Sector portfolio · Private equity · United Kingdom

Janus Henderson Investors' Biotech portfolio

Janus Henderson Investors has backed 89 Biotech startups in rounds we track, $21B between them, shown by the stage each has reached. The best-funded is Tango Therapeutics.

89startups backed
4stages
$21Braised between them
Stage not reportedbiggest stage

Janus Henderson Investors's whole portfolioJanus Henderson Investors's profile

Stage not reported

41

+17 more

Series C and later

21

Series B

17

Series A

10

Segment by segment

Stage not reported

41 startups · $8.8B raised

  1. Definium TherapeuticsDefinium Therapeutics provides psychedelic-inspired medicines and therapies for substance abuse disorders and other mental illnesses.United States$805M
  2. Structure TherapeuticsStructure Therapeutics specializes in the discovery and development of drugs against a type of targets called GPCR.United States$748M
  3. Tyra BiosciencesTyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.United States$600M
  4. Phathom PharmaceuticalsPhathom Pharmaceuticals is a biopharmaceutical company.United States$530M
  5. NuvalentNuvalent is a biopharmaceutical company that develops targeted therapies for cancer by designing small-molecule medicines.United States$500M
  6. Enliven TherapeuticsEnliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives.United States$460M
  7. New Amsterdam PharmaNew Amsterdam is a clinical-stage company focused on the research and development of transformative therapies for cardio-metabolic diseases.Netherlands$453M
  8. Immunic TherapeuticsImmunic is a biopharmaceutical company that develops a pipeline of selective oral immunology therapies.United States$400M

Series C and later

21 startups · $5.4B raised

  1. Kymera TherapeuticsKymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.United States$799M
  2. Avidity BiosciencesSynapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.United States$790M
  3. TubulisTubulis is a chemotherapeutic medication developer specializing in cancer and chronic disease treatment.Germany$401M
  4. Encoded TherapeuticsEncoded Therapeutics is a Harnessing the regulatory genome to create next-generation molecular therapies.United States$379M
  5. GalectoGalecto is a clinical stage biotechnology company focused on the development of novel treatments for fibrosis and cancer.Denmark$365M
  6. Solid BiosciencesSolid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy.United States$333M
  7. Star TherapeuticsStar Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018.United States$325M
  8. Obsidian TherapeuticsObsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.United States$210M

Series B

17 startups · $4.4B raised

  1. BBioNTechGermany$687M
  2. Kailera TherapeuticsKailera Therapeutics develops next-generation injectable and oral therapies for chronic weight management.United States$600M
  3. Akero TherapeuticsAkero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state.United States$502M
  4. Artiva BiotherapeuticsArtiva Biotherapeutics is a biotech company focused on developing and commercializing allogeneic natural killer (NK) cell therapies.United States$420M
  5. Windward BioWindward Bio is a clinical-stage biotechnology company with deep discovery, development, and commercialization expertise committedSwitzerland$365M
  6. Quell TherapeuticsQuell Therapeutics is a cell therapy companyUnited Kingdom$274M
  7. Stoke TherapeuticsStoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.United States$255M
  8. Gracell BiotechnologiesGracell Biotechnologies is a developer of cancer immune therapy designed to treat cancer.China$185M

Series A

10 startups · $2.1B raised

  1. Tango TherapeuticsTango Therapeutics is a biotechnology company that is developing next generation cancer therapies.United States$852M
  2. Disc MedicineDisc Medicine is a biopharmaceutical company that develops therapies for hematologic diseases and rare blood disorders.United States$275M
  3. Verve TherapeuticsVerve Therapeutics is a genetic medicine firm that is developing treatments for cardiovascular disease.United States$202M
  4. NeurogeneNeurogene is a developer of genetic medicines intended to improve patient outcomes for neurological disorders.United States$194M
  5. Ottimo PharmaOttimo Pharma is a private, clinical-stage biotechnology company based in Sandwich, Kent, United Kingdom.United Kingdom$140M
  6. Caribou BiosciencesCaribou Biosciences is a biotechnology company that develops CRISPR technologies and allogenic cell therapies for oncology.United States$139M
  7. Ambros TherapeuticsAmbros Therapeutics is a clinical-stage biotechnology company.United States$125M
  8. Think BioscienceThink Bioscience is a synthetic biology company located in Boulder, Colorado.United States$55M

How this map is made. Every startup here works in Biotech and has raised money in a round we track that names Janus Henderson Investors as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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