Portfolio map · Venture debt · United States

Hercules Capital portfolio map

46 startups Hercules Capital has backed in rounds we track, since 2005, grouped by their main sector. Together they have raised $7.7B. The biggest sector is Biotech, with 21 companies.

46startups backed
7sectors
$7.7Braised between them
Biotechbiggest sector

Hercules Capital's profile

Biotech

21

AI

6

Pharma

5

Healthtech

4

Internet

4

Software

3

Automotive & EVs

3

Segment by segment

Biotech

21 startups · $3.5B raised

  1. Dyne TherapeuticsDyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.United States$828M
  2. Phathom PharmaceuticalsPhathom Pharmaceuticals is a biopharmaceutical company.United States$530M
  3. 4D Molecular Therapeutics4D Molecular Therapeutics designs, develops, and commercializes transformative gene therapeutic products for unmet medical conditions.United States$307M
  4. MoonLake ImmunotherapeuticsMoonLake Immunotherapeutics is a clinical-stage biopharmaceuticals company.Switzerland$275M
  5. X4 PharmaceuticalsX4 Pharmaceuticals is a clinical-stage oncology company developing oral small molecule CXCR4 antagonists for the treatment.United States$193M
  6. MedroboticsMedrobotics is a medical robotics company developing and commercializing the Flex Robotic System.United States$176M
  7. 908 Devices908devices manufactures battery-operated, hand-held chemical detection tools used in mass spectrometry.United States$168M
  8. Replimune GroupReplimune Group develop the next generation of ‘oncolytic immunotherapies’ for the treatment of cancer.United States$140M

AI

6 startups · $1.3B raised

  1. PPerkSouth Africa$500M
  2. IntercomIntercom is the only helpdesk with a natively integrated AI Agent, Fin, meaning every customer conversation improves the next one,Ireland$250M
  3. BehavoxBehavox is a London-based AI company founded in 2014, specializing in compliance and risk management for financial services and reUnited Kingdom$245M
  4. UdacityUdacity develops an online learning platform offering programs in artificial intelligence, machine learning, and robotics sector.United States$165M
  5. UnifyMortgage business growth in one place.United States$98M
  6. Better TherapeuticsBetter Therapeutics develops prescription software for treating cardiometabolic diseases.United States$250K

Pharma

5 startups · $1.2B raised

  1. Axsome TherapeuticsAxsome Therapeutics is a biopharmaceutical company that develops therapies for the management and treatment of neurological disorders.United States$577M
  2. Madrigal PharmaceuticalsMadrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases.United States$350M
  3. Kura OncologyKura Oncology, a biopharmaceutical company, advances a pipeline of precision medicines for the treatment of solid tumors and blood cancers.United States$210M
  4. Verastem OncologyVerastem is a biopharmaceutical company developing new medicines to improve the lives of patients with RAS/MAPK pathway-driven cancers.United States$90M
  5. PolyMedixPolyMedix develops small molecule compounds for the treatment of acute cardiovascular disorders and infectious diseases.United States$14M

Healthtech

4 startups · $1.2B raised

  1. Main Street HealthMain Street Health is the largest provider of value-based care dedicated to rural America.United States$347M
  2. Oak Street HealthOak Street Health is a network of primary care centers for adults on Medicare.United States$340M
  3. TricidaTricida operates in the healthcare industry focusing on pharmaceutical business.United States$327M
  4. SukiSuki is an AI-powered ambient clinical intelligence platform and voice assistant tailored for healthcare professionals.United States$175M

Internet

4 startups · $125M raised

  1. RazorGatorRazorGator is an online ticket reselling platform for sports, theater and concert tickets, and vacation packages for sporting events.United States$59M
  2. hi5Hi5 is a social networking site that allows its users to create, upload, and share content with other members.United States$52M
  3. KadoinkGather people instantly by AI txt, video, or ringing phones Tell Kadoink Who You Need.United States$9.5M
  4. just.me Inc2011-2013, built a mobile social app called just.me.United States$4.3M

Software

3 startups · $171M raised

  1. WildTangentWildTangent is a game network for PC manufacturing.United States$101M
  2. AtrentaAtrenta's SpyGlass Predictive Analyzer® significantly improves design efficiency for the world's leading semiconductor and consumeUnited States$46M
  3. BlurbAbout Blurb® Blurb is a bookmaking platform and creative community specializing in photo books and the tools to self-publish them.United States$24M

Automotive & EVs

3 startups · $156M raised

  1. CarwowCarwow is Europe's leading online marketplace for buying new cars and selling used ones.United Kingdom$131M
  2. 3Gtms3GTMS develops software that simplifies complex transportation management for shippers, brokers and 3PLs.United States$15M
  3. RumbleONRumbleON provides an e-commerce platform that facilitates to sell, buy, trade pre-owned recreation vehicles.United States$10M

How this map is made. Every startup here has raised money in a round we track that names Hercules Capital as an investor, the first in 2005. Each sits under its main sector, read from its rounds, and each shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

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