Puzzle Medical Devices Inc.

Puzzle Medical Devices® Inc.

is a Montreal-based medtech startup founded in 2018. The company focuses on developing a minimally invasive, percutaneous heart pump designed to support cardiac and renal function in patients with advanced heart failure. Its primary product, the ModulHeartTM, features a modular design with multiple endovascular pumps that provide hemodynamic support while preserving blood integrity and reducing the risk of embolic events. The company is dedicated to improving patient outcomes and has made significant progress in its development activities. It has completed several acute preclinical studies and is advancing clinical trials to evaluate the safety and efficacy of the ModulHeartTM. Puzzle Medical Devices has also received FDA Breakthrough Device Designation, which helps accelerate the development of its technology for fragile patients. The company targets patients who are not candidates for heart transplant or surgical mechanical circulatory support, aiming to enhance their quality of life and reduce the economic burden of heart failure.