Sector portfolio · VC firm · United States
Two Sigma Ventures' AI portfolio
Two Sigma Ventures has backed 16 AI startups in rounds we track, $82B between them, shown by the stage each has reached. The best-funded is Xai.
Two Sigma Ventures's whole portfolioTwo Sigma Ventures's profile
Funding by segment
- Stage not reported$137M5
- Series B$538M4
- Pre-seed and seed$118M4
- Series C and later$81B3
Where they are based
- United States16$82B
United StatesFounded
4 without a founding year on record.
Total raised
- Under $1M0
- $1M to $10M0
- $10M to $50M8
- $50M to $250M5
- $250M to $1B2
- $1B and over1
Each dot is a startup: the year it was founded across, the total it has raised up (each line is ten times the one below). Pick a segment to pick it out.
12 of 16 startups shown; the rest have no founding year or amount on record.
- 1 to 2
- 3 to 7
- 8 to 24
- 25 to 99
- 100 and more
- United States16
Startups by country, 1 country in all.
Segment by segment
Stage not reported
5 startups · $137M raised
KasistoKasisto's enables financial institutions to service, engage, and acquire customers.United States$41M
Verge GenomicsVerge Genomics uses machine learning and human genomics to accelerate drug discovery.United States$36M
PryonPryon is an enterprise AI company that specializes in enhancing information retrieval through its core product, the Pryon Memory Layer.United States$25M
FormlogicFormlogic is an autonomous manufacturing company that uses machine learning and physics simulation to precision parts.United States$20M- SSpellSpell is the MLOps platform built to meet the unique challenges of operationalizing deep learning at scale.United States$15M
Series B
4 startups · $538M raised
- RRADARUnited States$269M
Terray TherapeuticsTerray Therapeutics is a biotechnology company that propels drug discovery into the information age.United States$145M
OsmoOsmo is an AI-powered olfactory intelligence company founded in 2022, specializing in digitizing smell.United States$73M
JiboJibo, Inc.United States$52M
Pre-seed and seed
4 startups · $118M raised
ArtemisArtemis operates an intelligence platform for indoor farms.United States$79M
HyperExplore HyperBot, HyperDesk, HyperClaw, and HyperBuild.United States$13M
ObjectiveObjective provides a browser extension that allows users to personalize priorities, adding filters, and contextualized data.United States$13M
NullifyNullify is an AI-first application security company that provides an autonomous AI workforce for product security.United States$13M
How this map is made. Every startup here works in AI and has raised money in a round we track that names Two Sigma Ventures as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.
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