Engine Biosciences

Engine Biosciences is a biotechnology company founded in 2014, focused on precision medicine through the integration of machine learning, functional genomics, and drug discovery.

Headquartered in Singapore, with a presence in Silicon Valley, the company aims to develop impactful therapeutics, particularly in oncology, by centering its efforts around patient-specific genetic and treatment contexts. The company operates a proprietary platform called NetMAPPR, which combines rapid wet-lab experimentation with artificial intelligence. Key technologies include the CombiGEM system for high-throughput screening, proprietary CRISPR screens for genetic interactions, and advanced machine learning algorithms for mapping biological networks. Engine Biosciences serves the healthcare and pharmaceutical industries, partnering with biopharma companies and research institutions to accelerate drug discovery and develop new therapies and biomarkers. Notable collaborations include a partnership with Singapore’s Experimental Drug Development Centre to advance cancer therapies.