Top list · San Francisco

Biotech startups in San Francisco

181 biotech startups in San Francisco have raised money in rounds we track. These are the 50 that have raised the most, $12B between them.

$12Braised by these 50
181on our record in all
Mirendilraised the most
  1. 1MirendilMirendil is an AI research lab that creates self-accelerating systems that convert computing power into scientific advancements.

    Mirendil is an AI research lab that creates self-accelerating systems that convert computing power into scientific advancements.

    Founded -San Francisco, United States$1.4Blast round Nov 2026
  2. 2Apogee TherapeuticsApogee Therapeutics is a biotechnology company that offers therapies for immunological and inflammatory disorders.

    Apogee Therapeutics is a biotechnology company that offers therapies for immunological and inflammatory disorders.

    Founded 2022San Francisco, United States$1.3Blast round May 2026
  3. 3Collective HealthCollective Health is an independent third-party administrator and integrated health benefits platform founded in 2013.

    Collective Health is an independent third-party administrator and integrated health benefits platform founded in 2013.

    Founded 2013San Francisco, United States$720Mlast round May 2021
  4. 4Denali TherapeuticsDenali Therapeutics is dedicated to defeating neurodegenerative diseases to deliver safe and effective medicines to patients and families.

    Denali Therapeutics is dedicated to defeating neurodegenerative diseases to deliver safe and effective medicines to patients and families.

    Founded 2013San Francisco, United States$547Mlast round Dec 2025
  5. 5Chai DiscoveryChai Discovery is an artificial intelligence biotechnology company based in San Francisco, California, founded in March 2024.

    Chai Discovery is an artificial intelligence biotechnology company based in San Francisco, California, founded in March 2024.

    Founded -San Francisco, United States$530Mlast round Jul 2026
  6. 6Hinge HealthHinge Health is a digital clinic for joint, and muscle care, pelvic pain, bowel, and bladder control.

    Hinge Health is a digital clinic for joint, and muscle care, pelvic pain, bowel, and bladder control.

    Founded 2015San Francisco, United States$434Mlast round Oct 2021
  7. 789Bio89bio is a biopharmaceutical company that develops clinical-stage therapies for liver and cardiometabolic diseases.

    89bio is a biopharmaceutical company that develops clinical-stage therapies for liver and cardiometabolic diseases.

    Founded 2018San Francisco, United States$348Mlast round Jan 2025
  8. 8AlumisAlumis is a precision medicine company focused on the discovery, development and treatment of autoimmune disorders.

    Alumis is a precision medicine company focused on the discovery, development and treatment of autoimmune disorders.

    Founded 2021San Francisco, United States$345Mlast round Jan 2026
  9. 9Dice TherapeuticsDice Therapeutics is a clinical-stage biopharmaceutical company that makes medicines for chronic autoimmune and inflammatory diseases.

    Dice Therapeutics is a clinical-stage biopharmaceutical company that makes medicines for chronic autoimmune and inflammatory diseases.

    Founded 2013San Francisco, United States$345Mlast round Oct 2022
  10. 10BrainCoBrain Co.

    Brain Co.

    Founded -San Francisco, United States$292Mlast round Jan 2026
  11. 11Expedition TherapeuticsExpedition Therapeutics is a biotechnology company based in San Francisco, founded in 2024.

    Expedition Therapeutics is a biotechnology company based in San Francisco, founded in 2024.

    Founded 2024San Francisco, United States$280Mlast round Aug 2026
  12. 12Merge LabsMerge Labs provides a single API to connect software applications with multiple third-party platforms.

    Merge Labs provides a single API to connect software applications with multiple third-party platforms.

    Founded 2016San Francisco, United States$252Mlast round Jan 2026
  13. 13Nurix TherapeuticsNurix Therapeutics is a biopharmaceutical company that focuses on the development and discovery of small molecule drugs.

    Nurix Therapeutics is a biopharmaceutical company that focuses on the development and discovery of small molecule drugs.

    Founded 2012San Francisco, United States$250Mlast round Oct 2025
  14. 14AlectorAlector is a biopharmaceutical company that develops therapies for the treatment of neurodegeneration diseases.

    Alector is a biopharmaceutical company that develops therapies for the treatment of neurodegeneration diseases.

    Founded 2013San Francisco, United States$215Mlast round Nov 2024
  15. 15Omada HealthOmada Health is a digital behavioral medicine company that helps members change their mindsets to improve health and build lasting change.

    Omada Health is a digital behavioral medicine company that helps members change their mindsets to improve health and build lasting change.

    Founded 2011San Francisco, United States$200Mlast round May 2025
  16. 16Marea TherapeuticsMarea is a biotechnology firm that uses the advancements in human genetics next-generation medications for cardiometabolic illnesses.

    Marea is a biotechnology firm that uses the advancements in human genetics next-generation medications for cardiometabolic illnesses.

    Founded 2022San Francisco, United States$190Mlast round Jun 2024
  17. 17Osanni BioOsanni Bio is a biotechnology company developing therapies aimed at preventing and reversing blindness caused by retinal diseases.

    Osanni Bio is a biotechnology company developing therapies aimed at preventing and reversing blindness caused by retinal diseases.

    Founded -San Francisco, United States$190Mlast round Jun 2026
  18. 18Braveheart BioBraveheart Bio is a clinical-stage biotechnology company focused on developing precision therapies in the cardiovascular disease space.

    Braveheart Bio is a clinical-stage biotechnology company focused on developing precision therapies in the cardiovascular disease space.

    Founded -San Francisco, United States$185Mlast round Nov 2025
  19. 19BenchlingBenchling is a cloud-based platform for biotechnology research and development and the only biology-first platform for scientific data, collaboration, and insights.

    Benchling is a cloud-based platform for biotechnology research and development and the only biology-first platform for scientific data, collaboration, and insights.

    Founded 2012San Francisco, United States$162Mlast round Nov 2021
  20. 20Doctor on DemandDoctor On Demand is a nationwide virtual healthcare provider based in San Francisco, offering 24/7 access to board-certified physicians, licensed psychiatrists,

    Doctor On Demand is a nationwide virtual healthcare provider based in San Francisco, offering 24/7 access to board-certified physicians, licensed psychiatrists,

    Founded 2013San Francisco, United States$161Mlast round Apr 2018
  21. 21GingerGinger is an on-demand mental health company providing around-the-clock access to emotional support via coaching, therapy, and psychiatry.

    Ginger is an on-demand mental health company providing around-the-clock access to emotional support via coaching, therapy, and psychiatry.

    Founded 2011San Francisco, United States$155Mlast round Mar 2021
  22. 22Tenaya TherapeuticsTenaya Therapeutics is a developer of novel therapies designed to offer treatment for heart disease.

    Tenaya Therapeutics is a developer of novel therapies designed to offer treatment for heart disease.

    Founded 2016San Francisco, United States$152Mlast round Dec 2025
  23. 23SepternaSepterna is a biotech firm unlocking diverse drug discovery potential in G protein-coupled receptors across various diseases.

    Septerna is a biotech firm unlocking diverse drug discovery potential in G protein-coupled receptors across various diseases.

    Founded 2022San Francisco, United States$150Mlast round Jul 2023
  24. 24Vir BiotechnologyVir Biotechnology is an immunology company that develops products to treat and prevent infectious diseases and other serious conditions.

    Vir Biotechnology is an immunology company that develops products to treat and prevent infectious diseases and other serious conditions.

    Founded 2016San Francisco, United States$150Mlast round Feb 2026
  25. 25CaresyntaxCaresyntax is a healthcare technology company founded in 2013, specializing in surgical intelligence.

    Caresyntax is a healthcare technology company founded in 2013, specializing in surgical intelligence.

    Founded 2013San Francisco, United States$144Mlast round Aug 2024
  26. 26CalmCalm, officially known as Calm.com, Inc., is a prominent American software company based in San Francisco, California.

    Calm, officially known as Calm.com, Inc., is a prominent American software company based in San Francisco, California.

    Founded 2012San Francisco, United States$143Mlast round Jul 2019
  27. 27NexHealthNexHealth is a healthcare technology company founded in 2017, based in San Francisco, California.

    NexHealth is a healthcare technology company founded in 2017, based in San Francisco, California.

    Founded 2017San Francisco, United States$129Mlast round Apr 2022
  28. 28Ouro MedicinesOuro Medicines is a biotechnology company based in South San Francisco, established in 2025 by Monograph Capital in partnership with GSK.

    Ouro Medicines is a biotechnology company based in South San Francisco, established in 2025 by Monograph Capital in partnership with GSK.

    Founded 2024San Francisco, United States$120Mlast round Jan 2025
  29. 29Cricket HealthCricket Health is a specialty kidney care provider of integrated nephrology and dialysis care.

    Cricket Health is a specialty kidney care provider of integrated nephrology and dialysis care.

    Founded 2015San Francisco, United States$110Mlast round Aug 2021
  30. 30T-knife TherapeuticsT-knife Therapeutics is a biopharmaceutical company focused on developing innovative T cell receptor (TCR) engineered T cell therapies for solid tumors.

    T-knife Therapeutics is a biopharmaceutical company focused on developing innovative T cell receptor (TCR) engineered T cell therapies for solid tumors.

    Founded 2019San Francisco, United States$110Mlast round Oct 2025
  31. 31Character BiosciencesCharacter Biosciences is a precision medicine company founded between 2018 and 2019, focusing on transforming drug development for progressive, polygenic diseas

    Character Biosciences is a precision medicine company founded between 2018 and 2019, focusing on transforming drug development for progressive, polygenic diseas

    Founded 2019San Francisco, United States$110Mlast round Sept 2025
  32. 32Presidio PharmaceuticalsPresidio Pharmaceuticals is a clinical-stage pharmaceutical company focused on the discovery of small-molecule antiviral therapeutics.

    Presidio Pharmaceuticals is a clinical-stage pharmaceutical company focused on the discovery of small-molecule antiviral therapeutics.

    Founded 2006San Francisco, United States$109Mlast round Jun 2014
  33. 33Aligos TherapeuticsAligos Therapeutics is discovering and developing new classes of molecules that interact directly with disease-causing modalities.

    Aligos Therapeutics is discovering and developing new classes of molecules that interact directly with disease-causing modalities.

    Founded 2018San Francisco, United States$105Mlast round Feb 2025
  34. 34Vida HealthVida Health is a virtual care provider specializing in personalized obesity and cardiometabolic care.

    Vida Health is a virtual care provider specializing in personalized obesity and cardiometabolic care.

    Founded 2014San Francisco, United States$102Mlast round Nov 2023
  35. 35Codiak BiosciencesCodiak is a clinical-stage biopharmaceutical company focused on pioneering the development of exosome-based therapeutics.

    Codiak is a clinical-stage biopharmaceutical company focused on pioneering the development of exosome-based therapeutics.

    Founded 2015San Francisco, United States$100Mlast round Sept 2022
  36. 36Neuron23Neuron23 is a developer of drugs intended to treat Parkinson's disease and Alzheimer's disease.

    Neuron23 is a developer of drugs intended to treat Parkinson's disease and Alzheimer's disease.

    Founded 2018San Francisco, United States$99Mlast round Jun 2026
  37. 37AtomwiseAtomwise is a technology-enabled pharmaceutical company that focuses on small-molecule drug discovery using deep learning.

    Atomwise is a technology-enabled pharmaceutical company that focuses on small-molecule drug discovery using deep learning.

    Founded 2012San Francisco, United States$97Mlast round Jan 2024
  38. 38Concentric AnalgesicsConcentric Analgesics is a biotechnology company that develops non-opioid therapeutics for the management of acute and chronic pain.

    Concentric Analgesics is a biotechnology company that develops non-opioid therapeutics for the management of acute and chronic pain.

    Founded 2014San Francisco, United States$96Mlast round Jan 2022
  39. 39Incredible HealthIncredible Health is the largest AI-powered healthcare career marketplace in the United States, dedicated to connecting healthcare employers with permanent nurs

    Incredible Health is the largest AI-powered healthcare career marketplace in the United States, dedicated to connecting healthcare employers with permanent nurs

    Founded 2017San Francisco, United States$95Mlast round Aug 2022
  40. 40Firefly BioFirefly Bio specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.

    Firefly Bio specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.

    Founded 2022San Francisco, United States$94Mlast round Feb 2024
  41. 41Two ChairsTwo Chairs is a hybrid behavioral health provider founded in 2017 by Alex Katz, headquartered in San Francisco, California.

    Two Chairs is a hybrid behavioral health provider founded in 2017 by Alex Katz, headquartered in San Francisco, California.

    Founded 2017San Francisco, United States$93Mlast round Apr 2024
  42. 42AugmedixAugmedix, a Commure company, empowers clinicians to connect with patients by liberating them from administrative burden through the power of ambient AI, data, and trust.

    Augmedix, a Commure company, empowers clinicians to connect with patients by liberating them from administrative burden through the power of ambient AI, data, and trust.

    Founded 2018San Francisco, United States$90Mlast round Nov 2023
  43. 43Frontier MedicinesFrontier Medicines is a biopharmaceutical company that develops a chemoproteomics platform to accelerate the development of medicines.

    Frontier Medicines is a biopharmaceutical company that develops a chemoproteomics platform to accelerate the development of medicines.

    Founded 2018San Francisco, United States$87Mlast round Jun 2024
  44. 44Stride HealthStride Health is a provider of an insurance recommendation platform designed to offer health insurance services.

    Stride Health is a provider of an insurance recommendation platform designed to offer health insurance services.

    Founded 2013San Francisco, United States$86Mlast round Oct 2021
  45. 45Modern HealthModern Health is a global mental wellness platform founded in 2017 by Alyson Watson and Erica Johnson, headquartered in San Francisco, California.

    Modern Health is a global mental wellness platform founded in 2017 by Alyson Watson and Erica Johnson, headquartered in San Francisco, California.

    Founded 2017San Francisco, United States$85Mlast round Feb 2021
  46. 46PhilMedication Access, Simplified.

    Medication Access, Simplified.

    Founded 2015San Francisco, United States$85Mlast round Jul 2025
  47. 47PellePharmPellePharm is a biotechnology company dedicated to developing treatments for rare dermatologic diseases, with a particular focus on Gorlin syndrome and basal ce

    PellePharm is a biotechnology company dedicated to developing treatments for rare dermatologic diseases, with a particular focus on Gorlin syndrome and basal ce

    Founded 2016San Francisco, United States$78Mlast round Nov 2018
  48. 48ClearCareClear Care is now WellSky.

    Clear Care is now WellSky.

    Founded 2010San Francisco, United States$76Mlast round Aug 2016
  49. 49Viz.aiViz.ai is a healthcare AI company based in San Francisco, founded in 2016 by Dr.

    Viz.ai is a healthcare AI company based in San Francisco, founded in 2016 by Dr.

    Founded 2016San Francisco, United States$71Mlast round Oct 2019
  50. 50ProLynxProlynx is a clinical-stage biotechnology company based in the San Francisco Bay Area, founded in 2009.

    Prolynx is a clinical-stage biotechnology company based in the San Francisco Bay Area, founded in 2009.

    Founded 2009San Francisco, United States$70Mlast round Dec 2025
Total fundinghow the list is ranked
15 November 2026updated nightly
Rounds we tracksource: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

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