Sector portfolio · VC firm · United States
Flagship Pioneering's Biotech portfolio
Flagship Pioneering has backed 25 Biotech startups in rounds we track, $3.1B between them, shown by the stage each has reached. The best-funded is Denali Therapeutics.
25startups backed
4stages
$3.1Braised between them
Stage not reportedbiggest stage
Flagship Pioneering's whole portfolioFlagship Pioneering's profile
Funding by segment
- Stage not reported$688M8
- Series A$335M6
- Series C and later$683M6
- Series B$1.4B5
Where they are based
- United States24$2.9B
United StatesFounded
3Earlier
112
213
14
515
116
417
118
119
220
221
22
23
24
25
26
3 without a founding year on record.
Total raised
- Under $1M0
- $1M to $10M1
- $10M to $50M5
- $50M to $250M16
- $250M to $1B3
- $1B and over0
Each dot is a startup: the year it was founded across, the total it has raised up (each line is ten times the one below). Pick a segment to pick it out.
22 of 25 startups shown; the rest have no founding year or amount on record.
- 1 to 2
- 3 to 7
- 8 to 24
- 25 to 99
- 100 and more
- United States24
Startups by country, 1 country in all.
Segment by segment
Stage not reported
8 startups · $688M raised
Rubius TherapeuticsRubius has developed the technology to grow, genetically engineer and mature long-circulating Red-Cell Therapeutics.United States$300M
Kaleido BioSciencesKaleido BioSciences is a company working to design and analyze the microbiome system and provide adaptive solutions.United States$161M
CygnalCygnal is a polling & survey research firm serving center-right consultant, caucus, committee, political & advocacy organizations.United States$65M
Metaphore BiotechnologiesMetaphore Biotechnologies is a biotechnology company based in Cambridge, Massachusetts, founded in 2021 by Flagship Pioneering.United States$50M
Omega TherapeuticsOmega Therapeutics offers a proprietary epigenomic programming platform.United States$40M
Tarveda TherapeuticsTarveda Therapeutics is a developer of miniature drug conjugates designed for the treatment of patients with a wide range of solid tumors.United States$36M
AxcellaAxcella is a biotechnology company that treats diseases using endogenous metabolic modulators.United States$34M
Apriori BioApriori Bio offers a platform for creating variant-resilient vaccines and provides real-time insights to prepare for future outbreaks.United States$1.1M
Series A
6 startups · $335M raised
Codiak BiosciencesCodiak is a clinical-stage biopharmaceutical company focused on pioneering the development of exosome-based therapeutics.United States$100M
Vesalius TherapeuticsVesalius Therapeutics is a biopharmaceutical company dedicated to redefining the understanding and treatment of diseases that accoUnited States$75M
ProFound TherapeuticsProFound Therapeutics is creating profound impacts on the understanding of biology and disease and the ability to create therapeutics.United States$75M
EtiomeEtiome is a biotechnology company based in Cambridge, Massachusetts, founded in 2021 by Flagship Pioneering.United States$50M
TorqueTorque is an open-source framework provider that specializes in self-configuring cloud systems for development operations (DevOps).United States$25M- BBoragenUnited States$10M
Series C and later
6 startups · $683M raised
KSQ TherapeuticsKSQ Therapeutics is using CRISPR technology within a powerful drug discovery engine to enable high-confidence drug development.United States$156M
Senda BiosciencesSenda Biosciences is a therapeutics platform company leveraging unprecedented insights into the molecular connections between humans.United States$123M
CellarityCellarity is a biotechnology therapeutics company based in Somerville, Massachusetts, founded in 2017 by Flagship Pioneering.United States$121M
VisterraVisterra researches on and develops therapeutic and diagnostic products for the treatment of infectious diseases.United States$120M
Ring TherapeuticsRing Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2017 by Flagship Pioneering.United States$87M- CCodiakUnited States$77M
Series B
5 startups · $1.4B raised
Denali TherapeuticsDenali Therapeutics is dedicated to defeating neurodegenerative diseases to deliver safe and effective medicines to patients and families.United States$547M
LarondeLaronde develops an eRNA-based therapeutic platform that is capable of indicating diverse proteins inside the body.United States$440M
Repertoire Immune MedicinesRepertoire Immune Medicines is a clinical stage biotechnology company.-$189M
AlltrnaAlltrna is a biotechnology company based in Cambridge, Massachusetts, founded in 2018.United States$109M
Evelo BiosciencesEvelo Biosciences is a biotechnology company that develops oral biologics for small intestinal axis with systemic therapeutic effects.United States$76M
How this map is made. Every startup here works in Biotech and has raised money in a round we track that names Flagship Pioneering as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.
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