Top list · Worldwide
154 chronic disease startups worldwide have raised money in rounds we track. These are the 50 that have raised the most, $7.3B between them, with the United States the most common home.
Intarcia Therapeutics develops therapies for diseases that require long-term chronic treatment.
Founded 1997Boston, United States$1.1Blast round Sept 2016Oruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases.
Founded -Waltham, United States$880Mlast round Apr 2026Strive Health is a healthcare technology company based in Denver, Colorado, focused on value-based kidney care.
Founded 2018Denver, United States$440Mlast round Sept 2025Tubulis is a chemotherapeutic medication developer specializing in cancer and chronic disease treatment.
Founded 2012Munich, Germany$401Mlast round Oct 2025Dice Therapeutics is a clinical-stage biopharmaceutical company that makes medicines for chronic autoimmune and inflammatory diseases.
Founded 2013San Francisco, United States$345Mlast round Oct 2022Liberty Dialysis affiliates, develops and operates dialysis clinics and offers chronic kidney disease outreach and home dialysis programs.
Founded 2002Mercer Island, United States$340Mlast round Jul 2010Morphic Therapeutic is a biotechnology company that develops oral integrin therapies to treat serious chronic diseases.
Founded 2015Waltham, United States$328Mlast round May 2023Expedition Therapeutics is a biotechnology company based in San Francisco, founded in 2024.
Founded 2024San Francisco, United States$280Mlast round Aug 2026Samay Health, founded in 2018 by Dr.
Founded 2019Mountain View, United States$250Mlast round May 2026Aviceda Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2018.
Founded 2018Cambridge, United States$208Mlast round Jan 2025AirNexis Therapeutics develops clinical-stage therapies for chronic obstructive pulmonary disease and other pulmonary conditions.
Founded -Palo Alto, United States$200Mlast round Jan 2026Resolution Therapeutics is a biopharmaceutical company developing macrophage cell therapy to treat chronic diseases.
Founded 2017London, United Kingdom$159Mlast round May 2026Cala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013.
Founded 2014San Mateo, United States$150Mlast round Apr 2026Prokidney provide specialized treatment for chronic kidney disease.
Founded -Salem, United States$140Mlast round Jun 2024Apreo Health is a clinical-stage medical device company based in Menlo Park, California, founded in 2021.
Founded -Menlo Park, United States$130Mlast round May 2026Galvanize Therapeutics is a commercial-stage medical technology company based in San Carlos, California.
Founded 2015Redwood City, United States$125Mlast round Jan 2019Ouro Medicines is a biotechnology company based in South San Francisco, established in 2025 by Monograph Capital in partnership with GSK.
Founded 2024San Francisco, United States$120Mlast round Jan 2025Pathalys Pharma is a private biopharmaceutical company based in Raleigh, North Carolina, founded in 2021.
Founded 2021Raleigh, United States$105Mlast round Aug 2024Virtue Diagnostics is a global in vitro diagnostics (IVD) company founded in 2019, with a focus on providing affordable and precise clinical solutions for infec
Founded 2019Singapore, Singapore$100Mlast round Jan 2022Mironid is a drug discovery company focused on therapeutics for degenerative kidney diseases, chronic inflammatory diseases, and cancer.
Founded 2014Glasgow, United Kingdom$99Mlast round Aug 2026Calluna Pharma is a clinical-stage biotechnology company based in Oslo, Norway.
Founded 2024Oslo, Norway$81Mlast round Jan 2024Viome is a systems biology company founded in 2016, dedicated to analyzing individual biology at a molecular level.
Founded 2016Bellevue, United States$71Mlast round Sept 2024Propeller Health, now operating as Reciprocal Labs Corporation under ResMed, was a digital therapeutics company founded in 2010.
Founded 2010San Diego, United States$70Mlast round May 2018Cagent Vascular is a medical device company based in Wayne, Pennsylvania, focused on advancing treatment for Peripheral Artery Disease (PAD) and Chronic Limb-Th
Founded 2014Wayne, United States$68Mlast round May 2026Inotrem is a French biotechnology company founded in 2013, based in Paris with a technology center in Nancy.
Founded 2013Paris, France$66Mlast round Nov 2023Developing disease specific immune therapies to treat severe, chronic auto-immune, inflammatory, allergic, infectious diseases and tumors.
Founded 2010Liege, Belgium$65Mlast round Feb 2021Gold Kidney Health Plan is a Medicare Advantage organization that specializes in Chronic Special Needs Plans (C-SNPs) for individuals with end-stage renal disea
Founded 2021Portsmouth, United States$60Mlast round Dec 2022Twin Health is a HealthTech company founded in 2018 and based in Mountain View, California, with operations in Chennai, India.
Founded 2018Menlo Park, United States$59Mlast round Sept 2026Medopad, now known as Huma, is a global health technology company founded in 2011 and based in London, with additional offices in the US and China.
Founded 2011London, United Kingdom$54Mlast round Nov 2019Endpoint Health is a precision-medicine therapeutics company based in Palo Alto, California, founded in 2018.
Founded 2018Palo Alto, United States$52Mlast round Jun 2022Montai Therapeutics is a biotechnology company based in Cambridge, MA, founded in 2022.
Founded 2022Cambridge, United States$50Mlast round Dec 2022HealthSnap is a virtual care management platform for chronic disease management.
Founded 2015Miami, United States$50Mlast round Aug 2026Novome Biotechnologies is a clinical-stage biotechnology company located in South San Francisco, California.
Founded 2016South San Francisco, United States$44Mlast round Sept 2022Arda Therapeutics is a biotechnology company based in the San Francisco Bay Area, founded in 2021.
Founded 2021San Carlos, United States$43Mlast round Oct 2024Symic Bio is a biopharmaceutical company based in San Francisco, California, founded in 2012.
Founded 2012San Francisco, United States$41Mlast round Apr 2019Juventas is a biotechnology company that discovers and develops non-viral gene therapies for the treatment of chronic cardiovascular diseases.
Founded 2007Cleveland, United States$41Mlast round May 2015Curve Biosciences is a biotechnology company based in San Mateo, California, founded in 2021.
Founded 2021Dallas, United States$40Mlast round Oct 2025Holmusk is a provider of healthcare data and technology solutions to support the treatment of mental health and chronic diseases.
Founded 2015Singapore, Singapore$40Mlast round Oct 2023HealthReveal provides a cloud-based clinical analytics platform designed to preempt the avoidable consequences of chronic disease.
Founded 2015New York, United States$37Mlast round Dec 2019Scioderm, a clinical stage pharmaceutical company, develops topical products for the treatment of chronic skin diseases.
Founded 2012Durham, United States$37Mlast round Dec 2014Virta Health is a technology-enabled telehealth company focused on reversing chronic metabolic diseases, particularly Type 2 diabetes and obesity, without medic
Founded 2014Denver, United States$37Mlast round Mar 2017mbiomics GmbH is a biotechnology company based in Munich, Germany, founded in 2020 by Laura Figulla, Markus Rinecker, and Johannes Wöhrstein.
Founded 2020Neuried, Germany$35Mlast round May 2026HepaRegeniX is developing drugs for treating acute and chronic liver diseases.
Founded 2015Tuebingen, Germany$34Mlast round Apr 2025Longeveron is a biotechnology company that focuses on developing cellular therapies for chronic aging-related and life-threatening diseases.
Founded 2014Miami, United States$30Mlast round Mar 2026Ochre Bio is a biotechnology company based in Oxford, United Kingdom, founded in 2019.
Founded 2019Oxford, United Kingdom$30Mlast round Oct 2022Alcresta develops enzyme-based nutritional products for infants and adults with acute and chronic diseases.
Founded 2011Newton, United States$30Mlast round Feb 2020Istesso is a London-based biopharmaceutical company focused on immunometabolism drug discovery and development.
Founded 2017London, United Kingdom$29Mlast round Apr 2023AbolerIS Pharma is a Belgian clinical-stage biopharmaceutical company founded in November 2019.
Founded 2019Charleroi, France$29Mlast round Sept 2023SpyGlass is a California-based ophthalmic therapeutics company that researches and develops novel treatments for chronic ophthalmic diseases.
Founded 2019Mission Viejo, United States$28Mlast round Jan 2021Wellinks is a digital health company based in New Haven, Connecticut, focused on enhancing cardiopulmonary care, particularly for individuals with Chronic Obstr
Founded 2014New Haven, United States$25Mlast round Nov 2021Companies whose own description names this theme, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
Open any company for its rounds and investors, or search the investors who back chronic disease startups worldwide in the app, with filters, lists and exports.
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RPHealth startups worldwide12,811 companies · $81B
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XAI startups worldwide10,238 companies · $830B
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RPBiotech startups worldwide7,127 companies · $70B
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FTBig data startups worldwide3,812 companies · $220BAF
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SFintech startups worldwide3,200 companies · $94B
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BAI startups that raised in 20262,922 companies · $540B in 2026
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PEnergy providers startups worldwide2,808 companies · $152B
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OMarketing tech startups worldwide2,728 companies · $28B