Who invested in Spyre Therapeutics

2 rounds we have observed, with the 4 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

Biotech

Raised 7 months ago

Funding summaryUpdated 26 Oct 2026

$678Mraised across 2 rounds since 2025, from 2 sources

$275MRound$403MRound

Latest round: Round, $403MApr 2026
Step-upi: 1.5×
Investors: 4

See who backed them

The funding story

Each circle is a round, placed by date and sized by amount. The line above is the running total.

2026

$275MRound$403MRound

First round: Round, $275M
Biggest round: $403M
Between rounds: 6 months

The rounds

Apr 2026
Round$403M4 returning
Source recorded
Oct 2025
Round$275M4 new
Source recorded

Founders and team

From Spyre Therapeutics's own website and the SEC filings it signed: 6 on the team.

Cameron TurtleChief Executive Officer
Brian ConnollyChief Technical Officer
Kate Tansey ChevlenChief Commercial Officer
Sheldon SloanChief Medical Officer
Heidy King-JonesChief Legal Officer and Corporate Secretary
Scott BurrowsChief Financial Officer

On the board, as filediAlison J. LawtonJeffrey W. AlbersLaurie J. StelzerMichael J. HendersonPeter J. HarwinRussell J. CoxTomas J. Kiselak

Who was in which round

The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.

Round2025Round2026

Perceptive Advisors

Cormorant Asset Management

RTW Investments LLCAdage Capital Management

Everyone who backed them

Perceptive AdvisorsAsset manager2rounds

Cormorant Asset ManagementPrivate equity2rounds

RTW Investments LLCGrowth equity2rounds

Adage Capital ManagementAsset manager2rounds

Missing a round, or an investor who was in one? Tell us.

Quick answers about Spyre Therapeutics

Who invested in Spyre Therapeutics?

Spyre Therapeutics's investors include Perceptive Advisors, Cormorant Asset Management, RTW Investments LLC and Adage Capital Management.

How much has Spyre Therapeutics raised?

Spyre Therapeutics has raised $678M across 2 rounds since 2025.

When did Spyre Therapeutics last raise?

Spyre Therapeutics's most recent round was an Undisclosed round of $403M in Apr 2026.

What was Spyre Therapeutics's biggest round?

Its most recent round, $403M in Apr 2026, is also its largest on record.

Who backed Spyre Therapeutics first?

Spyre Therapeutics's first round on record, in Oct 2025, was backed by Perceptive Advisors, Cormorant Asset Management and RTW Investments LLC and 1 others.