Top list · Worldwide
RNA therapeutics startups worldwide
59 RNA therapeutics startups worldwide have raised money in rounds we track. These are the 50 that have raised the most, $3.7B between them, with the United States the most common home.
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STORM TherapeuticsTargeting pathways that modify RNA to deliver novel cancer therapeuticsTargeting pathways that modify RNA to deliver novel cancer therapeutics
Founded 2015Cambridge, United Kingdom$317Mlast round Apr 2026 - 2
ReNAgade TherapeuticsReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease.ReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease.
Founded 2021Cambridge, United States$300Mlast round May 2023 - 3Orbital TherapeuticsOrbital Therapeutics is a biotechnology company that develops RNA-based medicines to treat disease in humans.
Orbital Therapeutics is a biotechnology company that develops RNA-based medicines to treat disease in humans.
Founded 2022New York, United States$270Mlast round Apr 2023 - 4
Strand TherapeuticsStrand Therapeutics is a biopharmaceutical company applying synthetic biology to RNA therapeutics to develop single dose mRNA treatments.Strand Therapeutics is a biopharmaceutical company applying synthetic biology to RNA therapeutics to develop single dose mRNA treatments.
Founded 2017Cambridge, United States$267Mlast round Mar 2026 - 5
Shape TherapeuticsA biotechnology company developing RNA technologies to shape the future of gene therapyA biotechnology company developing RNA technologies to shape the future of gene therapy
Founded 2018Seattle, United States$260Mlast round Jul 2026 - 6
Stoke TherapeuticsStoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.
Founded 2014Bedford, United States$255Mlast round Mar 2024 - 7
Orna TherapeuticsOrna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA therapeutics to treat various diseases.Orna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA therapeutics to treat various diseases.
Founded 2019Cambridge, United States$221Mlast round Aug 2022 - 8
Nutcracker TherapeuticsNutcracker Therapeutics is a biotechnology company based in Emeryville, California, specializing in mRNA therapeutics and a unique GMP manufacturing platform.Nutcracker Therapeutics is a biotechnology company based in Emeryville, California, specializing in mRNA therapeutics and a unique GMP manufacturing platform.
Founded 2018Emeryville, United States$167Mlast round Mar 2022 - 9
AIRNAAIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.AIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.
Founded 2021Cambridge, United States$155Mlast round Apr 2025 - 10
Skyhawk TherapeuticsSkyhawk Therapeutics is a clinical-stage biotechnology company located in Waltham, Massachusetts.Skyhawk Therapeutics is a clinical-stage biotechnology company located in Waltham, Massachusetts.
Founded 2016Waltham, United States$133Mlast round Sept 2021 - 11
Addition TherapeuticsAddition Therapeutics develops RNA-only therapeutics using PRINT technology for genetic medicine.Addition Therapeutics develops RNA-only therapeutics using PRINT technology for genetic medicine.
Founded -South San Francisco, United States$100Mlast round Dec 2025 - 12DTx PharmaDTx Pharma is a biotechnology company creating novel RNA-based therapeutics to treat the genetic drivers of disease.
DTx Pharma is a biotechnology company creating novel RNA-based therapeutics to treat the genetic drivers of disease.
Founded 2017San Diego$100Mlast round Mar 2021 - 13
Atalanta TherapeuticsAtalanta Therapeutics is a biotechnology company based in Boston, Massachusetts, focused on developing innovative therapies for central nervous system (CNS) diseases.Atalanta Therapeutics is a biotechnology company based in Boston, Massachusetts, focused on developing innovative therapies for central nervous system (CNS) diseases.
Founded 2018Boston, United States$97Mlast round Jan 2025 - 14
ProQR TherapeuticsChanging lives is what drives us at ProQR Therapeutics.Changing lives is what drives us at ProQR Therapeutics.
Founded 2012Leiden, Netherlands$68Mlast round Jun 2026 - 15Vivatides TherapeuticsVivatides Therapeutics develops RNA treatments to help improve patients' lives using biotechnology research.
Vivatides Therapeutics develops RNA treatments to help improve patients' lives using biotechnology research.
Founded -Woburn, United States$64Mlast round May 2026 - 16
Redona TherapeuticsRedona Therapeutics specializes in the modulation of functional non-coding RNA to treat cancer and other human diseases.Redona Therapeutics specializes in the modulation of functional non-coding RNA to treat cancer and other human diseases.
Founded 2016Watertown, United States$61Mlast round Jul 2023 - 17
Switch TherapeuticsSwitch Therapeutics is a preclinical-stage biotechnology company founded in 2020, focused on developing innovative RNA interference (RNAi) therapies for centralSwitch Therapeutics is a preclinical-stage biotechnology company founded in 2020, focused on developing innovative RNA interference (RNAi) therapies for central
Founded 2020San Francisco, United States$52Mlast round Mar 2023 - 18
Arnatar TherapeuticsArnatar Therapeutics is a biotechnology company founded in 2022, based in San Diego, California, with operations in Shanghai, China.Arnatar Therapeutics is a biotechnology company founded in 2022, based in San Diego, California, with operations in Shanghai, China.
Founded 2022San Diego, United States$52Mlast round Apr 2024 - 19NucleonicsNucleonics is a biotechnology company focused on RNA interference-based therapeutics.
Nucleonics is a biotechnology company focused on RNA interference-based therapeutics.
Founded 2001United States$49Mlast round Jun 2004 - 20
AerskaAerska is a biotechnology company focused on developing targeted RNA medicines to treat brain diseases.Aerska is a biotechnology company focused on developing targeted RNA medicines to treat brain diseases.
Founded -Dublin, Ireland$49Mlast round May 2026 - 21
Aptadir TherapeuticsAptadir Therapeutics is a biotechnology startup based in Milan, focused on developing RNA inhibitor-based therapies for cancer and genetic disorders.Aptadir Therapeutics is a biotechnology startup based in Milan, focused on developing RNA inhibitor-based therapies for cancer and genetic disorders.
Founded -Milano, United Kingdom$47Mlast round Sept 2026 - 22
NextRNA TherapeuticsNextRNA Therapeutics is a biotechnology company based in Boston, Massachusetts, focused on developing innovative therapies that target long non-coding RNAs (lncRNAs).NextRNA Therapeutics is a biotechnology company based in Boston, Massachusetts, focused on developing innovative therapies that target long non-coding RNAs (lncRNAs).
Founded 2020Boston, United States$47Mlast round Mar 2022 - 23
Starna TherapeuticsStarna Therapeutics is a biotechnology company based in Suzhou, China, founded in August 2021.Starna Therapeutics is a biotechnology company based in Suzhou, China, founded in August 2021.
Founded 2021Suzhou, China$42Mlast round Oct 2025 - 24
Argo BiopharmaArgo Biopharma is a clinical-stage biotechnology company based in Shanghai, China, founded in 2021.Argo Biopharma is a clinical-stage biotechnology company based in Shanghai, China, founded in 2021.
Founded 2021Shanghai, China$41Mlast round Nov 2023 - 25
ARTHEx BiotechARTHEx Biotech is a clinical-stage biotechnology company based in Paterna, Valencia, Spain.ARTHEx Biotech is a clinical-stage biotechnology company based in Paterna, Valencia, Spain.
Founded 2019Paterna, Spain$41Mlast round Sept 2025 - 26
SRTD BiotechSRTD Biotech GmbH is a biotechnology company based in Jülich, Germany, specializing in the development of RNA-based therapeutics.SRTD Biotech GmbH is a biotechnology company based in Jülich, Germany, specializing in the development of RNA-based therapeutics.
Founded -Juelich, Germany$35Mlast round Nov 2026 - 27AvidityAvidity is a RNA therapeutics software solutions provider company.
Avidity is a RNA therapeutics software solutions provider company.
Founded 1996Aurora, United States$32Mlast round Oct 2018 - 28
Ractigen TherapeuticsRactigen Therapeutics is a clinical-stage biopharmaceutical company based in Suzhou, Jiangsu, China, founded in 2016.Ractigen Therapeutics is a clinical-stage biopharmaceutical company based in Suzhou, Jiangsu, China, founded in 2016.
Founded 2017Suzhou, China$30Mlast round Jan 2022 - 29
CAMP4 TherapeuticsCAMP4 Therapeutics is a biotechnology company that uses RNA to restore healthy gene expression.CAMP4 Therapeutics is a biotechnology company that uses RNA to restore healthy gene expression.
Founded 2016Cambridge, United States$30Mlast round Dec 2025 - 30
OncXerna TherapeuticsOncXerna Therapeutics offers precision medicine using an innovative RNA-based biomarker platform.OncXerna Therapeutics offers precision medicine using an innovative RNA-based biomarker platform.
Founded 2018Waltham, United States$30Mlast round Mar 2022 - 31
EnvisagenicsEnvisagenics is an AI-driven biotechnology company founded in 2014, focusing on the discovery and development of novel RNA splicing therapeutics for oncology anEnvisagenics is an AI-driven biotechnology company founded in 2014, focusing on the discovery and development of novel RNA splicing therapeutics for oncology an
Founded 2014New York, United States$27Mlast round Jun 2024 - 32
Transcode TherapeuticsTransCode Therapeutics is an RNA oncology company that develops and commercializes drugs for the treatment of metastatic cancer.TransCode Therapeutics is an RNA oncology company that develops and commercializes drugs for the treatment of metastatic cancer.
Founded 2016Newton, United States$26Mlast round Apr 2026 - 33
Rona TherapeuticsRona Therapeutics is a biotechnology company based in Shanghai, China, founded in 2021.Rona Therapeutics is a biotechnology company based in Shanghai, China, founded in 2021.
Founded 2021Shanghai, China$25Mlast round Mar 2025 - 34
Eleven TherapeuticsEleven Therapeutics is a biotechnology company founded in 2020, specializing in next-generation RNA therapeutics.Eleven Therapeutics is a biotechnology company founded in 2020, specializing in next-generation RNA therapeutics.
Founded 2020Cambridge, United Kingdom$22Mlast round Aug 2022 - 35
Tacit TherapeuticsTacit Therapeutics created RNA-targeting treatments for devastating diseases.Tacit Therapeutics created RNA-targeting treatments for devastating diseases.
Founded 2021South San Francisco, United States$19Mlast round Mar 2026 - 36
Innovac TherapeuticsInnovac Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2022.Innovac Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2022.
Founded -Cambridge, United States$18Mlast round Sept 2023 - 37
OligonOligon Therapeutics Inc.Oligon Therapeutics Inc.
Founded -Montreal, United States$14Mlast round Sept 2025 - 38StemirnaStemirna Therapeutics is a RNA technology based drug development company designed to maximize the potential of RNA science.
Stemirna Therapeutics is a RNA technology based drug development company designed to maximize the potential of RNA science.
Founded -China$14Mlast round May 2023 - 39
Vico TherapeuticsVico Therapeutics is a clinical-stage genetic medicines company based in Leiden, the Netherlands.Vico Therapeutics is a clinical-stage genetic medicines company based in Leiden, the Netherlands.
Founded 2019Leiden, Netherlands$12Mlast round Jun 2024 - 40
Therna BiosciencesTherna Biosciences is a biotechnology company based in San Francisco, founded in 2023.Therna Biosciences is a biotechnology company based in San Francisco, founded in 2023.
Founded 2025San Francisco, United States$10Mlast round Aug 2025 - 41
Amaroq TherapeuticsAmaroq Therapeutics is a biotechnology company based in New Zealand that focuses on developing innovative cancer therapeutics targeting long non-coding RNAs (lncRNAs).Amaroq Therapeutics is a biotechnology company based in New Zealand that focuses on developing innovative cancer therapeutics targeting long non-coding RNAs (lncRNAs).
Founded 2021Auckland, New Zealand$9.7Mlast round Jul 2021 - 42
Terrain BioTerrain BioSciences accelerates RNA-based therapeutics and vaccine development using AI and proprietary platforms.Terrain BioSciences accelerates RNA-based therapeutics and vaccine development using AI and proprietary platforms.
Founded -Cambridge, United States$9.0Mlast round Feb 2025 - 43
Heqet TherapeuticsHeqet Therapeutics is a pre-clinical stage biotechnology company based in Turin, Italy.Heqet Therapeutics is a pre-clinical stage biotechnology company based in Turin, Italy.
Founded -Deerfield, United Kingdom$8.8Mlast round Mar 2022 - 44
Expansion TherapeuticsExpansion Therapeutics is a biotechnology company based in Boston, focused on developing oral medicines for severe RNA-mediated diseases, particularly neurodegeExpansion Therapeutics is a biotechnology company based in Boston, focused on developing oral medicines for severe RNA-mediated diseases, particularly neurodege
Founded 2016Jupiter, United States$6.9Mlast round Jan 2023 - 45
Crucible TherapeuticsCrucible Therapeutics is a biotechnology company based in Sheffield, England, founded in 2023.Crucible Therapeutics is a biotechnology company based in Sheffield, England, founded in 2023.
Founded 2023United Kingdom$6.3Mlast round Mar 2025 - 46
pHion TherapeuticspHion Therapeutics is a biopharmaceutical company based in Belfast, Northern Ireland, focused on developing therapeutic and prophylactic mRNA vaccines.pHion Therapeutics is a biopharmaceutical company based in Belfast, Northern Ireland, focused on developing therapeutic and prophylactic mRNA vaccines.
Founded 2017Belfast, United Kingdom$6.2Mlast round Jun 2023 - 47
HDT BioHDT Bio is a developer of RNA vaccines and therapeutics based on LION formulation technology.HDT Bio is a developer of RNA vaccines and therapeutics based on LION formulation technology.
Founded 2018Seattle, United States$6.2Mlast round Sept 2026 - 48
XFOREST TherapeuticsXFOREST Therapeutics is a biotech company focused on drug discovery using RNA structures.XFOREST Therapeutics is a biotech company focused on drug discovery using RNA structures.
Founded -Kyoto, Japan$6.1Mlast round Jan 2025 - 49
CamGene TherapeuticsCamGene Therapeutics is a biotechnology company based in Cambridge, UK, focused on developing RNA-based gene medicines specifically for hearing loss.CamGene Therapeutics is a biotechnology company based in Cambridge, UK, focused on developing RNA-based gene medicines specifically for hearing loss.
Founded 2024Cambridge, United Kingdom$5.4Mlast round May 2026 - 50
ReviR TherapeuticsReviR Therapeutics is a genomics-based platform that develops novel medicines targeting human RNAs.ReviR Therapeutics is a genomics-based platform that develops novel medicines targeting human RNAs.
Founded 2021Brisbane, United States$4.6Mlast round Apr 2026
Cambridge, United Kingdom
Cambridge, United States
Leiden, Netherlands
Dublin, Ireland
Suzhou, China
Paterna, Spain
Juelich, Germany
Auckland, New Zealand
Kyoto, JapanCompanies whose own description names this theme, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
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