Top list · United States
DeFi startups in the United States
29 DeFi startups in the United States have raised money in rounds we track. These are the 29 that have raised the most, $1.5B between them, with New York the most common home.
- 1
Digital AssetDigital Asset develops ledger technology intended to build distributed, encrypted straight-through processing tools.Digital Asset develops ledger technology intended to build distributed, encrypted straight-through processing tools.
Founded 2014New York, United States$580Mlast round Jun 2026 - 2
Flying TulipFlying Tulip is an on-chain financial marketplace and decentralized exchange based in San Francisco, California, with operations also noted in New York City.Flying Tulip is an on-chain financial marketplace and decentralized exchange based in San Francisco, California, with operations also noted in New York City.
Founded 2024New York, United States$226Mlast round Jan 2026 - 3
GauntletGauntlet is a financial technology and quantitative research firm focused on decentralized finance (DeFi) risk management, economic modeling, and protocol optimization.Gauntlet is a financial technology and quantitative research firm focused on decentralized finance (DeFi) risk management, economic modeling, and protocol optimization.
Founded 2018New York, United States$125Mlast round Jul 2026 - 4
Supersetsuper{set} is a team of seasoned operators and AI technologists that co-founds and builds AI-native, high potential businesses.super{set} is a team of seasoned operators and AI technologists that co-founds and builds AI-native, high potential businesses.
Founded -United States$81Mlast round Aug 2026 - 5
n3xtN3XT is a full-reserve bank based in Cheyenne, Wyoming, specializing in instant, programmable business-to-business (B2B) payments in U.S.N3XT is a full-reserve bank based in Cheyenne, Wyoming, specializing in instant, programmable business-to-business (B2B) payments in U.S.
Founded 2023Cheyenne, United States$72Mlast round Oct 2025 - 6
LighterLighter provides software and services to bridge the gap between dietary recommendations and people's eating habits.Lighter provides software and services to bridge the gap between dietary recommendations and people's eating habits.
Founded 2014Cambridge, United States$68Mlast round Nov 2025 - 7
Jito LabsJito Labs is a leading infrastructure provider for the Solana blockchain, focusing on low-latency Maximal Extractable Value (MEV) solutions.Jito Labs is a leading infrastructure provider for the Solana blockchain, focusing on low-latency Maximal Extractable Value (MEV) solutions.
Founded 2021Arlington, United States$60Mlast round Oct 2025 - 8
PharosPharos is an AI-powered healthcare startup founded in 2024 that focuses on automating hospital quality reporting.Pharos is an AI-powered healthcare startup founded in 2024 that focuses on automating hospital quality reporting.
Founded -San Francisco, United States$49Mlast round Apr 2026 - 9
LimitlessLimitless Technology is an integrated e-commerce group with a track record of launching, scaling, and acquiring profitable e-brands.Limitless Technology is an integrated e-commerce group with a track record of launching, scaling, and acquiring profitable e-brands.
Founded 2016Melbourne, United States$32Mlast round Jul 2025 - 10
OstiumOstium Labs, Co.Ostium Labs, Co.
Founded -London, United States$24Mlast round Dec 2025 - 11
HeliosFounded -United States$20Mlast round Sept 2026 - 12
aPrioriApriori is an international data aggregator.Apriori is an international data aggregator.
Founded 2014McLean, United States$20Mlast round Sept 2025 - 13
MagnaMagna develops a token vesting and DeFi investment management platform.Magna develops a token vesting and DeFi investment management platform.
Founded 2022San Francisco, United States$15Mlast round Sept 2022 - 14
CambrianInvesting $250k to $1mm+ at pre-seed / seed stages to fuel fintech’s next evolution.Investing $250k to $1mm+ at pre-seed / seed stages to fuel fintech’s next evolution.
Founded -United States$12Mlast round Jun 2026 - 15
Block StreetBlockstreet is a resource for non-technical individuals or corporations that are seeking to learn more about Blockchain technology and Cryptocurrencies.Blockstreet is a resource for non-technical individuals or corporations that are seeking to learn more about Blockchain technology and Cryptocurrencies.
Founded 2017Lowell, United States$12Mlast round Oct 2025 - 16
Stewards IncStewards, Inc.Stewards, Inc.
Founded -Bakersfield, United States$10Mlast round Nov 2025 - 17
Ethos NetworkThe Ethos Credibility Score is the first dApp created on the Ethos Network.The Ethos Credibility Score is the first dApp created on the Ethos Network.
Founded 2023Austin, United States$8.4Mlast round Sept 2026 - 18
StratosStratos merges the efficiency and familiarity of a conventional payment card with the power and convenience of a mobile wallet.Stratos merges the efficiency and familiarity of a conventional payment card with the power and convenience of a mobile wallet.
Founded 2012United States$5.8Mlast round Oct 2014 - 19
Cork ProtocolCork Protocol is a DeFi risk infrastructure protocol that focuses on tokenizing and managing depeg risks for pegged assets such as stablecoins and liquid staking tokens.Cork Protocol is a DeFi risk infrastructure protocol that focuses on tokenizing and managing depeg risks for pegged assets such as stablecoins and liquid staking tokens.
Founded 2023New York, United States$5.5Mlast round Jan 2026 - 20
TBookTBook is the first embedded RWA liquidity layer that brings institutional-grade tokenized yield into user-facing apps.TBook is the first embedded RWA liquidity layer that brings institutional-grade tokenized yield into user-facing apps.
Founded 2023New York, United States$5.0Mlast round Jan 2026 - 21
Swivel FinanceSwivel Finance is a decentralized finance protocol that specializes in fixed-rate lending and interest-rate derivatives.Swivel Finance is a decentralized finance protocol that specializes in fixed-rate lending and interest-rate derivatives.
Founded 2020Valley Park, United States$4.7Mlast round Oct 2021 - 22
BlackwingBlackwing is a crypto and DeFi company that focuses on building a modular blockchain and a decentralized exchange (DEX) abstraction layer.Blackwing is a crypto and DeFi company that focuses on building a modular blockchain and a decentralized exchange (DEX) abstraction layer.
Founded 2023New York, United States$4.5Mlast round Mar 2024 - 23
0xbow0xbow is a Nashville-based cryptocurrency infrastructure company founded in 2023.0xbow is a Nashville-based cryptocurrency infrastructure company founded in 2023.
Founded 2023Nashville, United States$3.5Mlast round Nov 2025 - 24bboxbbox offers professional trading on the Decentralized Perpetual Exchange and hybrid markets.
bbox offers professional trading on the Decentralized Perpetual Exchange and hybrid markets.
Founded -Miami, United States$2.7Mlast round Jan 2024 - 25
MultisynqMultisynq is a decentralized synchronization layer that lets people, AI agents, and machines create, connect, and coordinate in real time without centralized inMultisynq is a decentralized synchronization layer that lets people, AI agents, and machines create, connect, and coordinate in real time without centralized in
Founded 2023Los Angeles, United States$2.2Mlast round Apr 2024 - 26
We.RichWe.Rich operates as a User Generated Assets(UGA) platform.We.Rich operates as a User Generated Assets(UGA) platform.
Founded -New York, United States$2.0Mlast round Jul 2024 - 27
HyloHylo is a web and mobile app that combines group management, messaging and collaboration - all in one place.Hylo is a web and mobile app that combines group management, messaging and collaboration - all in one place.
Founded 2012Oakland, United States$1.5Mlast round Aug 2025 - 28
Candlestick.ioCandlestick.io offers visualizations of the financial market, providing a way for users to analyze and interpret market trends.Candlestick.io offers visualizations of the financial market, providing a way for users to analyze and interpret market trends.
Founded -San Mateo, United States$1.2Mlast round Dec 2023 - 29
MetaphoneMetaphone is a decentralized marketing network offers transparent, safe, and effective marketing services.Metaphone is a decentralized marketing network offers transparent, safe, and effective marketing services.
Founded 2024San Francisco, United States$1.0Mlast round May 2024
New York, United StatesCompanies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
Who backed them?
Open any company for its rounds and investors, or search the investors who back DeFi startups in the United States in the app, with filters, lists and exports.
More defi lists
See all
M
DMore lists for United States
See all
O
A
XStartups in the United States42,176 companies · $870B
GV
V
RPHealth startups in the United States7,411 companies · $71BOAXAI startups in the United States5,656 companies · $718BVRP
DHHealthcare startups in the United States4,148 companies · $51B
S
P
IIT Services startups in the United States3,482 companies · $27B
D
CE
ADBig Data & Analytics startups in the United States2,107 companies · $132BOA
WAI startups in the United States that raised in 20261,648 companies · $431B in 2026D
P
ASoftware startups in the United States1,638 companies · $77B