Top list · San Francisco
141 Web3 & Crypto startups in San Francisco have raised money in rounds we track. These are the 50 that have raised the most, $2.9B between them.
Ripple is a leading American technology company focused on enhancing global cross-border payments through blockchain technology.
Founded 2012San Francisco, United States$596Mlast round Nov 2025Kite augments coding environment with the use of internet’s programming knowledge and machine learning.
Founded 2014San Francisco, United States$236Mlast round Sept 2025Discord is an online voice, video, and text communication platform designed for creating communities.
Founded 2015San Francisco, United States$200Mlast round Mar 2024World connects users through a privacy-focused network with secure digital asset management.
Founded -San Francisco, United States$188Mlast round Jul 2026CoinTracker is a financial technology company that specializes in cryptocurrency portfolio tracking and tax compliance software.
Founded 2017San Francisco, United States$102Mlast round Jan 2022Anchorage Digital is a prominent financial technology and Web3 infrastructure company based in San Francisco, California.
Founded 2017San Francisco, United States$100Mlast round Feb 2026Orange DAO is community venture capital.
Founded -San Francisco, United States$80Mlast round Aug 2022TRM Labs is a blockchain intelligence company based in San Francisco, founded in 2018.
Founded 2018San Francisco, United States$74Mlast round Feb 2026Lightning Labs is a private technology company focused on enhancing the Bitcoin ecosystem through the Lightning Network, a second-layer payment protocol designe
Founded 2016San Francisco, United States$70Mlast round Apr 20220x is a blockchain technology company based in San Francisco, founded in 2016 by Will Warren and Amir Bandeali.
Founded 2016San Francisco, United States$70Mlast round Apr 2022Chia Network is a blockchain technology company based in South San Francisco, founded in 2017 by Bram Cohen and Ryan Singer.
Founded 2017San Francisco, United States$61Mlast round May 2021Eco provides a digital cryptocurrency platform that can be used as a payment tool for daily-use transactions.
Founded 2018San Francisco, United States$60Mlast round Jul 2021Figure Markets is a company that uses blockchain technology to construct the future of private capital markets.
Founded 2024San Francisco, United States$60Mlast round Mar 2024Succinct builds zero-knowledge infrastructure for developers.
Founded 2022San Francisco, United States$55Mlast round Mar 2024Layer1 is a company focused on crypto and digital asset infrastructure.
Founded 2018San Francisco, United States$52Mlast round Oct 2019Desarrollá las economías on-chain con Ripio: stablecoins en moneda local, rampas instantáneas e infraestructura white-label para empresas en Latinoamérica.
Founded -San Francisco, United States$52Mlast round Sept 2021Deca is a display and discovery infrastructure for NFTs.
Founded 2021San Francisco, United States$51Mlast round Nov 2025Pharos is an AI-powered healthcare startup founded in 2024 that focuses on automating hospital quality reporting.
Founded -San Francisco, United States$49Mlast round Apr 2026Veem is a San Francisco-based B2B payment platform founded in 2014.
Founded 2014San Francisco, United States$49Mlast round Sept 2018DataWallet operates a consumer-to-business marketplace which directly links businesses with internet users.
Founded 2015San Francisco, United States$40Mlast round Feb 2018Numerai is an innovative, AI-driven hedge fund based in San Francisco, California.
Founded 2015San Francisco, United States$40Mlast round Nov 2025Obex helps to fund stablecoin projects backed by compute, energy and fintech credit on the Sky protocol.
Founded -San Francisco, United States$37Mlast round Nov 2025Agoric is a blockchain product company founded in 2018 and based in San Francisco, California.
Founded 2018San Francisco, United States$36Mlast round Nov 2021MasterClass is a provider of an online education platform designed to offer video based vocational courses.
Founded 2015San Francisco, United States$35Mlast round Jul 2021Courtyard is a blockchain-powered marketplace and tokenization service tailored for modern collectors.
Founded 2021San Francisco, United States$30Mlast round Jul 2025Solana is the high performance network powering internet capital markets, payments, and crypto applications.
Founded -San Francisco, United States$30Mlast round Jan 2025Earn amplified yield on Ethereum and stablecoins with Origin Protocol&s OETH and OUSD.
Founded 2017San Francisco, United States$29Mlast round Apr 2018Crypto Unicorns is a California-based entertainment company that develops and publishes blockchain-based games.
Founded 2022San Francisco, United States$26Mlast round Mar 2022Chronicled builds trust and automation in the life science industry, powered by blockchain.
Founded 2014San Francisco, United States$26Mlast round Feb 2022DRiP creates creator-centric Web3 content distribution network and offers free digital gifts from well-known producers.
Founded 2023San Francisco, United States$25Mlast round Jun 2026Valinor Enterprises Inc.
Founded -San Francisco, United States$25Mlast round Mar 2026Portal to Bitcoin is a fintech and Web3 company based in San Francisco, founded in 2018.
Founded 2018San Francisco, United States$25Mlast round Dec 2025Irreducible, based in San Francisco, California, is a cryptography startup founded in 2022.
Founded 2022San Francisco, United States$24Mlast round Jan 2025Thirdweb is a full-stack, open-source Web3 development platform that facilitates the creation, deployment, and scaling of decentralized applications (dApps), ga
Founded -San Francisco, United States$24Mlast round Aug 2022Libra is a specialized platform that provides expert insights, breaking news, and comprehensive guides on cryptocurrency taxation and regulatory compliance.
Founded 2014San Francisco, United States$23Mlast round Aug 2018Goldsky is a San Francisco-based Web3 developer platform founded in 2021.
Founded 2021San Francisco, United States$21Mlast round Sept 2022Ambient is an AI-powered assistant designed for leadership teams and operators, particularly Chiefs of Staff and Heads of Operations.
Founded 2023San Francisco, United States$20Mlast round Mar 2025Ithaca is a crypto-powered firm that primarily focuses on advancing and accelerating the cryptocurrency frontier.
Founded -San Francisco, United States$20Mlast round Oct 2024Commonwealth Labs is a governance startup offering a new twist on token airdrops.
Founded 2018San Francisco, United States$20Mlast round May 2022TrustToken is a financial company that provides reinventing financial infrastructure services.
Founded 2017San Francisco, United States$20Mlast round Jun 2018CoinList is a digital asset platform designed for early adopters interested in investing in and trading leading cryptocurrency projects.
Founded 2017San Francisco, United States$19Mlast round Jan 2022We're improving the way we communicate on the web, utilizing machine learning to detect online abuse and harassment.
Founded 2017San Francisco, United States$18Mlast round Oct 2025ProvLabs is a fintech company that offers blockchain SaaS solutions for financial institutions.
Founded -San Francisco, United States$18Mlast round Nov 2024CipherOwl is an AI-powered intelligence platform focused on institutional cryptocurrency compliance and on-chain data analysis.
Founded 2024San Francisco, United States$15Mlast round Oct 2025Blocknative is a provider of real-time blockchain transaction management and monitoring solutions for public blockchain networks.
Founded 2018San Francisco, United States$15Mlast round Dec 2022Unto Labs is a blockchain software company based in San Francisco, founded in 2024.
Founded 2024San Francisco, United States$14Mlast round Apr 2025Zerion is a Web3 financial technology company based in San Francisco, California.
Founded 2019San Francisco, United States$14Mlast round Oct 2022The Easy Company is a software company based in San Francisco, founded in 2021.
Founded 2009San Francisco, United States$14Mlast round Jan 2023Set Labs is a blockchain and fintech company founded in January 2017 and based in San Francisco, California.
Founded 2017San Francisco, United States$14Mlast round May 2021Kresus is an open-source, privacy-focused personal finance manager built on Web3 technologies.
Founded 2021San Francisco, United States$13Mlast round Feb 2026Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
Open any company for its rounds and investors, or search the investors who back Web3 & Crypto startups in San Francisco in the app, with filters, lists and exports.
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PWeb3 & Crypto startups in the United States1,080 companies · $39B
YLBGWeb3 & Crypto startups founded in 2021427 companies · $4.1B
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SAWeb3 & Crypto startups founded in 2022269 companies · $4.8B
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SWeb3 & Crypto startups that raised in 2026233 companies · $15B in 2026
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BWeb3 & Crypto startups founded in 2018223 companies · $4.2B
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FWeb3 & Crypto startups founded in 2020174 companies · $4.7B
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NWeb3 & Crypto startups in New York172 companies · $11B
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TMStartups in San Francisco4,251 companies · $350B
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TMAI startups in San Francisco1,276 companies · $321B
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ABig Data & Analytics startups in San Francisco300 companies · $47B
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ZHealthcare startups in San Francisco230 companies · $9.2B
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IInternet startups in San Francisco192 companies · $20B
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CSoftware startups in San Francisco189 companies · $48B
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CHBiotech startups in San Francisco181 companies · $12B