Sector portfolio · VC firm · United States

ARCH Venture Partners' Biotech portfolio

ARCH Venture Partners has backed 104 Biotech startups in rounds we track, $15B between them, shown by the stage each has reached. The best-funded is Grail.

104startups backed
5stages
$15Braised between them
Series Abiggest stage

ARCH Venture Partners's whole portfolioARCH Venture Partners's profile

Segment by segment

Series A

30 startups · $2.9B raised

  1. ErascaErasca is a developer of oncology drugs intended to provide precision oncology options.United States$739M
  2. Dispatch BioDispatch Bio is a biotechnology company founded in 2022, focused on developing a universal treatment for solid tumors.United States$216M
  3. Tome BiosciencesTome Biosciences is a biotechnology company based in Watertown, MA, focused on advancing programmable genomic integration (PGI) toUnited States$213M
  4. Verve TherapeuticsVerve Therapeutics is a genetic medicine firm that is developing treatments for cardiovascular disease.United States$202M
  5. Treeline BiosciencesTreeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.United States$200M
  6. Tenvie TherapeuticsTenvie Therapeutics, Inc.United States$200M
  7. Bitterroot BioBitterroot Bio, Inc.United States$145M
  8. Paratus SciencesParatus Sciences is a biotechnology startup founded in 2021, based in New York, NY, with a subsidiary in Singapore.United States$100M

Series B

29 startups · $5.9B raised

  1. GGrailUnited States$1.6B
  2. Gossamer BioGossamer Bio is a biopharmaceutical company focused on the discovery and development of novel and differentiated therapeutic products.United States$567M
  3. Denali TherapeuticsDenali Therapeutics is dedicated to defeating neurodegenerative diseases to deliver safe and effective medicines to patients and families.United States$547M
  4. Beam TherapeuticsBeam Therapeutics is a biotechnology company developing precision genetic medicines through the use of base editing technology.United States$322M
  5. Mirador TherapeuticsMirador Therapeutics is a clinical-stage precision medicine company based in San Diego, California.United States$250M
  6. CTCity TherapeuticsUnited States$235M
  7. CREATE MedicinesCREATE Medicines is a clinical-stage biotechnology company based in Cambridge, Massachusetts.United States$195M
  8. Hua MedicineHua Medicine is a clinical-stage, innovative drug development company in China.China$192M

Stage not reported

22 startups · $2.4B raised

  1. EQRxEQRx is a biotechnology company that focuses on re-engineering the process of drug discovery to make them affordable.United States$1.2B
  2. Rapport TherapeuticsRapport Therapeutics is a clinical-stage biotechnology company that discovers and develops precision medicines for neurological disorders.United States$250M
  3. bluebird biobluebird bio is pursuing curative gene therapies to give patients and their families more bluebird days.United States$151M
  4. Vir BiotechnologyVir Biotechnology is an immunology company that develops products to treat and prevent infectious diseases and other serious conditions.United States$150M
  5. BIND TherapeuticsBIND Therapeutics is a biotechnology company incorporated in 2006; Pfizer acquired substantially all of its assets in 2016.United States$138M
  6. Lyell ImmunopharmaLyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer.United States$100M
  7. NNeurogesXNeurogesX develops and commercializes therapies for chronic peripheral neuropathic pain.United States$92M
  8. Sana BiotechnologySana Biotechnology is a developer of engineered cells intended to be used as medicine for patients.United States$69M

Series C and later

21 startups · $3.6B raised

  1. ArsenalBioArsenalBio is a programmable cell therapy company that offers advanced CAR T-cell therapies for solid tumors.United States$410M
  2. Encoded TherapeuticsEncoded Therapeutics is a Harnessing the regulatory genome to create next-generation molecular therapies.United States$379M
  3. EeGenesisUnited States$329M
  4. bit.biobit.bio is a synthetic biology and cell programming company based in Cambridge, United Kingdom.United Kingdom$264M
  5. LifeMine TherapeuticsLifeMine Therapeutics combines genomics with AI and synthetic biology to discover and develop a pipeline of novel medicines.United States$230M
  6. Dewpoint TherapeuticsDewpoint Therapeutics is a biotech company developing a drug platform that targets biomolecular condensates.United States$196M
  7. Vividion TherapeuticsWe are bringing more disease-causing targets within the reach of small molecule therapeutics to transform care for patients with dUnited States$185M
  8. MetacrineMetacrine is a clinical-stage bio pharmaceutical company focused on building an innovative pipeline of best-in-class drugs.United States$173M

Pre-seed and seed

2 startups · $18M raised

  1. UBUltraDx BioUltraDx Bio is a biotechnology company that specializes in single-molecule digital high-sensitivity protein detection technology.China$14M
  2. Nebula GenomicsNebula Genomics is a personal genomics company based in San Francisco, California, founded in 2016 by Dr.United States$4.3M

How this map is made. Every startup here works in Biotech and has raised money in a round we track that names ARCH Venture Partners as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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