Australia · Investor

Main Sequence Ventures

Last cheque observed Sep 2026; 84 cheques on record.

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Deploying nowVC firm

Pre-seedSeedSeries ASpaceClimateTechnology

Deploying now
87%of best year26cheques in 12 months, 84 on record
Since the last cheque38days00hrs00min00sec
Median round$13MCheque size, as they say$250K – $20MRounds led9 of 84Sole investor14 roundsMostly inAustralia, 92%
Pitch Main Sequence Ventures

Main Sequence Ventures highlights

  1. 01

    26 cheques in the last 12 months

  2. 02

    Mostly Venture and Series A: 56% of its rounds

  3. 03

    Sole investor in 14 rounds, median $2.2M

What they do

a venture capital firm designed for deeptechFrom their own website
Type
VC firm (from a list, unverified)
Cheque size
$250K – $20M as they say
Stages
Pre-seedSeedSeries ASeries BGrowth
Sectors
SpaceClimateTechnology
Based in
Eveleigh, Australia
Cold pitches
Not stated

The record

Every round we can evidence, newest first84 appearances

  1. 2026

    21 rounds

  2. Sept
    Kinoxis TherapeuticsAU · Startup Daily$4.8MLed
  3. Sept
    Amber ElectricSeries E · AU · TechStartups$56MWith 9 others
  4. Sept
    Metacognition AIPre-seed · AU · TechStartups$10MLed
  5. Sept
    Universal QuantumSeries A · GB · Tech.eu$100MWith 18 others
  6. Aug
    Facet AmtechSeed · AU$2.2MWith 2 others
  7. Jul
    EmesentAU · Startup Daily$15MWith 6 others
  8. Jun
    Number 8 bioGrant · AU$15KWith 1 other
  9. May
    ArkeusSeries A · AU · Firms' own news pages$25MWith 6 others
  10. May
    DiraqGrant · AU$38MWith 2 others
  11. Apr
    AigentsphereSeed · AU · Startup Daily$4.0MLed
  12. Apr
    DeteqtSeed · AU · Startup Daily$5.0MLed
  13. Apr
    ULUUGrant · AU$1.5MWith 2 others
  14. Mar
    Advanced NavigationSeries C · AU · Startup Daily$158MWith 4 others
  15. Mar
    MGA ThermalVenture · AU · Startup Daily$12MWith 3 others
  16. Mar
    Number 8 bioGrant · AU$834KWith 2 others
  17. Mar
    Cauldron FermSeries A · AU$13MWith 3 others
  18. Feb
    BreakerSeed · AU · Startup Daily$9.0MWith 2 others
  19. Feb
    KasadaVentureburn$20MWith 6 others
  20. Feb
    DiraqVenture · AU$14MWith 1 other
  21. Jan
    Gilmour Space TechnologiesGrowth · AU · Startup Daily$217MWith 9 others
  22. Jan
    Gilmour Space TechnologiesSeries E · AU$146MWith 2 others
  23. 2025

    24 rounds

  24. Dec
    KasadaAU · Startup Daily$20MWith 6 others
  25. Dec
    ULUUGrant · AU$990KWith 2 others
  26. Nov
    Number 8 BioSeries A · AU · Startup Daily$11MWith 2 others
  27. Nov
    Sundrive SolarGrant · AU$17MWith 2 others
  28. Nov
    The EVERY CompanySeries D · US$55MWith 4 others
  29. Oct
    UluuSeries A · AU · Startup Daily$16MWith 5 others
  30. Oct
    RainStickVenture · CAUndisclosedWith 2 others
  31. Oct
    Cauldron FermVenture · AUUndisclosedWith 3 others
  32. Sept
    AndromedaSeries A · AU · Startup Daily$23MWith 8 others
  33. Sept
    Morse MicroSeries C · AU$58MWith 5 others
  34. Sept
    Andromeda RoboticsSeries A · AU$15MWith 3 others
  35. Sept
    EnduaGrant · AU$20KSole investor
  36. Jul
    DiraqAU · Startup Daily$15MWith 5 others
  37. Jul
    ArkeusGrant · AU$1.6MSole investor
  38. Jul
    v2foodVenture · AU$17MWith 3 others
  39. May
    LevurPre-seed · AU · Startup Daily$1.2MLed
  40. Apr
    QuintessenceLabsVenture · AU$13MWith 2 others
  41. Mar
    DeteQtPre-seed · AU · Startup Daily$750KWith 1 other
  42. Mar
    BreakerPre-seed · AU · Startup Daily$2.0MLed

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

The team

We hold 20 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

Who they invest alongside

The investors most often in the same rounds as Main Sequence Ventures. A count of rooms they were both in, not a relationship either has claimed.

In-Q-TelAccelerator10rounds togetherStartmateAccelerator9rounds togetherBlackbird VenturesVC firm7rounds togetherPossible VenturesVC firm7rounds togetherHorizons VenturesVC firm6rounds togetherUniseed VenturesVC firm5rounds togetherDCVCVC firm4rounds togetherHostplusPrivate equity4rounds togetheriSeedVC firm4rounds togetherAirtree VenturesVC firm3rounds togetherArtesian VCAsset manager3rounds togetherChevron Technology VenturesCorporate VC3rounds together

Recently backed

The latest companies Main Sequence Ventures put money into.

Kinoxis Therapeutics$4.8M · Sept 2026Amber Electric$56M · Sept 2026Universal Quantum$100M · Sept 2026Facet Amtech$2.2M · Aug 2026Emesent$15M · Jul 2026Number 8 bio$15K · Jun 2026

Mentioned on podcasts

Episodes that name Main Sequence Ventures in their description, not their title.

Quick answers about Main Sequence Ventures

What does Main Sequence Ventures invest in?

Main Sequence Ventures invests most often at Venture and Series A (56% of the rounds on record), in sectors such as Space, Climate and Technology.

How active is Main Sequence Ventures?

84 investments on record, 26 of them in the last 12 months, and it led 9. The most recent was in Sept 2026.

What has Main Sequence Ventures invested in recently?

Its most recent investments on record: Kinoxis Therapeutics (Sept 2026), Amber Electric (Series E, Sept 2026) and Metacognition AI (Pre-seed, Sept 2026).

How big are Main Sequence Ventures's cheques?

The median round it joins is $13M. It says it writes cheques of $250K to $20M.

Does Main Sequence Ventures lead rounds?

Sometimes: it led 9 of its 84 investments on record (11%).

Where does Main Sequence Ventures invest?

Most of the companies it backs are in Australia (92%).

Is Main Sequence Ventures investing now?

Yes: it is actively investing, with 26 investments in the last 12 months.

Who does Main Sequence Ventures invest alongside?

Most often In-Q-Tel (10 rounds together), Startmate (9 rounds together) and Blackbird Ventures (7 rounds together).

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Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it