Top list · San Diego
Startups in San Diego
485 startups in San Diego have raised money in rounds we track. These are the 50 that have raised the most, $20B between them.
- 1
Shield AIShield AI is an artificial intelligence company that aims to protect service members and civilians with intelligent systems.Shield AI is an artificial intelligence company that aims to protect service members and civilians with intelligent systems.
Founded 2015San Diego, United States$7.0Blast round Nov 2026 - 2
Candid TherapeuticsCandid Therapeutics was a clinical-stage biotechnology company based in San Diego, California, founded in 2024.Candid Therapeutics was a clinical-stage biotechnology company based in San Diego, California, founded in 2024.
Founded 2024San Diego, United States$875Mlast round Mar 2026 - 3
Avidity BiosciencesSynapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.
Synapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.
Founded 2012San Diego, United States$790Mlast round Sept 2025 - 4
Maxwell PowerMaxwell Power is a renewable energy company that installs solar panels.Maxwell Power is a renewable energy company that installs solar panels.
Founded -San Diego, United States$750Mlast round Jun 2026 - 5
ErascaErasca is a developer of oncology drugs intended to provide precision oncology options.Erasca is a developer of oncology drugs intended to provide precision oncology options.
Founded 2018San Diego, United States$739Mlast round Jul 2026 - 6
LytxLytx develops video-based driver safety and fleet management solutions.Lytx develops video-based driver safety and fleet management solutions.
Founded 1998San Diego, United States$700Mlast round Apr 2018 - 7
Viking TherapeuticsViking Therapeutics is developing novel therapeutics for patients suffering from metabolic and endocrine disorders.Viking Therapeutics is developing novel therapeutics for patients suffering from metabolic and endocrine disorders.
Founded 2012San Diego, United States$635Mlast round Feb 2024 - 8
Gossamer BioGossamer Bio is a biopharmaceutical company focused on the discovery and development of novel and differentiated therapeutic products.Gossamer Bio is a biopharmaceutical company focused on the discovery and development of novel and differentiated therapeutic products.
Founded 2015San Diego, United States$567Mlast round Sept 2026 - 9
Applied Data FinanceADF has been purpose-built to be the optimal link between the underestimated underbanked consumer and capital markets.ADF has been purpose-built to be the optimal link between the underestimated underbanked consumer and capital markets.
Founded 2014San Diego, United States$539Mlast round Mar 2026 - 10
ClickUpClickUp is a productivity and work management platform that consolidates various tools into a single workspace.ClickUp is a productivity and work management platform that consolidates various tools into a single workspace.
Founded 2017San Diego, United States$525Mlast round Jul 2025 - 11
CybereasonCybereason is an endpoint detection and response platform that identifies cyber attacks for effective response.Cybereason is an endpoint detection and response platform that identifies cyber attacks for effective response.
Founded 2012San Diego, United States$509Mlast round Mar 2025 - 12Cidara TherapeuticsCidara Therapeutics is a biotechnology company that specializes in the fields of healthcare and therapeutics.
Cidara Therapeutics is a biotechnology company that specializes in the fields of healthcare and therapeutics.
Founded 2012San Diego, United States$463Mlast round Oct 2025 - 13
Artiva BiotherapeuticsArtiva Biotherapeutics is a biotech company focused on developing and commercializing allogeneic natural killer (NK) cell therapies.
Artiva Biotherapeutics is a biotech company focused on developing and commercializing allogeneic natural killer (NK) cell therapies.
Founded 2019San Diego, United States$420Mlast round May 2026 - 14
Belite BioBelite Bio is a clinical stage biopharmaceutical drug development company.Belite Bio is a clinical stage biopharmaceutical drug development company.
Founded 2018San Diego, United States$350Mlast round Dec 2025 - 15
KyribaKyriba is a leader in liquidity performance and SaaS treasury solutions, helping CFOs, Treasurers, and IT leaders manage and optimize their liquidity in complexKyriba is a leader in liquidity performance and SaaS treasury solutions, helping CFOs, Treasurers, and IT leaders manage and optimize their liquidity in complex
Founded 2000San Diego, United States$251Mlast round Mar 2019 - 16
Mirador TherapeuticsMirador Therapeutics is a clinical-stage precision medicine company based in San Diego, California.Mirador Therapeutics is a clinical-stage precision medicine company based in San Diego, California.
Founded 2024San Diego, United States$250Mlast round Jan 2026 - 17
WiliotWiliot is a startup based in Caesarea, Israel, with a business development presence in San Diego, US.Wiliot is a startup based in Caesarea, Israel, with a business development presence in San Diego, US.
Founded 2017San Diego, United States$235Mlast round Jul 2021 - 18
Poseida TherapeuticsPoseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics.Poseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics.
Founded 2014San Diego, United States$217Mlast round Aug 2023 - 19
GenomaticaGenomatica manufactures sustainable chemicals from renewable feedstocks.Genomatica manufactures sustainable chemicals from renewable feedstocks.
Founded 2000San Diego, United States$203Mlast round Oct 2018 - 20
DrataDrata is a compliance and security SaaS platform that automates the compliance workflows on a company's security controls.Drata is a compliance and security SaaS platform that automates the compliance workflows on a company's security controls.
Founded 2020San Diego, United States$200Mlast round Dec 2022 - 21
Element BiosciencesElement Biosciences is a biotechnology company based in San Diego, founded in 2017 by former Illumina scientists.Element Biosciences is a biotechnology company based in San Diego, founded in 2017 by former Illumina scientists.
Founded 2017San Diego, United States$190Mlast round Jun 2026 - 22
ViaCyteViaCyte is a cellular therapy and regenerative medicine company based in San Diego, California.ViaCyte is a cellular therapy and regenerative medicine company based in San Diego, California.
Founded -San Diego, United States$188Mlast round Nov 2018 - 23
aTyr PharmaaTyr Pharma (Nasdaq: LIFE) is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways.aTyr Pharma (Nasdaq: LIFE) is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways.
Founded -San Diego, United States$181Mlast round Mar 2015 - 24Capstan TherapeuticsCapstan Therapeutics is advancing cell engineering to develop therapeutics for a broad range of diseases.
Capstan Therapeutics is advancing cell engineering to develop therapeutics for a broad range of diseases.
Founded 2021San Diego, United States$175Mlast round Mar 2024 - 25
IQHQIQHQ is a commercial real estate developer that specializes in creating and developing effective environments and innovative homes.
IQHQ is a commercial real estate developer that specializes in creating and developing effective environments and innovative homes.
Founded 2019San Diego, United States$170Mlast round Aug 2025 - 26
Epic SciencesEpic Sciences is a diagnostics company improving cancer management by providing real-time biopsy material to guide personalized medicine.Epic Sciences is a diagnostics company improving cancer management by providing real-time biopsy material to guide personalized medicine.
Founded 2008San Diego, United States$165Mlast round Apr 2023 - 27
CloudbedsCloudbeds is a cloud-based hospitality management system (HMS) and property management system (PMS) that streamlines hotel operations, guest experiences, and reCloudbeds is a cloud-based hospitality management system (HMS) and property management system (PMS) that streamlines hotel operations, guest experiences, and re
Founded 2012San Diego, United States$162Mlast round Nov 2021 - 28
RayzeBioRayzeBio is a pharmaceuticals company that develops targeted radiopharmaceutical drugs for cancer.RayzeBio is a pharmaceuticals company that develops targeted radiopharmaceutical drugs for cancer.
Founded 2018San Diego, United States$160Mlast round Sept 2022 - 29
Engrail TherapeuticsEngrail Therapeutics is a clinical-stage pharmaceutical company based in San Diego, California, founded in 2019.Engrail Therapeutics is a clinical-stage pharmaceutical company based in San Diego, California, founded in 2019.
Founded 2019San Diego, United States$157Mlast round Mar 2024 - 30
Suneva MedicalSuneva Medical, Inc.Suneva Medical, Inc.
Founded 2009San Diego, United States$155Mlast round Jun 2016 - 31
3D Robotics3DR makes advanced drone technology easily accessible to the construction, mining, and surveying industries for use in data analysis.3DR makes advanced drone technology easily accessible to the construction, mining, and surveying industries for use in data analysis.
Founded 2009San Diego, United States$152Mlast round Apr 2017 - 32
Cerulean PharmaCerulean Pharma develops nanotechnology-based therapeutics for treating oncology, cardiovascular, autoimmune and inflammatory diseases.Cerulean Pharma develops nanotechnology-based therapeutics for treating oncology, cardiovascular, autoimmune and inflammatory diseases.
Founded 2006San Diego, United States$152Mlast round Apr 2015 - 33
SDRE HomebuyersSDRE Homebuyers is a real estate investment firm providing property development, property management, and real estate services.SDRE Homebuyers is a real estate investment firm providing property development, property management, and real estate services.
Founded 2020San Diego, United States$150Mlast round Jul 2025 - 34
Pathway PowerPathway Power is a utility-scale solar and battery storage developer building a renewable energy value chain.Pathway Power is a utility-scale solar and battery storage developer building a renewable energy value chain.
Founded 2022San Diego, United States$150Mlast round Jun 2026 - 35
Sidewinder TherapeuticsSidewinder Therapeutics is a biotechnology company that offers life-saving therapies for cancer and rare diseases.Sidewinder Therapeutics is a biotechnology company that offers life-saving therapies for cancer and rare diseases.
Founded 2023San Diego, United States$137Mlast round Apr 2026 - 36
TealiumTealium is a provider of customer data orchestration tools aimed to address challenges in online search, marketing, and segment targeting.Tealium is a provider of customer data orchestration tools aimed to address challenges in online search, marketing, and segment targeting.
Founded 2008San Diego, United States$133Mlast round May 2019 - 37
Endeavor BioMedicinesEndeavor BioMedicines is a clinical-stage biotechnology company based in San Diego, California, founded in 2019.Endeavor BioMedicines is a clinical-stage biotechnology company based in San Diego, California, founded in 2019.
Founded 2018San Diego, United States$133Mlast round Apr 2024 - 38
ApteraAptera Motors is an electric vehicle manufacturer that designs and develops aerodynamic electric vehicles.Aptera Motors is an electric vehicle manufacturer that designs and develops aerodynamic electric vehicles.
Founded 2006San Diego, United States$131Mlast round Oct 2025 - 39
Protego BiopharmaProtego Biopharma is a California-based biotechnology company that researches and develops small-molecule therapeutics for the treatment of protein misfolding diseases.Protego Biopharma is a California-based biotechnology company that researches and develops small-molecule therapeutics for the treatment of protein misfolding diseases.
Founded 2018San Diego, United States$130Mlast round Dec 2025 - 40
NetradyneNetradyne is a technology company based in San Diego, California, specializing in artificial intelligence, computer vision, and edge computing to enhance fleet Netradyne is a technology company based in San Diego, California, specializing in artificial intelligence, computer vision, and edge computing to enhance fleet
Founded 2015San Diego, United States$127Mlast round Jan 2025 - 41
Platform SciencePlatform Science is a technology company based in San Diego, founded in 2015.Platform Science is a technology company based in San Diego, founded in 2015.
Founded 2015San Diego, United States$125Mlast round Apr 2024 - 42
MeasurablMeasurabl develops an ESG data management platform for commercial real estate.Measurabl develops an ESG data management platform for commercial real estate.
Founded 2013San Diego, United States$122Mlast round May 2023 - 43
Aspen NeuroscienceAspen Neuroscience is a biotechnology company that specializes in personalized cell therapies.Aspen Neuroscience is a biotechnology company that specializes in personalized cell therapies.
Founded 2018San Diego, United States$122Mlast round Nov 2025 - 44
Escient PharmaceuticalsEscient Pharmaceuticals is a privately-held biotechnology company focusing on the advancement of G Protein-Coupled Receptor targeted drugs.Escient Pharmaceuticals is a privately-held biotechnology company focusing on the advancement of G Protein-Coupled Receptor targeted drugs.
Founded 2018San Diego, United States$120Mlast round Nov 2022 - 45
Elcelyx TherapeuticsElcelyx Therapeutics is developing nutrient sensing-based products for weight management and obesity-related metabolic disorders.Elcelyx Therapeutics is developing nutrient sensing-based products for weight management and obesity-related metabolic disorders.
Founded 2010San Diego, United States$117Mlast round Oct 2015 - 46
BiolinqBiolinq is a private healthcare technology company based in San Diego, California, founded in 2012.Biolinq is a private healthcare technology company based in San Diego, California, founded in 2012.
Founded 2012San Diego, United States$115Mlast round Mar 2025 - 47
Brain CorpBrain Corp is a San Diego-based company founded in 2009, specializing in autonomous technology and robotic AI software.Brain Corp is a San Diego-based company founded in 2009, specializing in autonomous technology and robotic AI software.
Founded 2009San Diego, United States$114Mlast round Jul 2016 - 48AccumetricsAccumetrics develops, manufactures, and markets the VerifyNow System, a suite of assays for the assessment of platelet function
Accumetrics develops, manufactures, and markets the VerifyNow System, a suite of assays for the assessment of platelet function
Founded 1996San Diego, United States$111Mlast round Aug 2013 - 49
RayTheraRayThera is dedicated to developing small molecule therapies specifically targeting unmet needs in immunology.RayThera is dedicated to developing small molecule therapies specifically targeting unmet needs in immunology.
Founded -San Diego, United States$110Mlast round Apr 2025 - 50
Human LongevityHuman Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.
Founded 2013San Diego, United States$110Mlast round Aug 2024
San Diego, United StatesEvery startup we hold in San Diego, ranked by the total it has raised in rounds we hold. Nobody pays to be on a list.
Who backed them?
Open any company for its rounds and investors, or search the investors who back startups in San Diego in the app, with filters, lists and exports.
More startup lists
See all
O
A
XStartups in the United States42,176 companies · $870B
SCN
FStartups in the United Kingdom8,355 companies · $79BO
D
TMStartups in San Francisco4,251 companies · $350B
W
K
PStartups in New York3,729 companies · $67BF
IL
PDStartups in London3,521 companies · $51B
MAM
TEStartups in France3,025 companies · $32B
C
H8
APStartups in Canada2,950 companies · $38B
BMore lists for San Diego
See allCTEBiotech startups in San Diego154 companies · $9.3BEVTHealthcare startups in San Diego81 companies · $6.5B
A
T
IAIT Services startups in San Diego39 companies · $396MSANBCAI startups in San Diego31 companies · $7.6BPTSTPBPharma startups in San Diego22 companies · $904MM
C
CBig Data & Analytics startups in San Diego19 companies · $381MLT
GInternet startups in San Diego10 companies · $126M