CellFE

CellFE is a biotechnology and life sciences tools company based in Alameda, California.

Founded in 2018, the company focuses on a microfluidics-based cell engineering platform aimed at enhancing the development and manufacturing of advanced cell therapies. Led by CEO Alla Zamarayeva, Ph.D., CellFE is dedicated to making lifesaving cell therapies more accessible by addressing key challenges in therapeutic cell engineering, particularly in delivering gene-editing molecules into cells while maintaining cell viability. The company's primary product is a microfluidic device designed for non-viral, non-electroporative intracellular gene delivery. This platform efficiently transports hard-to-deliver molecules, such as large DNA sequences and mRNA, into cells, supporting rapid genome editing and streamlining manufacturing processes. CellFE's technology is particularly beneficial for T-cell therapies, hematopoietic stem cells, and iPSC-based therapies, offering significant advantages in scalability, automation, and cost reduction. The company operates a B2B model, collaborating with pharmaceutical and biotech companies, as well as translational medicine centers, to advance cell therapy research and development.