Ecosystem map · Raleigh

Raleigh startup ecosystem map

74 startups based in Raleigh that have raised money in rounds we track, grouped by their main sector. Together they have raised $1.5B; Biotech is the biggest sector, with 18 companies.

74startups on the map
8sectors
$1.5Braised between them
Biotechmost funded sector

Biotech

18

AI

14

IT Services

9

Healthtech

8

Software

8

Fintech

7

Big Data & Analytics

5

Agtech

5

Segment by segment

Biotech

18 startups · $561M raised

  1. CaidyaCaidya is a clinical research organization that provides personalized solutions for various therapeutic areas.United States$165M
  2. Slate MedicinesSlate Medicines develops therapeutics that target Pituitary Adenylate Cyclase-Activating Polypeptide for migraine treatment and prevention.United States$130M
  3. Sprout PharmaceuticalsSprout Pharmaceuticals is a medical company that develops products for the treatment of female sexual dysfunction.United States$99M
  4. Bryn PharmaBryn Pharma is a pharmaceutical company focused on developing an affordable, needle-free epinephrine nasal spray for treating anaphylaxis.United States$72M
  5. HumanevaHumaneva is a healthacare research company that offers reliable clinical research data that empowers the medical community.United States$50M
  6. SignalPathSignalPath is the premier clinical trial technology partner for research sites and sponsors, focused on improving the ease and effUnited States$18M
  7. BEKHealthBEKhealth is an AI-powered clinical intelligence company that enhances electronic health record (EHR) data for clinical research.United States$9.0M
  8. SelSym BiotechSelsym Biotech is a biotechnology developer whose goal is to provide innovative platelet-mimetic therapies for the treatment.United States$3.5M

AI

14 startups · $294M raised

  1. Element451Element451 is an AI-first CRM and student engagement platform tailored for higher education institutions.United States$176M
  2. HowsoHowso is a technology company based in Raleigh, North Carolina, focused on developing an understandable AI decision system.United States$25M
  3. PryonPryon is an enterprise AI company that specializes in enhancing information retrieval through its core product, the Pryon Memory Layer.United States$25M
  4. InsightFinderInsightFinder is a software company that provides monitoring and predictive analytics services for IT operations.United States$17M
  5. Lucem HealthLucem Health is a healthcare technology company based in Raleigh, North Carolina, founded in 2021.United States$16M
  6. ProximalProximal is a studio for creating learning environments in the virtual space.United States$15M
  7. UviquityUviquity is a deep-tech photonics company based in Raleigh, North Carolina.United States$9.1M
  8. InsureLifePre-commercial AI-execution control infrastructure at the boundary between AI intent and consequential enterprise action.United States$4.7M

IT Services

9 startups · $58M raised

  1. InfrascaleInfrascale is a DRaaS company that uses the cloud to eradicate downtime.United States$25M
  2. Lightforge GamesLightforge Games is a remote video game studio founded in 2020 by veterans from Blizzard and Epic Games.United States$15M
  3. IntervolveIn today's rapidly changing and fast paced beer market, wholesalers need an easy to use, state of the art Route Accounting System United States$8.0M
  4. DropsourceDropsource is a mobile development agency based in Raleigh, NC, established in 2014.United States$5.3M
  5. UserVoiceUserVoice is a provider of enterprise-grade product feedback management software that helps businesses gather, analyze, and act onUnited States$1.8M
  6. QoreboardOur mission is to change lives by inspiring and enabling individuals, teams and organizations to tap into their unrealized potentiUnited States$1.6M
  7. LogicBayLogicBay is an IT services and consulting company based in Raleigh, North Carolina.United States$536K
  8. Hosted AmericaHosted America is a fiber internet and communications provider that delivers connectivity services for both residential and busineUnited States$500K

Healthtech

8 startups · $172M raised

  1. Tryton MedicalTryton Medical manufactures and sells stent systems for the treatment of bifurcation lesions.United States$86M
  2. Lumata HealthLumata Health is a healthcare company focused on preventing preventable blindness.United States$46M
  3. Contego MedicalContego Medical develops a family of novel embolic protection devices.United States$29M
  4. Cerula CareCerula Care is a virtual-first behavioral health company founded in 2023 by psycho-oncologist Supriya Laknidhi.United States$5.5M
  5. ACAdvanced Chemotherapy TechnologiesAdvanced Chemotherapy Technologies is a startup developing a device that can infuse chemotherapies into poorly vascularized tumors.United States$4.0M
  6. Intake HealthA continuous, passive, home-health remote monitoring platform.United States$1.0M
  7. Ivy CliniciansIvy Clinicians is a healthcare startup based in Raleigh, NC, founded in 2021.United States$310K
  8. SecmationSecmation offers technology, engineering solutions, and tools to integrate information security into industrial and defense products.United States$59K

Software

8 startups · $36M raised

  1. Arroyo Video SolutionsArroyo Video Solutions (now acquired by Cisco) is a video on demand company based in the United States.United States$25M
  2. KnowledgeTreeOur sales enablement & sales acceleration software predicts winning content that boosts rep productivity, advances sales, & closes deals.United States$7.6M
  3. Entigral SystemsEntigral Systems is a developer of a sensor automation platform used for rapid, measurable improvements for asset management and tracking.United States$1.7M
  4. Cirrus InsightCirrus Insight automatically keeps Salesforce CRM up to date for sales teams from Gmail, Outlook, and Mobile.United States$550K
  5. trinketTrinket is the easiest way to make your class website interactive.United States$425K
  6. Power Analytics CorporationPower Analytics Corporation develops software for electrical power system design, simulation, nd power analytics.United States$384K
  7. Active Location Inc.Active LocationTM is a provider of our "patent pending", Location Technology Platform, enabling advertisers to deliver advertisingUnited States$250K
  8. SLEDVisionSLEDVision provides vendor relationship management solutions for the state, local, government and education (SLED) customers.United States$30K

Fintech

7 startups · $49M raised

  1. AdvisorEngineAdvisorEngine is a next-generation wealth management platform for investment advisors to help grow their business.United States$20M
  2. CertificialCertificial is a Smart COI (Certificate of Insurance) platform based in Holly Springs, North Carolina, founded in 2019.United States$15M
  3. FinmarkFinmark is financial planning software for startups; making it simple for companies to manage their runway, hiring, and cash.United States$6.5M
  4. Thread CapitalThread Capital is a dynamic organization that focuses on offering capital, coaching and connections to various businesses within the region.United States$5.0M
  5. Vista Index ServicesVista Index Services is a financial index provider specializing in the U.S.United States$1.4M
  6. LSLafayette StandardLafayette Standard is an investment company that acts as an incubator to support and activate new businesses.United States$600K
  7. Carloina Community ImpactCarolina Community Impact provides access to credit and asset-building techniques for individuals and businesses.United States$549K

Big Data & Analytics

5 startups · $275M raised

  1. PendoPendo is a product experience platform that specializes in software usage analytics and digital adoption solutions.United States$258M
  2. AnexioANEXIO is a prominent Infrastructure as a Service (IaaS) provider based in Raleigh, North Carolina.United States$8.0M
  3. Greenlight HealthGreenlight Health specializes in providing health data services.United States$4.2M
  4. Reveal MobileReveal Mobile provides location-based marketing, analytics, and attribution for agencies, brands, media companies, and app publishers.United States$2.5M
  5. LiineLiine simplifies and improves patient acquisition for growth-focused healthcare practices.United States$1.8M

Agtech

5 startups · $20M raised

  1. Hoofprint BiomeHoofprint Biome is an agricultural biotechnology company based in Raleigh, North Carolina, founded in 2023.United States$15M
  2. Plant Health CarePlant Health Care is a leading provider of scientifically proven biological products for the agricultural industry.United States$3.6M
  3. Harpe BioHarpe Bio develops sustainable weed control solutions for organic and industrial agriculture.United States$975K
  4. AGEYEAGEYE, also known as AgEye, is an AI-first indoor farming technology company based in Raleigh, North Carolina, with an engineeringUnited States$515K
  5. Shepherd FarmingShepherd is a digital labor platform designed specifically for farms and agriculture operations.United States$100K

How this map is made. Every startup here is based in Raleigh and has raised money in rounds we track. Each sits under its main sector, read from its rounds; each sector shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

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