Top list · United States
379 B2B startups in the United States have raised money in rounds we track. These are the 50 that have raised the most, $8.6B between them, with New York the most common home.
nCino provides a cloud banking platform that helps financial institutions modernize their operations and improve the customer experience.
Founded 2012Wilmington, United States$1.1Blast round Jan 2022Demand Media BPM LLP is a B2B marketing agency specializing in data-driven services and AI-powered intent marketing.
Founded 2020United States$588Mlast round Sept 2013Capchase is a fintech company that provides financial solutions to startups by allowing access to funds as they grow.
Founded 2020New York, United States$488Mlast round May 2026Behalf develops a digital platform that facilitates payments and accelerates cash flow by extending net terms and financing to businesses.
Founded 2011New York, United States$406Mlast round Jul 2021OWNER is a Dutch software company based in Emmen, specializing in business relationship management.
Founded 2018Emmen, United States$360Mlast round Aug 2026Bitsight is the global leader in cyber risk intelligence, helping teams make informed risk decisions with the industry’s most extensive external security data a
Founded 2011Boston, United States$350Mlast round Sept 2021Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries.
Founded 2013San Francisco, United States$332Mlast round Feb 2022The only digital tool your techs need on a jobsite, XOi is built for HVAC, Plumbing, Electrical, Construction, Kitchen Equipment, and more.
Founded 2013Nashville, United States$230Mlast round Feb 2025Axonic Insurance designs, distributes, issues, administers, services annuity and related product solutions for individuals and institutions.
Founded -New York, United States$210Mlast round Oct 2025Lusha IL sells gift boxes and iteams.
Founded 2020United States$205Mlast round Nov 2021Savvy Wealth is a technology-enabled wealth management firm.
Founded 2021New York, United States$188Mlast round Sept 2026Awardco is an employee recognition and total rewards platform that enhances workplace culture and drives employee loyalty through value-driven recognition programs.
Founded 2015Lindon, United States$165Mlast round May 2025LeafLink is a leading B2B technology platform and wholesale marketplace designed for the licensed cannabis industry.
Founded 2016New York, United States$156Mlast round Feb 2023Melio is a healthtech startup that uses cutting-edge blood test technology to help people maintain an active relationship with their health.
Founded 2019United States$154Mlast round Jan 2025We're building the operating system for independent doctors.
Founded -San Francisco, United States$135Mlast round Jun 2026DeFi Development Corp.
Founded 2023Boca Raton, United States$125Mlast round Aug 2025Sendoso is a leading B2B corporate gifting and direct mail platform, founded in 2016 and based in San Francisco, California.
Founded 2016San Francisco, United States$111Mlast round Sept 2021Daylit brings AI agents to Accounts Receivable.
Founded 2020Boston, United States$110Mlast round Sept 2025Justworks makes it easier to start, run, and grow a business.
Founded 2012New York, United States$110Mlast round Nov 2023Braavo Capital: integrated financing for mobile growth.
Founded 2015New York, United States$106Mlast round May 2024Quo helps people hire teams and accelerate software development.
Founded 2005United States$105Mlast round Sept 2025Settle was a Norwegian fintech company that operated Settle Group, positioning itself as Europe’s mobile payment network.
Founded 2010Oslo, United States$103Mlast round Oct 2026Growing small businesses through embedded financial services enabled on the very platforms on which SMBs sell & transact
Founded 2020San Francisco, United States$100Mlast round May 2026MentorcliQ is an employee mentoring software platform that helps upskill and retain employees.
Founded 2012Columbus, United States$86Mlast round Mar 2023Building developer experience tools of the future
Founded 2022San Francisco, United States$83Mlast round Sept 2026NuORDER is a cloud and mobile B2B eCommerce platform empowering brands and retailers to streamline their business operations.
Founded 2011Los Angeles, United States$73Mlast round Mar 2021Stedi is a technology company that operates as the world's first programmable healthcare clearinghouse.
Founded 2017New York, United States$70Mlast round Mar 2026Mural is an AI-powered visual workspace platform that enhances team collaboration by connecting strategy to execution in a shared digital environment.
Founded 2011San Francisco, United States$67Mlast round Oct 2026Amani Therapeutics is a biotechnology company based in New York, founded in 2025.
Founded 2025New York, United States$60Mlast round Oct 2026Precision Biologics is a Biotechnology company located in 5910 N Central Expy, Dallas, Texas, United States.
Founded 2012Dallas, United States$59Mlast round Oct 2015Skilljar is a customer training platform for enterprises to accelerate product adoption and improve customer retention.
Founded 2013Seattle, United States$57Mlast round Oct 2020Shepherd is a book discovery and exploration platform.
Founded 2020United States$56Mlast round Mar 2026Centro enables sales and support teams to Learn and react in Salesforce and Slack.
Founded 2020United States$53Mlast round May 2015Vow is a meat production company specializing in producing meat from animal cells.
Founded 2019United States$49Mlast round Aug 2025:Different is a modern, full-service property management company based in Australia.
Founded 2016Sydney, United States$48Mlast round Oct 2026NewtonX is a New York-based B2B market research company founded in 2016.
Founded 2017New York, United States$44Mlast round Dec 2021Reachdesk is a global corporate gifting and direct mail automation platform designed for B2B companies.
Founded 2018New York, United States$43Mlast round Sept 2021Convictional is a Supplier Enablement Platform and B2B trade enablement network founded in 2017, headquartered in Waterloo, Ontario, Canada.
Founded 2017Waterloo, United States$40Mlast round Feb 2022Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
Open any company for its rounds and investors, or search the investors who back b2B startups in the United States in the app, with filters, lists and exports.
CV
OB2B startups that raised in 2026118 companies · $3.3B in 2026
DM
C
LB2B startups founded in 202096 companies · $2.3B
SW
C
MB2B startups founded in 202184 companies · $1.1B
A
F
BB2B startups founded in 201979 companies · $1.7B
O
Z
HB2B startups founded in 201877 companies · $1.2B
E
J
SB2B startups founded in 202277 companies · $803M
S
T
BB2B startups in the United Kingdom76 companies · $1.5B
TB
L
SB2B startups in San Francisco63 companies · $1.2B
O
A
XStartups in the United States42,176 companies · $870B
GV
V
RPHealth startups in the United States7,411 companies · $71B
O
A
XAI startups in the United States5,656 companies · $718B
V
RP
DHHealthcare startups in the United States4,148 companies · $51B
S
P
IIT Services startups in the United States3,482 companies · $27B
D
CE
ADBig Data & Analytics startups in the United States2,107 companies · $132B
O
A
WAI startups in the United States that raised in 20261,648 companies · $431B in 2026
D
P