The week's news · new episode 23 Oct 2026

All-In

Hosted by Chamath Palihapitiya, Jason Calacanis, David Sacks and David Friedberg

Four investors on the week in technology, markets and politics.

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440episodes
52investors heard as guests
1h 17man average episode
124 in the last 12 months

The regulars

Investors named as guests in the most episode titles on All-In.

Every episode 440 · page 1 of 15

  1. 440
    AI Cyber Panic, Ken Griffin's Bubble Warning, The Fall of France?23 Oct 2026 · 1h 43mNikesh Arora
    About this episode

    (0:00) Bestie intros! (0:11) Ken Griffin's AI bubble warning (8:19) Palo Alto Networks CEO Nikesh Arora joins (14:24) AI Cyber panic: PHP exploits and the tumultuous year ahead (44:17) France on the brink: Riots, immigration referendum, debt crisis (1:31:49) Trump's second half strategy, Press Secretary J-Cal?…

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  2. 439
    Arvind Krishna & Nikesh Arora: Quantum Threat, Open vs Frontier AI, AI Cyber Warfare & SaaS Collapse21 Oct 2026 · 40 minNikesh Arora
    About this episode

    (0:00) Arvind Krishna & Nikesh Arora talk about Quantum Computing's Threat to Encryption (9:07) Open Weight vs. Frontier AI Models (18:07) AI and Cyber Warfare (21:14) AI Regulation and the Global AI Arms Race (30:32) Vertical Integration and Software Consolidation Follow Nikesh: https://x.com/nikesharora…

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  3. 438
    Dylan Field: Is AI Replacing Designers?, Design is the New Code & Democratizing Creativity19 Oct 2026 · 41 minDylan Field
    About this episode

    (0:00) Dylan Field joins the show: Figma's origin story and mission (3:16) Adobe's $20B deal blocked: inside the antitrust fight (12:29) Is AI killing SaaS? Frontier Companies vs. Figma, the "SaaS apocalypse" (18:52) Creativity in the AI era: why taste and boldness win (36:02) Human agency, AI's promise, and what…

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  4. 437
    CoreWeave Crash, AI Trade Cracks, Anthropic IPO Red Flags, Bill Gates Doomer17 Oct 2026 · 1h 34mBill GatesBen Horowitz
    About this episode

    (0:00) Ben Horowitz fills in for Friedberg! (2:18) CoreWeave's debt selloff: did the AI bubble just pop? (31:14) AI's deflationary impact: decompiled software (45:44) Anthropic's investor day gets mixed reactions (1:03:45) Psyop Corner: Anthropic warns about self-replicating models on IoT devices (1:22:19)…

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  5. 436
    Elizabeth Holmes' Husband Billy Evans: The Trial, Prison & Nathan Fielder's Documentary15 Oct 2026 · 42 min
    About this episode

    (0:00) Billy Evans joins Friedberg (3:38) How they met, Elizabeth the person vs the headlines, indictment (11:02) Life on trial, having a child, where she went wrong in fundraising (19:28) Understanding the verdict, sentencing, and the mistake of staying silent (26:09) Elizabeth calls from prison, her life in jail…

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  6. 435
    Martin Shkreli: Big Pharma's Blind Spot, Betting Against Quantum & What Prison Taught Him12 Oct 2026 · 25 minMartin Shkreli
    About this episode

    (0:00) Martin Shkreli joins the Besties! (0:55) Why quantum computing is a one-trick business and why he's betting against it (7:42) The drugs big pharma sells too cheap and his journey from hedge fund trader to pharma (11:37) AI, drug discovery, and who actually wins (21:32) Brilliance and rule-breaking, the…

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  7. 434
    Is Claude Conscious? Pope Rejects, Model Welfare Movement, OpenAI's Math Backlash, France Riots10 Oct 2026 · 1h 33m
    About this episode

    (0:00) Bestie intros! (2:53) Anthropic believes Claude might be conscious: a new religion? Lobbying the Pope, alignment risks, model welfare (38:28) OpenAI's math breakthroughs and community backlash (1:02:03) Riots in France, Friedberg's socialism metric, bond market (1:21:41) Grok Bot goes headless, OpenAI…

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  8. 433
    Trump's Super Intelligence Summit, AI Safety Accord, GDP Beats, Midterm Predictions2 Oct 2026 · 1h 22m
    About this episode

    (0:00) Bestie intros! (2:01) Trump's Super Intelligence Summit: Behind the scenes and how the accord was created and signed (17:57) Cybersecurity arms race, data center national security, America.gov, coordinated doomer messaging (45:22) Recent economic data: GDP, jobs, diesel, inflation, rates, manufacturing,…

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  9. 432
    Jake Paul & The Chainsmokers: Turning Fame into Funds, Jake Enters Politics? & Venture Bubble Signs30 Sept 2026 · 53 minJake PaulAlex PallDrew Taggart
    About this episode

    (0:00) Jake Paul joins the Chamath! (6:41) Turning an audience into businesses, the boxing playbook & coming for the UFC (11:54) Attention as capital, investing without the celebrity label & why politics is next (20:46) Drew Taggart & Alex Pall join the Besties! (30:35) From artists to investors: picking deals,…

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  10. 431
    Daniel Ek: Life After Spotify, Broken Healthcare Incentives, Catching Disease Early & AI's Potential28 Sept 2026 · 51 minDaniel Ek
    About this episode

    (0:00) Daniel Ek joins the Besties! (1:14) Starting Spotify: Beating piracy and betting his own money on the record labels (6:10) Neko Health: The Spotify playbook for healthcare, the $499 body scan, and why US healthcare waits until you're sick (36:04) AI: Tech's failure to sell the upside, open vs. closed models,…

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  11. 430
    Anthropic IPO at Risk, Meta's Muse Pop, Token Prices Fall, Open Source Gains Share, Alignment Fails26 Sept 2026 · 1h 34m
    About this episode

    (0:00) Bestie Intros: Favorite All-In Summit moments (3:54) Reacting to AI chaos: Liability, competition, and rebranding frontier "labs" (20:03) Open Source performance and cost: What this means for frontier companies (29:22) Anthropic and OpenAI postpone IPOs: liquidity risk and open source pressure (53:11)…

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  12. 429
    Luca Ferrari, Bending Spoons CEO: The $40K Origin Story, Buying Product-Market Fit & Why Private Equity Can't Compete23 Sept 2026 · 26 minLuca Ferrari
    About this episode

    (0:00) Luca Ferrari joins the Besties! (1:56) Crashing an AI startup, the $40,000 restart & buying product market fit (4:59) The in-house tech stack, shrinking the teams & the 10 out of 10 standard (9:55) Debt as an accelerant, what happens if rates rise & who else is bidding (14:58) Inside the deal desk: what…

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  13. 428
    Steve Hilton & Spencer Pratt: Fixing California, Cheaper Gas, Ballot Fraud & CA Republicans23 Sept 2026 · 56 min
    About this episode

    (0:00) Steve Hilton joins the Besties! (3:53) How one-party rule broke the state, regulatory bloat & who really writes the laws (12:09) The path to victory: the persuadable voter, the cost-of-living pitch & the case against Becerra (21:46) Spencer Pratt joins: the message that cut through & the LA race that flipped…

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  14. 427
    Blake Scholl: Why Plane Speed Stalled, Supersonic Commercial Flight, & Revolutionizing the Engine22 Sept 2026 · 18 minBlake Scholl
    About this episode

    (0:00) Welcome Blake Scholl! (5:11) Solving the sonic boom & legalizing supersonic flight (7:59)  The pivot to powering data centers (10:38) Jason joins: data center demand, private jets & what winning looks like Thanks to our partners for making this possible! IREN is a vertically integrated AI Cloud platform,…

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  15. 426
    Naveen Rao: 4D Computing, AI's Energy Wall & Beating Biology21 Sept 2026 · 23 minNaveen Rao
    About this episode

    (0:00) Welcome Naveen Rao (4:45) Is energy really the problem? The cost of a token, power contracts & the gap to close (10:24) Cutting out the middleman: abstractions, dynamical systems & a new kind of machine (19:46) Chamath joins: the path to product, porting existing models & building the team Thanks to our…

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  16. 425
    Adam Foroughi, Applovin CEO: Surviving a 92% Drawdown, Ads as ML 1.0 & the $50B Game Ad Market20 Sept 2026 · 24 minAdam Foroughi
    About this episode

    (0:00) Adam Foroughi joins the Besties! (3:07) Discovery vs search & is your phone listening? (10:04) IPO tumble & becoming your own best investor (16:00) Privacy rules, Apple's crackdown & how agents change people's shopping (20:00) How a lean team beats the giants, margin moats & building in China Thanks to our…

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  17. 424
    Bill Gurley: Searching for Feynman19 Sept 2026 · 38 minBill Gurley
    About this episode

    (0:00) Bill Gurley takes the stage at the All-In Summit (1:29) Bill's Presentation: Searching for Feynman Links to additional resources mentioned in talk and used in research:  https://www.p3.institute/searching_for_feynman_resource_links.html Thanks to our partners for making this possible! IREN is a vertically…

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  18. 423
    Jared Isaacman: A New Era for NASA and American Space Exploration18 Sept 2026 · 39 min
    About this episode

    (0:00) NASA Administrator Jared Isaacman lays out the state and future of NASA (17:59) Moon base, creating new space industries, NASA's next chapter (23:29) How to make Mars realistic (25:30) Recruiting, moonshots, the "Nuclear NASA," new vehicles and the importance of humans in space (32:43) Allocating capital…

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  19. 422
    Nick Shirley: Exposing Government Fraud, Suing California & Taking on the Media18 Sept 2026 · 33 min
    About this episode

    (0:00) Nick Shirley debuts his new video: "Inside California's High Speed Rail to Nowhere" (11:42) Nick joins The Besties to discuss California's "Stop Nick Shirley Act" and recent fraud arrests (17:03) How he got into investigative journalism and finding fraud (23:32) Selective journalism and why Nick is a major…

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  20. 421
    Meta's Dina Powell McCormick: The Case for Data Centers, Backlash, AI Job Boom & Meta's Future17 Sept 2026 · 44 min
    About this episode

    (0:00) Dina Powell McCormick joins The Besties! (1:52) Impact of Meta's data center in Richland Parish, LA: $50K teacher checks, revitalizing a small town community (11:52) How Meta is alleviating data center concerns: pollution, electricity, water, noise, aesthetics; Misinformation campaigns (19:57) America's…

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  21. 420
    Brad Gerstner: No AI Bubble, Semis Eat the Nasdaq & AI's Take Off Problem17 Sept 2026 · 18 minBrad Gerstner
    About this episode

    (0:00) Welcome Brad Gerstner! (1:01) Trump Accounts, Every Child a Capitalist & The CAC Scan (5:07) Can AI revenue pay for the CapEx? (8:53) The Build Out Issue: Gigawatts, TAM, Token Growth, and Margin Expansion (12:30) The risks: AI regulation, the nuclear precedent, power limits, and rising rates Thanks to our…

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  22. 419
    JD Vance on AI, Entitlement Fraud, Iran War, Israel, H-1B Abuse & the Midterms15 Sept 2026 · 28 min
    About this episode

    (0:00) VP JD Vance joins The Besties! (1:40) Assessing the Trump Admin so far: Border control, re-industrialization, inflation, Iran, government debt, anti-fraud (9:28) AI approach: Dealing with Doomerism, "Frankenstein," and AI negativity (16:23) H-1B abuse and the massive $1T+ of fraud in federal spending…

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  23. 418
    Satya Nadella on the AI Doomer Slowdown, Microsoft's Master Plan & Who Wins AI15 Sept 2026 · 37 minSatya Nadella
    About this episode

    (0:00) Satya Nadella joins The Besties! (0:55) Dario's blog, "pacing the frontier," common sense AI safety (6:28) The failure of AI CEO messaging, monitoring agents, what will a slowdown mean for new AI products? (14:22) Economic incentives for frontier lab doomerism, where the AI profits are (22:45) Microsoft's…

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  24. 417
    Elon Musk & Gwynne Shotwell on AI Risks and Peer Review, Starship, Terafab, SpaceX/Tesla Merger15 Sept 2026 · 1h 4mGwynne ShotwellElon Musk
    About this episode

    (0:00) SpaceX's Gwynne Shotwell joins The Besties! (1:45) Gwynne's SpaceX story, selling rockets, and working for Elon (6:45) Running modern day SpaceX: AI, Starlink, Rockets, and X (13:43) Direct to cell with Starlink, retiring rockets, competition (18:34) Data centers in space (22:00) Management at SpaceX…

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  25. 416
    Jensen Huang: The Doomer Hoax, Superintelligence Is Here, and The Future of AI (ft. President Trump)14 Sept 2026 · 47 min
    About this episode

    (0:00) Jensen Huang joins The Besties! (1:39) Thoughts on Dario's blog, Frontier Labs calling to slow down AI, and Doomer psychology (9:58) Sensible AI regulation and RSI (16:05) Hugging Face acquisition, future of Open Source, and the race with China (22:58) President Trump calls in live to discuss the Doomer…

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  26. 415
    AI Kills Everybody or Doomer Psyop? OpenAI's Math Breakthrough, Nike's $200B Collapse11 Sept 2026 · 1h 36m
    About this episode

    (0:00) Bestie intros! (0:35) AI Doomsday: Valid concern or Doomer psyop? (33:40) Steelmanning AI Doomsday scenarios and the impact on Anthropic's IPO (58:45) OpenAI says it cracked a 200 year old math problem, but did it front-run users with their own data? (1:19:55) Nike removed from S&P 100 after stock tanks…

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  27. 414
    GPT-6 Hits AGI? Tech Euphoria 2.0, SF Mansion Shortage, NYC Bans AI in Schools & Venezuela Oil Deal4 Sept 2026 · 1h 32m
    About this episode

    (0:00) Bestie intros: Happy 50th Chamath! (1:17) OpenAI releases GPT-6 Astra: Have they reached AGI? (19:01) All-In Summit: Scholarships available! (19:56) Dwarkesh's Hugging Face hack article sparks a Bernie Sanders AI ban (37:03) EAs, AI-brained influencers, and the conflicts of interest (59:26) Mamdani bans AI…

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  28. 413
    Nvidia's Historic Quarter, SaaS Comeback, Bessent vs Druck, America's Debt Crisis, Cancer Vaccine29 Aug 2026 · 1h 37m
    About this episode

    (0:00) Bestie intros: Recapping recent interviews and the state of American science (3:31) China's Robot Olympics, Optimus update, Grok Bot (9:05) Nvidia and Salesforce rip after big earnings: AI Capex Bubble and SaaSpocalypse narratives get reversed (33:32) Bessent gets called out by Druckenmiller for bond market…

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  29. 412
    Eric Weinstein: The State of American Science, Breakthrough Coverups, and the Danger of Physics26 Aug 2026 · 1h 30mEric Weinstein
    About this episode

    (0:00) Eric Weinstein joins the show! (03:09) Has American science stalled? Cowboy science, Fauci, and the scientific precariat (21:31) Weinstein's fix: Blow a hole in the Civil Rights Act, kill peer review, fund people not ideas (41:36) Ed Witten drove physics off a cliff, and is Renaissance Technologies a secret…

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  30. 411
    Michael Kratsios: Trump's Science Agenda, Anti-Science Claims, Fauci's Damage, DEI & China24 Aug 2026 · 56 min
    About this episode

    (0:00) Michael Kratsios joins the show! (01:56) Is this administration anti-science? The Nature poll, DEI grants, and $8B down the drain  (8:16) Climate science cuts: RCP 8.5 gets pulled and the "climate emergency" narrative collapses (13:45) $47B at NIH, Eroom's Law, and golden tickets: has American science…

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Firms named in its episodes, and people named in descriptions: talked about, rather than on the show.

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