Top list · Irvine

Startups in Irvine

166 startups in Irvine have raised money in rounds we track. These are the 50 that have raised the most, $16B between them.

$16Braised by these 50
166on our record in all
Rivianraised the most
  1. 1RivianRivian is an automotive technology company that develops products and services to advance the shift to sustainable mobility.

    Rivian is an automotive technology company that develops products and services to advance the shift to sustainable mobility.

    Founded 2009Irvine, United States$9.2Blast round Jul 2025
  2. 2American Healthcare REITAmerican Healthcare REIT provides and offers financial support and assistance on buildings.

    American Healthcare REIT provides and offers financial support and assistance on buildings.

    Founded 2011Irvine, United States$1.2Blast round May 2026
  3. 3FieldAIFieldAI is the general-purpose brain making robots autonomous in complex, risky, real-world environments.

    FieldAI is the general-purpose brain making robots autonomous in complex, risky, real-world environments.

    Founded -Irvine, United States$1.1Blast round Oct 2026
  4. 4AcornsAcorns is a global financial wellness app that focuses on micro-investing, helping everyday people and families save and invest small amounts of money for long-

    Acorns is a global financial wellness app that focuses on micro-investing, helping everyday people and families save and invest small amounts of money for long-

    Founded 2012Irvine, United States$438Mlast round Mar 2022
  5. 5Celero CommunicationsCelero Communications is a semiconductor company founded in 2024, based in Irvine, California, with design centers in Canada and Argentina.

    Celero Communications is a semiconductor company founded in 2024, based in Irvine, California, with design centers in Canada and Argentina.

    Founded 2024Irvine, United States$375Mlast round Sept 2026
  6. 6Beta BionicsBeta Bionics is a biotechnology company that develops an integrated bionic pancreas system called the iLet.

    Beta Bionics is a biotechnology company that develops an integrated bionic pancreas system called the iLet.

    Founded 2015Irvine, United States$296Mlast round Sept 2026
  7. 7Solarflare CommunicationsSolarflare Communications is a technology company based in Irvine, California, founded in 2001.

    Solarflare Communications is a technology company based in Irvine, California, founded in 2001.

    Founded 2001Irvine, United States$243Mlast round Jan 2015
  8. 8CG OncologyCG Oncology is a clinical-stage biopharmaceutical company focused on the development of oncolytic immunotherapies to combat cancer.

    CG Oncology is a clinical-stage biopharmaceutical company focused on the development of oncolytic immunotherapies to combat cancer.

    Founded 2010Irvine, United States$238Mlast round Dec 2024
  9. 9Menlo MicroMenlo Micro is a semiconductor technology company based in Irvine, California, founded in December 2016 as a spin-out from General Electric.

    Menlo Micro is a semiconductor technology company based in Irvine, California, founded in December 2016 as a spin-out from General Electric.

    Founded 2016Irvine, United States$213Mlast round Mar 2022
  10. 10Restaurant365Restaurant365 is an enterprise management software for restaurants that provides accounting, inventory, scheduling, and payroll solutions.

    Restaurant365 is an enterprise management software for restaurants that provides accounting, inventory, scheduling, and payroll solutions.

    Founded 2011Irvine, United States$195Mlast round May 2024
  11. 11EvolusEvolus medical aesthetics focused on providing physicians and their patients with expanded choices in aesthetic procedures and treatments.

    Evolus medical aesthetics focused on providing physicians and their patients with expanded choices in aesthetic procedures and treatments.

    Founded 2012Irvine, United States$150Mlast round May 2025
  12. 12Axonics Modulation TechnologiesAxonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation.

    Axonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation.

    Founded 2012Irvine, United States$144Mlast round Aug 2022
  13. 13Auction.comAuction.com is the largest online marketplace for foreclosure and bank-owned real estate auctions in the United States.

    Auction.com is the largest online marketplace for foreclosure and bank-owned real estate auctions in the United States.

    Founded 2007Irvine, United States$142Mlast round Mar 2014
  14. 14Cloudbreak TherapeuticsCloudbreak Therapeutics is a clinical stage biotechnology company

    Cloudbreak Therapeutics is a clinical stage biotechnology company

    Founded 2015Irvine, United States$130Mlast round Jan 2022
  15. 15Ambros TherapeuticsAmbros Therapeutics is a clinical-stage biotechnology company.

    Ambros Therapeutics is a clinical-stage biotechnology company.

    Founded -Irvine, United States$125Mlast round Dec 2025
  16. 16Tarsus PharmaceuticalsTarsus Pharmaceuticals is a clinical-stage biopharmaceutical company that develops treatments for diseases with high unmet need.

    Tarsus Pharmaceuticals is a clinical-stage biopharmaceutical company that develops treatments for diseases with high unmet need.

    Founded 2017Irvine, United States$125Mlast round Mar 2025
  17. 17Turion SpaceTurion Space is an aerospace and defense company based in Irvine, California, founded in 2021 by a team from SpaceX.

    Turion Space is an aerospace and defense company based in Irvine, California, founded in 2021 by a team from SpaceX.

    Founded 2021Irvine, United States$115Mlast round Apr 2026
  18. 18Spot RunnerSpot Runner, Inc - The world's first TV advertising platform for local advertisers.

    Spot Runner, Inc - The world's first TV advertising platform for local advertisers.

    Founded 2003Irvine, United States$101Mlast round May 2008
  19. 19HypericeOur mission is simple - to help everyone on Earth move better, live better and be better.

    Our mission is simple - to help everyone on Earth move better, live better and be better.

    Founded 2011Irvine, United States$100Mlast round Jul 2023
  20. 20WiSpryWiSpry, a fabless semiconductor company, develops RF silicon integrated circuits and components for wireless communication products.

    WiSpry, a fabless semiconductor company, develops RF silicon integrated circuits and components for wireless communication products.

    Founded 2002Irvine, United States$71Mlast round Jul 2014
  21. 21Terran OrbitalTerran Orbital is a leading manufacturer of small satellites primarily serving the United States and Allied aerospace and defense industries.

    Terran Orbital is a leading manufacturer of small satellites primarily serving the United States and Allied aerospace and defense industries.

    Founded 2013Irvine, United States$69Mlast round Sept 2023
  22. 22BlueCavaBlueCava is a fast growing provider of cross screen reach, targeting and measurement products for brands, advertisers, data companies and adtech players.

    BlueCava is a fast growing provider of cross screen reach, targeting and measurement products for brands, advertisers, data companies and adtech players.

    Founded 2010Irvine, United States$65Mlast round Sept 2015
  23. 23NeomendNeomend is a biomedical device company engaged in the development and commercialization of surgical wound healing products.

    Neomend is a biomedical device company engaged in the development and commercialization of surgical wound healing products.

    Founded 1999Irvine, United States$62Mlast round Aug 2011
  24. 24Greenwave SystemsGreenwave Systems is a software and services company that leverages Internet of Things technologies to help clients deploy managed services.

    Greenwave Systems is a software and services company that leverages Internet of Things technologies to help clients deploy managed services.

    Founded 2008Irvine, United States$60Mlast round May 2016
  25. 25Casa Azul SpiritsCasa Azul Spirits specializes in the production of alcoholic beverages, particularly tequila.

    Casa Azul Spirits specializes in the production of alcoholic beverages, particularly tequila.

    Founded 2021Irvine, United States$58Mlast round Aug 2021
  26. 26SilveradoSilverado Senior Living, based in Irvine, California, specializes in memory care and assisted living for individuals with memory impairments, such as Alzheimer’

    Silverado Senior Living, based in Irvine, California, specializes in memory care and assisted living for individuals with memory impairments, such as Alzheimer’

    Founded 1996Irvine, United States$51Mlast round Jun 2018
  27. 27DrybarDrybar is a retail chain exclusively for blow-drying hair for a reduced price compared to traditional salons.

    Drybar is a retail chain exclusively for blow-drying hair for a reduced price compared to traditional salons.

    Founded 2009Irvine, United States$51Mlast round Jun 2014
  28. 28In-Charge EnergyIn-Charge Energy is an energy solutions company that is accelerating electrification of the transportation industry.

    In-Charge Energy is an energy solutions company that is accelerating electrification of the transportation industry.

    Founded -Irvine, United States$46Mlast round Jun 2026
  29. 29Vascular DynamicsVascular Dynamics is a medical device company founded in 2008 and headquartered in Irvine, California.

    Vascular Dynamics is a medical device company founded in 2008 and headquartered in Irvine, California.

    Founded 2008Irvine, United States$46Mlast round Mar 2017
  30. 30UplogixUplogix provides network monitoring and management solutions that improve control, connectivity and security.

    Uplogix provides network monitoring and management solutions that improve control, connectivity and security.

    Founded 2003Irvine, United States$45Mlast round Feb 2014
  31. 31INBRACESwift Health Systems is a stealth stage start-up medical device company, developing INBRACE.

    Swift Health Systems is a stealth stage start-up medical device company, developing INBRACE.

    Founded 2014Irvine, United States$45Mlast round Jul 2022
  32. 32Local.comLocal.com owns and operates a leading local search site and network in the United States.

    Local.com owns and operates a leading local search site and network in the United States.

    Founded 2015Irvine, United States$43Mlast round Jan 2024
  33. 33Irvine Sensors CorporationIrvine Sensors Corporation is a California-based company specializing in sensor systems, particularly in advanced imaging, video analytics, and intelligent sens

    Irvine Sensors Corporation is a California-based company specializing in sensor systems, particularly in advanced imaging, video analytics, and intelligent sens

    Founded 2013Irvine, United States$42Mlast round Nov 2013
  34. 34Red 5 StudiosRed 5 Studios was an American video game development company founded in 2005-2006 by former Blizzard Entertainment employees, including Mark E.

    Red 5 Studios was an American video game development company founded in 2005-2006 by former Blizzard Entertainment employees, including Mark E.

    Founded 2006Irvine, United States$42Mlast round Mar 2010
  35. 35AlternativAlternativ is a financial firm that specializes in wealth advisory with a focus on alternative assets.

    Alternativ is a financial firm that specializes in wealth advisory with a focus on alternative assets.

    Founded 2021Irvine, United States$41Mlast round Sept 2023
  36. 36MovandiMovandi is a semiconductor and systems innovator focused on next-generation wireless communications, particularly in 5G millimeter-wave (mmWave) technology.

    Movandi is a semiconductor and systems innovator focused on next-generation wireless communications, particularly in 5G millimeter-wave (mmWave) technology.

    Founded 2016Irvine, United States$40Mlast round Oct 2025
  37. 37SyntiantSyntiant is a deep learning tech company providing AI voice and sensor solutions.

    Syntiant is a deep learning tech company providing AI voice and sensor solutions.

    Founded 2017Irvine, United States$40Mlast round Mar 2026
  38. 38FugooFugoo has a long history in strategic product design of hardware and software.

    Fugoo has a long history in strategic product design of hardware and software.

    Founded 2009Irvine, United States$40Mlast round Oct 2009
  39. 39Breathe TechnologiesBreathe Technologies provide healthcare providers and patients with respiratory therapies that optimize breathing and mobility.

    Breathe Technologies provide healthcare providers and patients with respiratory therapies that optimize breathing and mobility.

    Founded 2005Irvine, United States$39Mlast round Jan 2015
  40. 40PatientFiPatientFi is a financial technology company based in Irvine, California, that focuses on modernizing healthcare financing.

    PatientFi is a financial technology company based in Irvine, California, that focuses on modernizing healthcare financing.

    Founded 2017Irvine, United States$38Mlast round Jun 2026
  41. 41WebVisibleWebVisible, Inc.

    WebVisible, Inc.

    Founded 2001Irvine, United States$37Mlast round Feb 2010
  42. 42AgendiaAgendia is a molecular diagnostics company focused on precision oncology, specifically for early-stage breast cancer.

    Agendia is a molecular diagnostics company focused on precision oncology, specifically for early-stage breast cancer.

    Founded 2003Irvine, United States$35Mlast round Jul 2018
  43. 43AcclarentAcclarent is a medical device company that develops new technologies to treat patients suffering from ENT disorders.

    Acclarent is a medical device company that develops new technologies to treat patients suffering from ENT disorders.

    Founded 2004Irvine, United States$35Mlast round Apr 2007
  44. 44lensgenLensGen creates adaptive intraocular lenses for the treatment of presbyopia.

    LensGen creates adaptive intraocular lenses for the treatment of presbyopia.

    Founded 2011Irvine, United States$34Mlast round Aug 2020
  45. 45NGD SystemsNGD Systems manufactures the world’s most advanced computational storage drives (CSDs) that allow customers to compute anywhere.

    NGD Systems manufactures the world’s most advanced computational storage drives (CSDs) that allow customers to compute anywhere.

    Founded 2013Irvine, United States$32Mlast round Feb 2020
  46. 46NumecentNumecent develops a 'cloudpaging' technology that transmits pre-virtualized native software instructions in a transient manner.

    Numecent develops a 'cloudpaging' technology that transmits pre-virtualized native software instructions in a transient manner.

    Founded 2012Irvine, United States$31Mlast round Nov 2015
  47. 47TAE Life SciencesTAE Life Sciences is a biotechnology company founded in 2017 and based in Irvine, California.

    TAE Life Sciences is a biotechnology company founded in 2017 and based in Irvine, California.

    Founded 2017Irvine, United States$30Mlast round Jun 2020
  48. 48Seragon PharmaceuticalsSeragon Pharmaceuticals is a research-based company dedicated to improving human and animal health through innovative science.

    Seragon Pharmaceuticals is a research-based company dedicated to improving human and animal health through innovative science.

    Founded 2013Irvine, United States$30Mlast round Oct 2013
  49. 49Water Health InternationalWaterHealth International provides de-centralized, scalable, safe, and affordable water solutions.

    WaterHealth International provides de-centralized, scalable, safe, and affordable water solutions.

    Founded 1995Irvine, United States$29Mlast round Sept 2014
  50. 50SecureAuthSecureAuth is an identity and access management company that delivers a truly passwordless continuous experience to everyone, everywhere.

    SecureAuth is an identity and access management company that delivers a truly passwordless continuous experience to everyone, everywhere.

    Founded 2005Irvine, United States$28Mlast round Aug 2014
Total fundinghow the list is ranked
15 November 2026updated nightly
Rounds we tracksource: Millionrounds

Every startup we hold in Irvine, ranked by the total it has raised in rounds we hold. Nobody pays to be on a list.

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