What does Spero Ventures invest in?
Spero Ventures invests most often at Series A and Seed (83% of the rounds on record), in sectors such as Tech-enabled Health, Digital-health and Wellbeing.

United States · Investor
Last cheque observed Jul 2025. Silence since then is not evidence of inactivity: our sources miss unannounced rounds.
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8 rounds on record
Mostly Series A and Seed: 83% of its rounds
Led 3 rounds
A boutique venture firm crafted from the ground up for purpose-led companiesFrom their own website
Every round we can evidence, newest first8 appearances
1 round
1 round
3 rounds
3 rounds
An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.
Named by the firm itself, on a filing, its Form ADV or its company registration2 named
We also hold 8 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.
From the firm's own filings with the SEC, which it must file accurately by law
From their own portfolio page (on their website)
Allie-aiAralezbioBaseoperationsCanopyworksConfirmCorvus-roboticsEliEuclidpowerGencoveHyroMastreforestMobiusmaterialsOovaPickaxeSorafuelTelotrucksTinyhealthClarityGuideHuckleberrycareJunokidsMarctarpenningPersist-aiSingularityTalkshopVistapathWattchWithleafWithremark
Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.
The latest companies Spero Ventures put money into.
1 episode naming Spero Ventures in the title, and 1 more that mention it.

Inside the mind of Shripriya Mahesh, Founding Partner, Spero Ventures
WithShripriya Mahesh
MentionsSpero VenturesOmidyar Network

Tesla Co-founder, Marc Tarpenning
Spero Ventures invests most often at Series A and Seed (83% of the rounds on record), in sectors such as Tech-enabled Health, Digital-health and Wellbeing.
8 investments on record, 0 of them in the last 12 months, and it led 3. The most recent was in Jul 2025.
Its most recent investments on record: Remark (Series A, Jul 2025), Leaf Agriculture (Series A, Aug 2024) and Indus.AI (Series A, Sept 2019).
The median round it joins is $11M. It says it writes cheques of $2.0M to $25M.
Yes: it led 3 of its 8 investments on record (38%).
Most of the companies it backs are in the United States (100%).
No investments in the last 12 months; the latest was in Jul 2025.
Spero Ventures is a VC firm based in Burlingame, United States.
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Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it