Top list · San Diego

AI startups in San Diego

31 AI startups in San Diego have raised money in rounds we track. These are the 31 that have raised the most, $7.6B between them.

$7.6Braised by these 31
31on our record in all
Shield AIraised the most
  1. 1Shield AIShield AI is an artificial intelligence company that aims to protect service members and civilians with intelligent systems.

    Shield AI is an artificial intelligence company that aims to protect service members and civilians with intelligent systems.

    Founded 2015San Diego, United States$7.0Blast round Nov 2026
  2. 2NetradyneNetradyne is a technology company based in San Diego, California, specializing in artificial intelligence, computer vision, and edge computing to enhance fleet

    Netradyne is a technology company based in San Diego, California, specializing in artificial intelligence, computer vision, and edge computing to enhance fleet

    Founded 2015San Diego, United States$127Mlast round Jan 2025
  3. 3Brain CorpBrain Corp is a San Diego-based company founded in 2009, specializing in autonomous technology and robotic AI software.

    Brain Corp is a San Diego-based company founded in 2009, specializing in autonomous technology and robotic AI software.

    Founded 2009San Diego, United States$114Mlast round Jul 2016
  4. 4KnuEdgeKnuEdge Inc.

    KnuEdge Inc.

    Founded 2005San Diego, United States$100Mlast round Jun 2016
  5. 5CordialCordial is a San Diego-based enterprise cross-channel marketing platform founded in 2014.

    Cordial is a San Diego-based enterprise cross-channel marketing platform founded in 2014.

    Founded 2014San Diego, United States$71Mlast round Jul 2022
  6. 6Liquid InstrumentsLiquid Instruments is a technology company founded in 2014 and based in San Diego, California.

    Liquid Instruments is a technology company founded in 2014 and based in San Diego, California.

    Founded 2014San Diego, United States$58Mlast round Apr 2026
  7. 7ClearNote HealthClearNote Health is a biotechnology company focused on enhancing early detection and monitoring of high-mortality cancers.

    ClearNote Health is a biotechnology company focused on enhancing early detection and monitoring of high-mortality cancers.

    Founded 2016San Diego, United States$52Mlast round May 2026
  8. 8SeasatsSeasats designs and manufactures small uncrewed surface vehicles (sUSVs) designed for monitoring, data collection, and defense applications.

    Seasats designs and manufactures small uncrewed surface vehicles (sUSVs) designed for monitoring, data collection, and defense applications.

    Founded 2020San Diego, United States$29Mlast round Feb 2026
  9. 9VIE TechnologiesVIE Technologies is a San Diego-based company founded in 2017 that specializes in AI-powered, non-invasive predictive maintenance solutions for critical industr

    VIE Technologies is a San Diego-based company founded in 2017 that specializes in AI-powered, non-invasive predictive maintenance solutions for critical industr

    Founded 2017San Diego, United States$15Mlast round Mar 2025
  10. 10Persephone BiosciencesPersephone Biosciences uses artificial intelligence to rapidly develop microbial based immunotherapies to enable a lifetime without cancer.

    Persephone Biosciences uses artificial intelligence to rapidly develop microbial based immunotherapies to enable a lifetime without cancer.

    Founded 2017San Diego, United States$15Mlast round Jul 2022
  11. 11Self InspectionSelf Inspection is an AI-powered technology company based in San Diego, California, founded in 2021.

    Self Inspection is an AI-powered technology company based in San Diego, California, founded in 2021.

    Founded 2021San Diego, United States$13Mlast round Jul 2026
  12. 12Ollie AIOllie is the world's first Family AI, built to lighten the mental load of parenthood.

    Ollie is the world's first Family AI, built to lighten the mental load of parenthood.

    Founded 2023San Diego, United States$7.5Mlast round Sept 2026
  13. 13HelloSkyHelloSky is an AI-powered Agentic Talent Intelligence Platform designed for executive search.

    HelloSky is an AI-powered Agentic Talent Intelligence Platform designed for executive search.

    Founded 2020San Diego, United States$5.5Mlast round Apr 2025
  14. 14XOKindXOKind is a San Diego-based AI startup founded in 2019, focused on creating AI agents that enhance human planning and decision-making.

    XOKind is a San Diego-based AI startup founded in 2019, focused on creating AI agents that enhance human planning and decision-making.

    Founded 2019San Diego, United States$5.3Mlast round Dec 2019
  15. 15Biosynch.aiPioneering the future of medicine through artificial intelligence and computational biology.

    Pioneering the future of medicine through artificial intelligence and computational biology.

    Founded -San Diego, United States$4.2Mlast round Apr 2025
  16. 16AcurionAcurion develops AI-driven diagnostic solutions that extract actionable genomic biomarker insights from standard pathology images.

    Acurion develops AI-driven diagnostic solutions that extract actionable genomic biomarker insights from standard pathology images.

    Founded -San Diego, United States$4.1Mlast round Apr 2026
  17. 17KantivThe pursuit intelligence platform for AEC marketing teams

    The pursuit intelligence platform for AEC marketing teams

    Founded 2022San Diego, United States$4.0Mlast round Jan 2025
  18. 18Sinopia BiosciencesSinopia Biosciences enables data-driven drug discovery by means of multi-omics data, machine learning, network analyses, and disease models.

    Sinopia Biosciences enables data-driven drug discovery by means of multi-omics data, machine learning, network analyses, and disease models.

    Founded 2014San Diego, United States$3.6Mlast round Jul 2026
  19. 19Nome BioNome is the Operating System for Personalized TherapiesTM, developing custom treatments for rare disease patients, families, and clinicians.

    Nome is the Operating System for Personalized TherapiesTM, developing custom treatments for rare disease patients, families, and clinicians.

    Founded -San Diego, United States$2.7Mlast round Oct 2025
  20. 20InformutaInformuta is a biotechnology and infectious disease intelligence company based in San Diego, founded in 2023.

    Informuta is a biotechnology and infectious disease intelligence company based in San Diego, founded in 2023.

    Founded 2023San Diego, United States$2.3Mlast round Sept 2026
  21. 21MirrorvaMirrorva builds real-time generative AI for video and interactive media.

    Mirrorva builds real-time generative AI for video and interactive media.

    Founded -San Diego, United States$2.0Mlast round Sept 2025
  22. 22lexonlegalLexonLegal provides AI-powered solutions for contract automation, compliance analysis, and litigation support.

    LexonLegal provides AI-powered solutions for contract automation, compliance analysis, and litigation support.

    Founded -San Diego, United States$1.2Mlast round Sept 2025
  23. 23NanomeNanome is a San Diego-based enterprise software company founded in 2015 by engineering students from the University of California, San Diego.

    Nanome is a San Diego-based enterprise software company founded in 2015 by engineering students from the University of California, San Diego.

    Founded 2015San Diego, United States$1.2Mlast round Jun 2024
  24. 24Dynam.AIDynam.AI is a San Diego-based software firm specializing in artificial intelligence and machine learning, founded in 2019.

    Dynam.AI is a San Diego-based software firm specializing in artificial intelligence and machine learning, founded in 2019.

    Founded 2019San Diego, United States$1.0Mlast round Jul 2022
  25. 25ReliablInclusive content moderation for community platforms.

    Inclusive content moderation for community platforms.

    Founded 2019San Diego, United States$370Klast round Jun 2024
  26. 26IGNITEIQIgniteIQ provides AI transformation and automation services for home services companies in HVAC, plumbing, electrical, and garage doors.

    IgniteIQ provides AI transformation and automation services for home services companies in HVAC, plumbing, electrical, and garage doors.

    Founded -San Diego, United States$350Klast round Sept 2026
  27. 27AthleteIQAthlete IQ connects athletes to the brands and events that celebrate them by helping brands maximize their sponsorship value and ROI at the event level.

    Athlete IQ connects athletes to the brands and events that celebrate them by helping brands maximize their sponsorship value and ROI at the event level.

    Founded 2014San Diego, United States$330Klast round Jan 2024
  28. 28FX1FX1 is a sports data and technology company that specializes in combat and live sports.

    FX1 is a sports data and technology company that specializes in combat and live sports.

    Founded 2019San Diego, United States$250Klast round Aug 2022
  29. 29Edtera, Inc.We are an educational and technology company serving the needs of students and educators.

    We are an educational and technology company serving the needs of students and educators.

    Founded 2018San Diego, United States$250Klast round Jan 2022
  30. 30MedlyticsAiMedlyticsAi is a healthcare AI company based in San Diego, founded in 2020.

    MedlyticsAi is a healthcare AI company based in San Diego, founded in 2020.

    Founded 2020San Diego, United States$250Klast round Oct 2021
  31. 31BWave AIAI-Powered Enterprise Voice Engine | Automate Your Customer Call Audio Without Human Recording

    AI-Powered Enterprise Voice Engine | Automate Your Customer Call Audio Without Human Recording

    Founded 2023San Diego, United States$190Klast round Jul 2025
Total fundinghow the list is ranked
15 November 2026updated nightly
Rounds we tracksource: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

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