metaphore

Metaphore Biotechnologies is a biotechnology company based in Cambridge, Massachusetts, founded in 2021 by Flagship Pioneering.

The company specializes in designing novel therapeutics using biomimicry and machine learning. With a team of 11-50 employees, Metaphore operates privately and focuses on advancing drug discovery through its MIMiCTM platform. The MIMiCTM platform is a computational bioplatform that simulates molecular interactions found in nature. It isolates pharmacophores and optimizes them for drug discovery, allowing for targeted therapeutic development. Metaphore primarily addresses autoimmune disorders, metabolic diseases, and cancers, aiming to make challenging drug targets accessible and develop superior therapies. In May 2023, Metaphore received an initial investment of $50 million from Flagship Pioneering to support the MIMiCTM platform's advancement. The leadership team includes CEO Lovisa Afzelius, Chief Innovation Officer Daniel Acker, and Chief Scientific Officer Anabella Villalobos, among others.