Top list · United States
Pharma startups in the United States
540 pharma startups in the United States have raised money in rounds we track. These are the 50 that have raised the most, $23B between them, with New York the most common home.
- 1
Altos LabsAltos Labs focuses on cellular rejuvenation programming to restore cell health and resilience, to reverse disease to transform medicine.Altos Labs focuses on cellular rejuvenation programming to restore cell health and resilience, to reverse disease to transform medicine.
Founded 2021San Francisco, United States$3.0Blast round Sept 2021 - 2National ResilienceFounded 2020United States$1.6Blast round Jul 2026
- 3
Retro BiosciencesRetro Biosciences is a biotechnology company based in Redwood City, California, founded in May 2021.Retro Biosciences is a biotechnology company based in Redwood City, California, founded in May 2021.
Founded 2021Redwood City, United States$1.2Blast round May 2026 - 4
ResilienceResilience is a cyber risk company based in San Francisco, founded in 2016 by experts from military intelligence, insurance, and technology.Resilience is a cyber risk company based in San Francisco, founded in 2016 by experts from military intelligence, insurance, and technology.
Founded 2016New York, United States$860Mlast round Oct 2025 - 5
Mineralys TherapeuticsMineralys Therapeutics is a clinical-stage biopharmaceutical company committed to developing therapy for the treatment of hypertension.Mineralys Therapeutics is a clinical-stage biopharmaceutical company committed to developing therapy for the treatment of hypertension.
Founded 2019Radnor, United States$788Mlast round Jun 2026 - 6
Dianthus TherapeuticsDianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach.Dianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach.
Founded 2019Waltham, United States$719Mlast round Mar 2026 - 7
VaxcyteVaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.
Founded 2013San Carlos, United States$633Mlast round Jan 2026 - 8
Axsome TherapeuticsAxsome Therapeutics is a biopharmaceutical company that develops therapies for the management and treatment of neurological disorders.Axsome Therapeutics is a biopharmaceutical company that develops therapies for the management and treatment of neurological disorders.
Founded 2012New York, United States$577Mlast round May 2025 - 9
CRISPR THERAPEUTICSCRISPR Therapeutics is focused on the development of transformative medicines using its proprietary CRISPR/Cas9 gene-editing platform.CRISPR Therapeutics is focused on the development of transformative medicines using its proprietary CRISPR/Cas9 gene-editing platform.
Founded 2014United States$550Mlast round Mar 2026 - 10
ImmunovantImmunovant is a clinical-stage biopharmaceutical company focused on enabling normal lives for patients with autoimmune diseases.Immunovant is a clinical-stage biopharmaceutical company focused on enabling normal lives for patients with autoimmune diseases.
Founded 2018New York, United States$550Mlast round Dec 2025 - 11
Korsana BiosciencesKorsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s.Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s.
Founded -Waltham, United States$530Mlast round Sept 2026 - 12
MapLight TherapeuticsMapLight Therapeutics is a biopharma company that offers a platform designed to discover and develop therapeutics for brain disorders.MapLight Therapeutics is a biopharma company that offers a platform designed to discover and develop therapeutics for brain disorders.
Founded 2018Palo Alto, United States$523Mlast round Aug 2026 - 13
Ollin BiosciencesOllin Biosciences is a clinical-stage biopharmaceutical company based in Austin, Texas, founded in 2023.Ollin Biosciences is a clinical-stage biopharmaceutical company based in Austin, Texas, founded in 2023.
Founded -Austin, United States$430Mlast round Jun 2026 - 14
Remedi SeniorCareRemedi SeniorCare provides pharmacy services by offering automatic therapeutic interchange education and consulting and transition services.Remedi SeniorCare provides pharmacy services by offering automatic therapeutic interchange education and consulting and transition services.
Founded 1954Baltimore, United States$430Mlast round Aug 2013 - 15
Arcus BiosciencesArcus Biosciences is a biopharmaceutical company that discovers, develops, and commercializes novel therapies for the treatment of cancer.Arcus Biosciences is a biopharmaceutical company that discovers, develops, and commercializes novel therapies for the treatment of cancer.
Founded 2015Hayward, United States$427Mlast round Oct 2025 - 16
Zenas BioPharmaZenas BioPharma is a biopharmaceutical company that focuses on developing immune-based therapies for patients.Zenas BioPharma is a biopharmaceutical company that focuses on developing immune-based therapies for patients.
Founded 2023Waltham, United States$420Mlast round Mar 2026 - 17
SpringWorks TherapeuticsSpringWorks Therapeutics is a biopharmaceutical company that develops medicines for patients with severe rare diseases and cancer.SpringWorks Therapeutics is a biopharmaceutical company that develops medicines for patients with severe rare diseases and cancer.
Founded 2017Stamford, United States$400Mlast round Dec 2023 - 18
Parabilis MedicinesParabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines.Parabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines.
Founded -Cambridge, United States$380Mlast round Jun 2026 - 19
Madrigal PharmaceuticalsMadrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases.Madrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases.
Founded 2011Conshohocken, United States$350Mlast round Jul 2025 - 20
89Bio89bio is a biopharmaceutical company that develops clinical-stage therapies for liver and cardiometabolic diseases.89bio is a biopharmaceutical company that develops clinical-stage therapies for liver and cardiometabolic diseases.
Founded 2018San Francisco, United States$348Mlast round Jan 2025 - 21Crystalys TherapeuticsFounded -United States$335Mlast round Jul 2026
- 22
NGM BiopharmaceuticalsNGM Biopharmaceuticals Inc.NGM Biopharmaceuticals Inc.
Founded 2008South San Francisco, United States$333Mlast round Mar 2015 - 23eGenesisFounded -United States$329Mlast round Sept 2024
- 24
Corvus PharmaceuticalsCorvus Pharmaceuticals is a clinical-stage biopharmaceutical company.
Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company.
Founded 2014Burlingame, United States$310Mlast round Jan 2026 - 25
Maze TherapeuticsMaze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines.Maze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines.
Founded 2018South San Francisco, United States$300Mlast round Apr 2026 - 26
Beeline MedicinesBeeline Medicines is a clinical-stage biotechnology company based in Boston, Massachusetts, focused on developing precision therapies for autoimmune and inflammBeeline Medicines is a clinical-stage biotechnology company based in Boston, Massachusetts, focused on developing precision therapies for autoimmune and inflamm
Founded 2025Stamford, United States$300Mlast round Apr 2026 - 27
ACELYRINACELYRIN is a biopharma company that identifies, acquires, and accelerates the development and commercialization of life-changing therapies.
ACELYRIN is a biopharma company that identifies, acquires, and accelerates the development and commercialization of life-changing therapies.
Founded 2020Los Angeles, United States$300Mlast round Sept 2022 - 28
AllakosAllakos is a biotechnology company developing therapeutic antibodies targeting allergy, inflammatory and proliferative diseases.Allakos is a biotechnology company developing therapeutic antibodies targeting allergy, inflammatory and proliferative diseases.
Founded 2012Redwood City, United States$294Mlast round Sept 2022 - 29
ArcellxArcellx is a clinical-stage biotechnology company focused on developing innovative immunotherapies for cancer and other incurable diseases.Arcellx is a clinical-stage biotechnology company focused on developing innovative immunotherapies for cancer and other incurable diseases.
Founded 2015Redwood City, United States$285Mlast round Nov 2023 - 30
Cullinan TherapeuticsCullinan Therapeutics is a developer of an externally sourced cancer therapeutics used to end a drug program quickly.Cullinan Therapeutics is a developer of an externally sourced cancer therapeutics used to end a drug program quickly.
Founded -Cambridge, United States$280Mlast round Apr 2024 - 31
Emalex BiosciencesEmalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders.Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders.
Founded 2018Chicago, United States$270Mlast round Nov 2022 - 32InhibrxFounded 2017United States$265Mlast round Mar 2026
- 33
Capital RxCapital Rx, now rebranded as Judi Health, is a prominent enterprise health technology company specializing in pharmacy benefits management (PBM).Capital Rx, now rebranded as Judi Health, is a prominent enterprise health technology company specializing in pharmacy benefits management (PBM).
Founded 2017New York, United States$264Mlast round Sept 2025 - 34
Compass TherapeuticsCompass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.
Founded 2014Boston, United States$257Mlast round Aug 2025 - 35
KardiganKardigan is a heart health company developing drugs designed to make cardiovascular disease curable, preventable, and no longer the leading cause of death.Kardigan is a heart health company developing drugs designed to make cardiovascular disease curable, preventable, and no longer the leading cause of death.
Founded 2023Princeton, United States$254Mlast round Oct 2025 - 36
LB PharmaceuticalsLB Pharmaceuticals specializes in developing a treatment for schizophrenia.LB Pharmaceuticals specializes in developing a treatment for schizophrenia.
Founded 2015Menlo Park, United States$250Mlast round Jul 2026 - 37
ORIC PharmaceuticalsORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance.ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance.
Founded 2014South San Francisco, United States$248Mlast round May 2025 - 38
Harmony BiosciencesHarmony Biosciences is a pharmaceutical company that develops and commercializes novel therapies for rare neurological disorders.Harmony Biosciences is a pharmaceutical company that develops and commercializes novel therapies for rare neurological disorders.
Founded 2017Plymouth Meeting, United States$248Mlast round Oct 2024 - 39
Arcutis BiotherapeuticsArcutis Biotherapeutics is a clinical-stage biopharmaceutical company focused on developing medical dermatology for unmet needs.Arcutis Biotherapeutics is a clinical-stage biopharmaceutical company focused on developing medical dermatology for unmet needs.
Founded 2016Westlake Village, United States$245Mlast round Feb 2024 - 40Aiolos BioAiolos Bio is a biotech company developing innovative therapies for respiratory diseases and immune conditions.
Aiolos Bio is a biotech company developing innovative therapies for respiratory diseases and immune conditions.
Founded 2023London, United States$245Mlast round Oct 2023 - 41
OmniOmni Metalcraft provides conveyors, replacement rollers, and components to manufacturing industries.Omni Metalcraft provides conveyors, replacement rollers, and components to manufacturing industries.
Founded 1976Alpena, United States$244Mlast round Nov 2026 - 42
Seaport TherapeuticsSeaport Therapeutics operates as a clinical stage biopharmaceutical company.Seaport Therapeutics operates as a clinical stage biopharmaceutical company.
Founded 2024Boston, United States$240Mlast round Mar 2026 - 43
Zentalis PharmaceuticalsZentalis is a pharmaceutical company focused on developing clinical therapeutics for cancer patients.Zentalis is a pharmaceutical company focused on developing clinical therapeutics for cancer patients.
Founded -New York, United States$236Mlast round Jun 2023 - 44City TherapeuticsFounded -United States$235Mlast round Jun 2026
- 45
Roivant SciencesRoivant aims to improve health by rapidly delivering innovative medicines and technologies to patients.Roivant aims to improve health by rapidly delivering innovative medicines and technologies to patients.
Founded -United States$230Mlast round Feb 2023 - 46
Solstice OncologySolstice Oncology develops immuno-oncology therapies focused on treating and preventing cancer through targeted approaches.Solstice Oncology develops immuno-oncology therapies focused on treating and preventing cancer through targeted approaches.
Founded -Boston, United States$225Mlast round Sept 2026 - 47
moksha8 PharmaceuticalsMoksha8 is a pharmaceutical company providing therapeutics for the treatment of central nervous system and mental health disorders.Moksha8 is a pharmaceutical company providing therapeutics for the treatment of central nervous system and mental health disorders.
Founded 2007Berwyn, United States$224Mlast round Oct 2012 - 48
Matchpoint TherapeuticsMatchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.Matchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.
Founded 2021Cambridge, United States$220Mlast round Oct 2026 - 49
Poseida TherapeuticsPoseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics.Poseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics.
Founded 2014San Diego, United States$217Mlast round Aug 2023 - 50
MetseraMetsera operates as a clinical-stage biopharmaceutical company.Metsera operates as a clinical-stage biopharmaceutical company.
Founded 2022New York City, United States$215Mlast round Nov 2024
San Francisco, United StatesCompanies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
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