United States · Investor

Longitude Capital

Last cheque observed Jun 2026; 97 cheques on record.

Deploying nowNew fund $100M, Nov 2025VC firm

SeedSeries ASeries BMed DeviceMedical DevicesHealth

Deploying now
70%of best year7cheques in 12 months, 97 on record
Since the last cheque135days00hrs00min00sec
Median round$60MCheque size, as they say$100K – $5.0MRounds led0 of 97Sole investor10 roundsExits4 from the portfolioMostly inUnited States, 89%
Pitch Longitude Capital

Longitude Capital highlights

  1. 01

    7 cheques in the last 12 months

  2. 02

    Mostly Series A and Venture: 49% of its rounds

  3. 03

    Sole investor in 10 rounds, median $17M

  4. 04

    4 exits from the portfolio

What they do

Longitude Capital specializes in making venture growth investments in biotechnology, medical technology, and health solutions companiesFrom their own website
Type
VC firm (from a list, unverified)
Cheque size
$100K – $5.0M as they say
Stages
SeedSeries ASeries BGrowthPre-IPO
Sectors
Med DeviceMedical DevicesHealth
Based in
Menlo Park, United States
Cold pitches
Not stated

The record

Every round we can evidence, newest first97 appearances

  1. 2026

    5 rounds

  2. Jun
    cAMPfield Therapeutics, Inc.Series A · US · Frazier Life Sciences$180MWith 7 others
  3. Apr
    VeraDermicsUS$384MWith 3 others
  4. Mar
    Polares MedicalSeries C · US$50MWith 2 others
  5. Jan
    AirNexis TherapeuticsSeries A · US$200MWith 2 others
  6. Jan
    Ventaris SurgicalSeries A · US · Firms' own news pages$30MWith 4 others
  7. 2025

    8 rounds

  8. Dec
  9. Dec
    Vera TherapeuticsUS$261MWith 3 others
  10. Sept
    Nalu MedicalVenture · US$50MWith 3 others
  11. May
    Cohere HealthSeries C · US$90MWith 4 others
  12. Mar
    MicroTransponderSeries F · US$65MSole investor
  13. Jan
    Rivus PharmaceuticalsVenture · US$57MWith 2 others
  14. Jan
    Helicore BiopharmaSeries A · US$65MWith 3 others
  15. Jan
    89bioUS$288MWith 2 others
  16. 2024

    7 rounds

  17. Nov
    Alentis TherapeuticsSeries D · CH · Avego Management$181MWith 11 others
  18. Nov
    CorticaVenture · IL$80MWith 5 others
  19. Sept
    CuraSen TherapeuticsVenture · US$5.8MSole investor
  20. Sept
    OrsoBioSeries B · US$67MWith 2 others
  21. Jun
    EndogenexSeries C · US · Hatteras Venture Partners$88MWith 6 others
  22. May
    Zenas BioPharmaSeries C · US · Tellus BioVentures$200MWith 14 others
  23. Jan
    Nalu MedicalSeries E · US$85MWith 1 other
  24. 2023

    4 rounds

  25. Dec
    Lassen TherapeuticsSeries B · US$85MWith 2 others
  26. Aug
    Poseida TherapeuticsUS$25MWith 4 others
  27. May
    Quanta TherapeuticsSeries D · US$51MWith 1 other
  28. Jan
    NOCDSeries B · US · Cigna Ventures$34MWith 6 others
  29. 2022

    10 rounds

  30. Nov
    EargoUS$29MWith 4 others
  31. Nov
    Opna BioSeries A · CH$38MWith 2 others
  32. Nov
    AptinyxGrant · US$5.6MWith 3 others
  33. Oct
    TricidaDebt · US$125MWith 5 others
  34. Sept
    CeribellSeries C · US$50MWith 2 others
  35. Aug
  36. Apr
    IntelyCareSeries C · US$115MWith 2 others
  37. Apr
    LimFlow SASeries D · FR$39MWith 2 others
  38. Mar
    DascenaVenture · USUndisclosedWith 2 others
  39. Jan
    AvengeBioSeries A · US$45MWith 1 other
  40. 2021

    3 rounds

  41. Aug
    SydnexisSeries B · US$45MWith 1 other
  42. Apr
    Theseus PharmaceuticalsSeries B$100MWith 4 others
  43. Jan
    Zavante TherapeuticsVentureUndisclosedSole investor
  44. 2020

    2 rounds

  45. Oct
    AlphaeonVenture$20MSole investor
  46. Feb
    Aimmune Therapeutics$200MWith 4 others
  47. 2019

    7 rounds

  48. Dec
    Epirium BioSeries A · US · Startuparound$85MWith 5 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

The team

Named by the firm itself, on a filing, its Form ADV or its company registration5 named

CECarolyn Elizabeth HelmsManaging Director / Chief Financial Officer of Longitude Capital Management Co., LLCiForm ADV
CBCristiana Blauth OliveiraChief Compliance Officer of Longitude Capital Management Co., LLCiForm ADV
JPJuliet Priscilla TammenomsbakkerManaging Member of Longitude Capital Management Co., LLCiForm ADV
JTJuliet Tammenoms BakkerManaging Member of the General PartneriFiling they signed
PGPatrick Gerald EnrightManaging Member of Longitude Capital Management Co., LLCiForm ADV

We also hold 25 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

What the register says

From the firm's own filings with the SEC, which it must file accurately by law

$2.4Bassets it managesOct 2026
Registeredinvestment adviserfull reporting to the SEC
Legal name
Longitude Capital Management Co., LLC
SEC number
CRD 161916

Funds on its Form ADV

5 private funds, $1.7B in gross assets · filed Mar 2024

  1. Longitude Venture Partners IV, L.P.Venture80 investors$639M
  2. Longitude Venture Partners III, L.P.Venture70 investors$459M
  3. Longitude Venture Partners V, L.P.Venture50 investors$336M
  4. Longitude Prime Fund, L.P.Venture35 investors$142M
  5. Longitude Venture Partners II, L.P.Venture50 investors$95M

What they claim to have backed

From their own portfolio page (on their website)

39 of 60 we have independently watched raise

89bioAlentisAvengebioAxonicsBioagelabsCeribellCgoncologyCheckmatepharmaCoherehealthCurasenDascenaEargoEndeavorbiomedicinesEpiriumFire1foundryHelomicsInfinanthealthInflazomeInozymeIntelycareLassentherapeuticsLimflowMicrotransponderMurjOpnabioOrbustherapeuticsOrsobioPolaresmedicalPoseidaPracticefusionSomatusSydnexisTourmalinebioTricidaVaxcyteVentarissurgicalVenusconceptVeradermicsWelbehealthA9oncologyAeonbiopharmaAimmuneAirnexisAkebiaAmarincorpAssemblybioBaronovaBoltmedCollegiumpharmaCorceptCorticacareCrownwheelpartnersEsperionGenerateHelicoreJazzpharmaKestramedicalMirumpharmaNabrivaNalumedand 9 more

Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.

Exits from the portfolio

Companies it backed that were later bought or listed4 in all

AqueSysBought by Allergan$300MSept 2015
Civitas TherapeuticsBought by Acorda Therapeutics$525MSept 2014
PreCision DermatologyBought by Valeant Pharmaceuticals International$500MFeb 2014
Solta MedicalBought by Valeant Pharmaceuticals International$250MDec 2013

An exit counts when it came after the firm's first round in the company. From historical deal records.

Who they invest alongside

The investors most often in the same rounds as Longitude Capital. A count of rooms they were both in, not a relationship either has claimed.

Recently backed

The latest companies Longitude Capital put money into.

Quick answers about Longitude Capital

What does Longitude Capital invest in?

Longitude Capital invests most often at Series A and Venture (49% of the rounds on record), in sectors such as Med Device, Medical Devices and Health.

How active is Longitude Capital?

97 investments on record, 7 of them in the last 12 months. The most recent was in Jun 2026.

What has Longitude Capital invested in recently?

Its most recent investments on record: cAMPfield Therapeutics, Inc. (Series A, Jun 2026), VeraDermics (Undisclosed round, Apr 2026) and Polares Medical (Series C, Mar 2026).

How big are Longitude Capital's cheques?

The median round it joins is $60M. It says it writes cheques of $100K to $5.0M.

Does Longitude Capital lead rounds?

Rarely, if at all: none of its 97 investments on record names it as the lead.

Where does Longitude Capital invest?

Most of the companies it backs are in the United States (89%) and Switzerland (6%).

Is Longitude Capital investing now?

Yes: it is actively investing, with 7 investments in the last 12 months.

Who does Longitude Capital invest alongside?

Most often RA Capital Management (14 rounds together), OrbiMed (10 rounds together) and Kleiner Perkins Caufield & Byers (7 rounds together).

Raising now?

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Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it