Sector portfolio · Growth fund · United States

RTW Investments LLC's Biotech portfolio

RTW Investments LLC has backed 52 Biotech startups in rounds we track, $11B between them, shown by the stage each has reached. The best-funded is Oruka Therapeutics.

52startups backed
4stages
$11Braised between them
Stage not reportedbiggest stage

RTW Investments LLC's whole portfolioRTW Investments LLC's profile

Stage not reported

27

+3 more

Series B

12

Series C and later

8

Series A

5

Segment by segment

Stage not reported

27 startups · $5.7B raised

  1. Oruka TherapeuticsOruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases.United States$880M
  2. Spyre TherapeuticsSpyre Therapeutics is a biotechnology business that is developing a strong pipeline of antibody therapies.United States$678M
  3. Immunic TherapeuticsImmunic is a biopharmaceutical company that develops a pipeline of selective oral immunology therapies.United States$400M
  4. Century TherapeuticsCentury Therapeutics is a biotechnology company that develops cell therapies for hematological and solid tumor malignancies.United States$385M
  5. Belite BioBelite Bio is a clinical stage biopharmaceutical drug development company.United States$350M
  6. Rocket PharmaceuticalsRocket Pharmaceuticals is a biotech company that develops a pipeline of genetic therapies for rare childhood disorders.United States$340M
  7. Monte Rosa TherapeuticsMonte Rosa Therapeutics is a biotechnology company that develops cancer therapeutics that modulate protein degradation pathways.Switzerland$300M
  8. MoonLake ImmunotherapeuticsMoonLake Immunotherapeutics is a clinical-stage biopharmaceuticals company.Switzerland$275M

Series B

12 startups · $2.5B raised

  1. Kailera TherapeuticsKailera Therapeutics develops next-generation injectable and oral therapies for chronic weight management.United States$600M
  2. Windward BioWindward Bio is a clinical-stage biotechnology company with deep discovery, development, and commercialization expertise committedSwitzerland$365M
  3. Stoke TherapeuticsStoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.United States$255M
  4. Mirador TherapeuticsMirador Therapeutics is a clinical-stage precision medicine company based in San Diego, California.United States$250M
  5. Aktis OncologyAktis Oncology is a biotechnology company discovering and developing a novel class of targeted radiopharmaceuticals.United States$175M
  6. Kyverna TherapeuticsKyverna Therapeutics is pioneering a new class of therapies and cures for serious autoimmune diseases.United States$160M
  7. AIRNAAIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.United States$155M
  8. Tenaya TherapeuticsTenaya Therapeutics is a developer of novel therapies designed to offer treatment for heart disease.United States$152M

Series C and later

8 startups · $2.1B raised

  1. Encoded TherapeuticsEncoded Therapeutics is a Harnessing the regulatory genome to create next-generation molecular therapies.United States$379M
  2. ZLZai LabChina$310M
  3. Beta BionicsBeta Bionics is a biotechnology company that develops an integrated bionic pancreas system called the iLet.United States$296M
  4. CORXEL PharmaceuticalsCORXEL Pharmaceuticals is a clinical-stage biopharmaceutical company founded in 2019, previously known as JiXing Pharmaceuticals.United States$287M
  5. Science 37Science 37 is a clinical research company that facilitates universal participation in clinical trials for patients and providers.United States$236M
  6. NBNuance BiotechNuance Biotech is a pharmaceutical company Based In China.China$201M
  7. Lycia TherapeuticsLycia Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California.United States$182M
  8. Nuance PharmaNuance Pharma is a specialty biopharmaceutical company based in Shanghai, founded in 2014 by Mark Lotter.China$181M

Series A

5 startups · $583M raised

  1. CPCinCor PharmaCinCor is a clinical-stage biopharmaceutical company that develops treatments for cardiovascular diseases.United States$275M
  2. Ottimo PharmaOttimo Pharma is a private, clinical-stage biotechnology company based in Sandwich, Kent, United Kingdom.United Kingdom$140M
  3. Alesta TherapeuticsAlesta Therapeutics focused on translating novel targets in the chronic stress response pathways into new therapeutic.Netherlands$67M
  4. Amani TherapeuticsAmani Therapeutics is a biotechnology company based in New York, founded in 2025.United States$60M
  5. RenovacorNo mercado desde 2009, a Renovacor Tintas se diferencia pela fabricação de tintas e revestimentos acrílicos de qualidade que contaUnited States$41M

How this map is made. Every startup here works in Biotech and has raised money in a round we track that names RTW Investments LLC as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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