focused on developing precision medicines for autoimmune and allergic diseases.
Founded 2022Cambridge, United States$121Mlast round Apr 2025
Cambridge, United StatesCompanies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
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