Investments abroad · Private equity · United Kingdom

Janus Henderson Investors' investments in the United States

Janus Henderson Investors, based in the United Kingdom, has backed 111 startups in the United States in rounds we track, $23B between them, grouped by their main sector.

111startups backed
6sectors
$23Braised between them
Biotechbiggest sector

Janus Henderson Investors's whole portfolioJanus Henderson Investors's profile

Biotech

73

+49 more

Pharma

29

+5 more

AI

3

Logistics

2

Healthtech

2

Consumer Goods

2

Segment by segment

Biotech

73 startups · $17B raised

  1. Tango TherapeuticsTango Therapeutics is a biotechnology company that is developing next generation cancer therapies.United States$852M
  2. Definium TherapeuticsDefinium Therapeutics provides psychedelic-inspired medicines and therapies for substance abuse disorders and other mental illnesses.United States$805M
  3. Kymera TherapeuticsKymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.United States$799M
  4. Avidity BiosciencesSynapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.United States$790M
  5. Structure TherapeuticsStructure Therapeutics specializes in the discovery and development of drugs against a type of targets called GPCR.United States$748M
  6. Tyra BiosciencesTyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.United States$600M
  7. Kailera TherapeuticsKailera Therapeutics develops next-generation injectable and oral therapies for chronic weight management.United States$600M
  8. Phathom PharmaceuticalsPhathom Pharmaceuticals is a biopharmaceutical company.United States$530M

Pharma

29 startups · $5.2B raised

  1. Dianthus TherapeuticsDianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach.United States$719M
  2. VaxcyteVaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.United States$633M
  3. Korsana BiosciencesKorsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s.United States$530M
  4. Parabilis MedicinesParabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines.United States$380M
  5. Maze TherapeuticsMaze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines.United States$300M
  6. Compass TherapeuticsCompass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.United States$257M
  7. MetseraMetsera operates as a clinical-stage biopharmaceutical company.United States$215M
  8. Edgewise TherapeuticsEdgewise Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization.United States$200M

AI

3 startups · $673M raised

  1. HeartFlowHeartFlow is a medical technology company that provides various methods of diagnosis and treatment of cardiovascular disease.United States$586M
  2. Arbor BiotechnologiesArbor Biotechnologies is a gene editing company based in Cambridge, Massachusetts, dedicated to developing genomic medicines for aUnited States$74M
  3. TareTare is an AI-powered email marketing solution that makes data-driven automation easy for modern e-commerce brands.United States$13M

Logistics

2 startups · $27M raised

  1. LoadsmartLoadsmart is a logistics technology company based in Chicago, founded in 2014.United States$25M
  2. Xos TrucksXos Trucks specializes in the field of manufacturing fully electric commercial vehicles.United States$2.4M

Healthtech

2 startups · $195M raised

  1. IntelyCareIntelyCare is an AI-based healthcare workforce management platform that connects nursing professionals with healthcare facilities United States$126M
  2. Magnolia Medical TechnologiesMagnolia Medical Technologies is a Seattle-based healthcare company focused on improving diagnostic accuracy for sepsis detection United States$69M

Consumer Goods

2 startups · $254M raised

  1. NeuroNeuro is a functional gum and mint company creating smarter ways to help energize, calm, and focus the mind.United States$200M
  2. OBOwlet Baby CareOwlet Baby Care offers a health monitor that allows parents to view their child's vital signs in real-time.United States$54M

How this map is made. Every startup here has raised money in a round we track that names Janus Henderson Investors as an investor and is based in United States. Each sits under its main sector, read from its rounds, and each shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

More portfolio maps

All portfolios
Portfolio mapJanus Henderson Investors portfolio map128 startups · $28BSector portfolioJanus Henderson Investors' Biotech portfolio89 startups · $21BCo-investorsWho invests with Janus Henderson Investors80 co-investorsSector portfolioJanus Henderson Investors' Pharma portfolio35 startups · $6.2BInvestments abroadDST Global's investments in the United States44 startups · $240BInvestments abroad3i Group's investments in the United States24 startups · $1.8B

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