Top list · Cleveland
Startups in Cleveland
81 startups in Cleveland have raised money in rounds we track. These are the 50 that have raised the most, $1.6B between them.
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FlexjetFlexjet is in the business of fractional aircraft and private jet sales.Flexjet is in the business of fractional aircraft and private jet sales.
Founded 1995Cleveland, United States$800Mlast round Jul 2025 - 2
EverstreamEverstream is a telecom company that provides fiber internet services to mid-sized and large enterprises and businesses.Everstream is a telecom company that provides fiber internet services to mid-sized and large enterprises and businesses.
Founded 2014Cleveland, United States$148Mlast round May 2022 - 3
SPR TherapeuticsSPR Therapeutics is a medical device company.SPR Therapeutics is a medical device company.
Founded 2010Cleveland, United States$101Mlast round Feb 2024 - 4
Splash FinancialSplash is a leading digital lending platform that helps borrowers easily shop and compare financial products from our network of lendersSplash is a leading digital lending platform that helps borrowers easily shop and compare financial products from our network of lenders
Founded 2015Cleveland, United States$74Mlast round Sept 2025 - 5
ChampSaaS solutions to create, manage and transfer digital vehicle titles for insurance carriers, lenders, state govt, vehicle retailers and OEMsSaaS solutions to create, manage and transfer digital vehicle titles for insurance carriers, lenders, state govt, vehicle retailers and OEMs
Founded 2018Cleveland, United States$73Mlast round Dec 2025 - 6
Cleveland HeartLabCleveland HeartLab is a clinical laboratory and disease management firm, develops biomarker technologies and diagnostic tests.
Cleveland HeartLab is a clinical laboratory and disease management firm, develops biomarker technologies and diagnostic tests.
Founded 2000Cleveland, United States$51Mlast round Jul 2014 - 7
Juventas TherapeuticsJuventas is a biotechnology company that discovers and develops non-viral gene therapies for the treatment of chronic cardiovascular diseases.Juventas is a biotechnology company that discovers and develops non-viral gene therapies for the treatment of chronic cardiovascular diseases.
Founded 2007Cleveland, United States$41Mlast round May 2015 - 8
Eagle WirelessEagle Wireless is a connectivity company that specializes in secure, high-performance IoT and automotive connectivity solutions.Eagle Wireless is a connectivity company that specializes in secure, high-performance IoT and automotive connectivity solutions.
Founded 2025Cleveland, United States$30Mlast round Feb 2026 - 9
Checkpoint SurgicalCheckpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures.Checkpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures.
Founded 2009Cleveland, United States$23Mlast round Jun 2024 - 10
Bravo WellnessSince 2008, Bravo Wellness has changed the landscape of what a results-based wellness incentive plan can provide.Since 2008, Bravo Wellness has changed the landscape of what a results-based wellness incentive plan can provide.
Founded 2008Cleveland, United States$22Mlast round Aug 2014 - 11
AdmiralAdmiral is a printing company offering graphic design, marketing, mailing, bindery, and finishing services.Admiral is a printing company offering graphic design, marketing, mailing, bindery, and finishing services.
Founded 1950Cleveland, United States$22Mlast round Aug 2024 - 12
Vox MobileVox Mobile offers complete enterprise mobility including mobile technology consulting, management, and support to companies.Vox Mobile offers complete enterprise mobility including mobile technology consulting, management, and support to companies.
Founded 2006Cleveland, United States$18Mlast round Jun 2015 - 13
Cleveland DiagnosticsCleveland Diagnostics is a precision oncology and cancer biotechnology company based in Cleveland, Ohio.Cleveland Diagnostics is a precision oncology and cancer biotechnology company based in Cleveland, Ohio.
Founded 2013Cleveland, United States$16Mlast round Oct 2025 - 14
StreamLink SoftwareStreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector.StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector.
Founded 2008Cleveland, United States$15Mlast round Jun 2016 - 15
Sonic Fire TechSonic Fire Tech is a Cleveland-based company specializing in fire-suppression technology.Sonic Fire Tech is a Cleveland-based company specializing in fire-suppression technology.
Founded 2019Cleveland, United States$15Mlast round Aug 2026 - 16
OnShiftOnShift delivers cloud-based human capital management software and proactive services to solve everyday workforce challenges in healthcare.OnShift delivers cloud-based human capital management software and proactive services to solve everyday workforce challenges in healthcare.
Founded 2008Cleveland, United States$14Mlast round Feb 2014 - 17
SparkBaseSparkBase is a gift card and loyalty software platform based in Cleveland, Ohio, founded in 2004.SparkBase is a gift card and loyalty software platform based in Cleveland, Ohio, founded in 2004.
Founded 2004Cleveland, United States$11Mlast round Jan 2013 - 18
AxuallAxuall is a workforce intelligence company based in Cleveland, Ohio, focused on enhancing clinical workforce management in the healthcare sector.Axuall is a workforce intelligence company based in Cleveland, Ohio, focused on enhancing clinical workforce management in the healthcare sector.
Founded 2018Cleveland, United States$10Mlast round Aug 2023 - 19
OarexOAREX is a capital partner built for the modern media industry.OAREX is a capital partner built for the modern media industry.
Founded 2012Cleveland, United States$10Mlast round Oct 2017 - 20
AthersysAthersys is a clinical stage biopharmaceutical company with a growing pipeline of highly differentiated, potential best in class therapeutics to treat significaAthersys is a clinical stage biopharmaceutical company with a growing pipeline of highly differentiated, potential best in class therapeutics to treat significa
Founded 1995Cleveland, United States$9.0Mlast round Mar 2012 - 21
Diasome PharmaceuticalsDiasome Pharmaceuticals is a clinical-stage diabetes therapeutics company that designs and develops insulin-based therapies.Diasome Pharmaceuticals is a clinical-stage diabetes therapeutics company that designs and develops insulin-based therapies.
Founded 2004Cleveland, United States$9.0Mlast round Jun 2023 - 22
ThrivableThrivable's innovative platform makes it quicker and easier than ever to find and connect with patients for top quality insights.Thrivable's innovative platform makes it quicker and easier than ever to find and connect with patients for top quality insights.
Founded 2019Cleveland, United States$8.7Mlast round Oct 2025 - 23ComplionComplion is a clinical research software company based in Cleveland, Ohio, founded in 2013.
Complion is a clinical research software company based in Cleveland, Ohio, founded in 2013.
Founded 2013Cleveland, United States$8.7Mlast round Feb 2019 - 24Securus Medical GroupSecurus Medical Group develops clinical tools for monitoring core body temperature within body cavities.
Securus Medical Group develops clinical tools for monitoring core body temperature within body cavities.
Founded 2011Cleveland, United States$7.5Mlast round Oct 2013 - 25
Cell X TechnologiesCell X Technologies is a leader in cell processing, specializing in the commercialization of autologous and allogeneic cell therapies.Cell X Technologies is a leader in cell processing, specializing in the commercialization of autologous and allogeneic cell therapies.
Founded 2019Cleveland, United States$6.0Mlast round Aug 2024 - 26
Sundays for DogsSundays for Dogs is a Cleveland, Ohio-based pet food company that specializes in human-grade, air-dried dog food.Sundays for Dogs is a Cleveland, Ohio-based pet food company that specializes in human-grade, air-dried dog food.
Founded 2020Cleveland, United States$6.0Mlast round Oct 2023 - 27
TandemStrideTandemStride is a trauma recovery support company focused on helping individuals recover from traumatic injuries.TandemStride is a trauma recovery support company focused on helping individuals recover from traumatic injuries.
Founded 2023Cleveland, United States$5.5Mlast round Sept 2025 - 28
Embrace Pet InsuranceEmbrace Pet Insurance is a provider of pet insurance policies for dogs and cats.Embrace Pet Insurance is a provider of pet insurance policies for dogs and cats.
Founded 2005Cleveland, United States$5.3Mlast round May 2014 - 29
Imalux CorporationThrough the use of its Niris Imaging System, Imalux Corporation offers physicians a tool to support our goal – or at least reduce the number of visits necessaryThrough the use of its Niris Imaging System, Imalux Corporation offers physicians a tool to support our goal – or at least reduce the number of visits necessary
Founded 1996Cleveland, United States$5.1Mlast round Sept 2007 - 30
S4 MedicalS4 Medical Corp is a Cleveland-based medical device company founded in 2017.S4 Medical Corp is a Cleveland-based medical device company founded in 2017.
Founded 2017Cleveland, United States$5.0Mlast round Jul 2023 - 31
Biohm TechnologiesBiohm Technologies is a microbiome innovation company based in Cleveland, Ohio, founded in 2016 by Dr.Biohm Technologies is a microbiome innovation company based in Cleveland, Ohio, founded in 2016 by Dr.
Founded 2016Cleveland, United States$4.5Mlast round Apr 2025 - 32
Drive My WayDrive My Way is a Cleveland-based software-as-a-service (SaaS) company founded in 2014.Drive My Way is a Cleveland-based software-as-a-service (SaaS) company founded in 2014.
Founded 2014Cleveland, United States$4.4Mlast round Sept 2022 - 33
GraffleOur thin layer over the Flow blockchain allows developers to read, write, and query the blockchain using any language.Our thin layer over the Flow blockchain allows developers to read, write, and query the blockchain using any language.
Founded 2021Cleveland, United States$4.3Mlast round Jan 2022 - 34
CoologicsCoologics is a medical device company focused on developing drug-free treatments for vaginal infections.Coologics is a medical device company focused on developing drug-free treatments for vaginal infections.
Founded -Cleveland, United States$4.0Mlast round Sept 2026 - 35
Trade HoundsTrade Hounds is a mobile application and digital platform tailored for the skilled trades community in the United States.Trade Hounds is a mobile application and digital platform tailored for the skilled trades community in the United States.
Founded 2019Cleveland, United States$3.2Mlast round Jun 2020 - 36
NavAgenticNavAgentic is all-in-one resource to find jobs and build your skills.NavAgentic is all-in-one resource to find jobs and build your skills.
Founded 2021Cleveland, United States$3.0Mlast round May 2023 - 37
Cleveland KitchenCleveland Kitchen offers probiotic-packed krauts and fermented dressings and marinades.Cleveland Kitchen offers probiotic-packed krauts and fermented dressings and marinades.
Founded 2013Cleveland, United States$2.9Mlast round Jul 2026 - 38
LineStream TechnologiesLineStream Technologies is a software-centric provider of motor and motion control solutions, established in 2008 as a spinoff from Cleveland State University.LineStream Technologies is a software-centric provider of motor and motion control solutions, established in 2008 as a spinoff from Cleveland State University.
Founded 2006Cleveland, United States$2.5Mlast round Sept 2015 - 39
ReadySet SurgicalReadySet Surgical is a surgical coordination platform that simplifies the surgical vendor supply chain.ReadySet Surgical is a surgical coordination platform that simplifies the surgical vendor supply chain.
Founded 2015Cleveland, United States$2.3Mlast round Jul 2025 - 40
Great Lakes NeuroTechnologies Inc.Pioneering innovative biomedical technologiesPioneering innovative biomedical technologies
Founded 2010Cleveland, United States$2.1Mlast round Aug 2025 - 41
MedPilotMedPilot is an AI-driven patient experience platform.MedPilot is an AI-driven patient experience platform.
Founded 2014Cleveland, United States$2.0Mlast round Jan 2020 - 42
KeborMedKeborMed is a healthcare technology company based in Cleveland, Ohio.KeborMed is a healthcare technology company based in Cleveland, Ohio.
Founded 2017Cleveland, United States$1.9Mlast round May 2022 - 43
XploroXploro® is a patient education platform that enhances how young patients engage with their healthcare.Xploro® is a patient education platform that enhances how young patients engage with their healthcare.
Founded 2019Cleveland, United States$1.7Mlast round Feb 2025 - 44
WizestWizest is an investment platform that simplifies stock trading and portfolio management for everyday investors.Wizest is an investment platform that simplifies stock trading and portfolio management for everyday investors.
Founded 2019Cleveland, United States$1.7Mlast round Nov 2021 - 45
BeanBean is an AI-powered accounting automation company that offers the Bean Intelligence platform.Bean is an AI-powered accounting automation company that offers the Bean Intelligence platform.
Founded 2021Cleveland, United States$1.6Mlast round Jul 2022 - 46
GenomOncologyGenomOncology enables precision medicine by translating next generation sequencing data into actionable information.GenomOncology enables precision medicine by translating next generation sequencing data into actionable information.
Founded 2012Cleveland, United States$1.5Mlast round Feb 2014 - 47
TPA StreamTPA Stream is a SaaS company that delivers cloud-based claims data and software for next generation benefits.TPA Stream is a SaaS company that delivers cloud-based claims data and software for next generation benefits.
Founded 2014Cleveland, United States$1.4Mlast round Sept 2019 - 48VIPerksviperks is a cloud based employee discount and appreciation platform.
viperks is a cloud based employee discount and appreciation platform.
Founded 2014Cleveland, United States$1.4Mlast round Jan 2017 - 49
EverykeyEverykey is a offers a Bluetooth device designed to replace keys and passwords.
Everykey is a offers a Bluetooth device designed to replace keys and passwords.
Founded 2015Cleveland, United States$1.1Mlast round Aug 2015 - 50
Milo BiotechnologyMilo Biotechnology develops technologies and programs to improve the lives of patients with neuromuscular diseases.
Milo Biotechnology develops technologies and programs to improve the lives of patients with neuromuscular diseases.
Founded 2011Cleveland, United States$1.1Mlast round Sept 2016
Cleveland, United StatesEvery startup we hold in Cleveland, ranked by the total it has raised in rounds we hold. Nobody pays to be on a list.
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