United States · Investor

2048 Ventures

Last cheque observed Sep 2026; 61 cheques on record.

Deploying nowNew fund $82M, Mar 2026VC firm

Pre-seedPharmaceuticalsArtificial IntelligenceTherapeutics

Deploying now
60%of best year9cheques in 12 months, 61 on record
Since the last cheque60days00hrs00min00sec
Median round$3.8MCheque size, as they say$300K – $2.0MRounds led1 of 61Sole investor9 roundsMostly inUnited States, 80%
Pitch 2048 Ventures

2048 Ventures highlights

  1. 01

    9 cheques in the last 12 months

  2. 02

    Mostly Seed and Pre-seed: 60% of its rounds

  3. 03

    Sole investor in 9 rounds, median $1.1M

What they do

Type
VC firm (from a list, unverified)
Cheque size
$300K – $2.0M as they say
Stages
Pre-seed
Sectors
PharmaceuticalsArtificial IntelligenceTherapeutics
Based in
New York, United States
Cold pitches
Not stated

The record

Every round we can evidence, newest first61 appearances

  1. 2026

    9 rounds

  2. Sept
    TwoStep TherapeuticsSeries A · US$63MWith 2 others
  3. Jul
    Genius AIGrowth · US · Ventureburn$44MWith 7 others
  4. Jul
    NebexSeed · US · TechStartups$30MWith 12 others
  5. May
    WirestockSeries A · US · TechCrunch$23MWith 6 others
  6. May
    Century HealthSeed · US$5.0MWith 4 others
  7. May
    FazeshiftSeries A · US$4.0MWith 4 others
  8. May
    RelySeed · US$4.5MWith 1 other
  9. Mar
    PocketPre-seed · US$1.4MSole investor
  10. Jan
    TwoStep TherapeuticsSeries A · US$21MWith 2 others
  11. 2025

    14 rounds

  12. Oct
    Caravel BioGrant · US$7.8MWith 3 others
  13. Oct
    EnurgenSeed · CA$4.1MWith 2 others
  14. Sept
    Nionyx BioSeed · US$4.0MWith 1 other
  15. Sept
    WarecloudsVenture · CLUndisclosedSole investor
  16. Aug
    PageportSeed · US$3.3MWith 2 others
  17. Aug
    Inso BiosciencesVenture · USUndisclosedWith 3 others
  18. Jul
    Romix BiosciencesPre-seed · US$600KSole investor
  19. Jun
    KascaidPre-seed · US$2.3MWith 3 others
  20. May
    Nimbus HealthSeed · US$12MWith 1 other
  21. Apr
    Rondah AIPre-seed · US$1.8MWith 1 other
  22. Apr
    AdaptisSeed · CA$4.0MWith 3 others
  23. Apr
    GroundfloorVenture · USUndisclosedWith 3 others
  24. Apr
    Rondah AIPre-seed · US$3.5MWith 1 other
  25. Feb
    Humane GenomicsSeed · US$4.0MWith 3 others
  26. 2024

    12 rounds

  27. Nov
    ImpiloSeries A · US$12MWith 2 others
  28. Oct
    PsyrinPre-seed · US$1.0MWith 3 others
  29. Sept
    FrateSeed · CA$2.6MWith 2 others
  30. May
    FemTherapeutics, Inc.Venture · CAUndisclosedWith 3 others
  31. May
    AerodomeSeries A · US$22MWith 4 others
  32. Apr
    Tetsuwan ScientificPre-seed · US$2.7MWith 1 other
  33. Apr
    Centro CommerceVenture · CAUndisclosedWith 3 others
  34. Apr
    ImpackedSeed · US$4.7MWith 4 others
  35. Mar
    Century HealthPre-seed · US$2.0MWith 2 others
  36. Feb
    Ripple AIPre-seed · US$1.2MSole investor
  37. Feb
    Neobe TherapeuticsSeed · GB$2.3MWith 1 other
  38. Jan
    Acorn FinanceSeries A · US$5.0MWith 4 others
  39. 2023

    7 rounds

  40. Dec
    AtlasSeed · US$2.7MSole investor
  41. Nov
    mealcoVenture · USUndisclosedWith 2 others
  42. Aug
    SupademoPre-seed · US$1.0MSole investor
  43. Jun
    AclidSeed · US$3.3MSole investor
  44. Jun
    PassageSeed · CA$30MWith 2 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

The team

Named by the firm itself, on a filing, its Form ADV or its company registration3 named

AIAlex IskoldManaging DirectoriFiling they signed
AVAlexander V IskoldManager and MemberiForm ADV
PSPaul SethiManaging PartneriFiling they signed

We also hold 7 people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

What the register says

From the firm's own filings with the SEC, which it must file accurately by law

$226Mgross assets of its fundsOct 2026
Exemptreporting adviserventure or small private funds
Legal name
2048 Ventures, LLC
SEC number
CRD 305237

Who they invest alongside

The investors most often in the same rounds as 2048 Ventures. A count of rooms they were both in, not a relationship either has claimed.

Recently backed

The latest companies 2048 Ventures put money into.

Quick answers about 2048 Ventures

What does 2048 Ventures invest in?

2048 Ventures invests most often at Seed and Pre-seed (60% of the rounds on record), in sectors such as Pharmaceuticals, Artificial Intelligence and Therapeutics.

How active is 2048 Ventures?

61 investments on record, 9 of them in the last 12 months, and it led 1. The most recent was in Sept 2026.

What has 2048 Ventures invested in recently?

Its most recent investments on record: TwoStep Therapeutics (Series A, Sept 2026), Genius AI (Growth, Jul 2026) and Nebex (Seed, Jul 2026).

How big are 2048 Ventures's cheques?

The median round it joins is $3.8M. It says it writes cheques of $300K to $2.0M.

Does 2048 Ventures lead rounds?

Sometimes: it led 1 of its 61 investments on record (2%).

Where does 2048 Ventures invest?

Most of the companies it backs are in the United States (80%) and Canada (15%).

Is 2048 Ventures investing now?

Yes: it is actively investing, with 9 investments in the last 12 months.

Who does 2048 Ventures invest alongside?

Most often Flybridge (5 rounds together), Everywhere Ventures (4 rounds together) and Plug and Play (4 rounds together).

Raising now?

Find the investors who back rounds like yours, and keep every conversation on one fundraising board.

Built from the rounds we watched, its filings and its own website, refreshed every night. How we count · Report a correction · Is this your firm? Claim it