Top list · United States

Chemicals and materials startups in the United States

277 chemicals and materials startups in the United States have raised money in rounds we track. These are the 50 that have raised the most, $11B between them, with San Francisco the most common home.

$11Braised by these 50
277on our record in all
San Franciscomost common home
USA Rare Earthraised the most
  1. 1USA Rare EarthUSA Rare Earth is a mining and advanced materials company that produces critical minerals and permanent magnets.

    USA Rare Earth is a mining and advanced materials company that produces critical minerals and permanent magnets.

    Founded 2019Stillwater, United States$2.7Blast round Sept 2026
  2. 2MirendilMirendil is an AI research lab that creates self-accelerating systems that convert computing power into scientific advancements.

    Mirendil is an AI research lab that creates self-accelerating systems that convert computing power into scientific advancements.

    Founded -San Francisco, United States$1.4Blast round Nov 2026
  3. 3Redwood MaterialsRedwood Materials is an American company based in Carson City, Nevada, focused on creating a sustainable supply chain for lithium-ion batteries.

    Redwood Materials is an American company based in Carson City, Nevada, focused on creating a sustainable supply chain for lithium-ion batteries.

    Founded 2017Carson City, United States$1.2Blast round Jan 2026
  4. 4CSW IndustrialsCSW Industrials is a diversified industrial growth company with well-established, scalable platforms and domain expertise.

    CSW Industrials is a diversified industrial growth company with well-established, scalable platforms and domain expertise.

    Founded 2015Dallas, United States$700Mlast round May 2025
  5. 5ChemoursThe Chemours Company, commonly referred to as Chemours, is an American chemical company

    The Chemours Company, commonly referred to as Chemours, is an American chemical company

    Founded -Wilmington, United States$700Mlast round Feb 2026
  6. 6Group14 TechnologiesGroup14 Technologies is a leading manufacturer of advanced silicon battery materials, based in Woodinville, Washington.

    Group14 Technologies is a leading manufacturer of advanced silicon battery materials, based in Woodinville, Washington.

    Founded 2015Woodinville, United States$632Mlast round Oct 2026
  7. 7Phoenix TailingsFounded to bring a new level of sustainability and efficiency to the mining industry by enabling new sources of primary metals.

    Founded to bring a new level of sustainability and efficiency to the mining industry by enabling new sources of primary metals.

    Founded 2019Woburn, United States$530Mlast round Jun 2026
  8. 8CirculusCirculus, based in Plano, Texas, specializes in accounts payable (AP) automation and business process outsourcing (BPO) solutions.

    Circulus, based in Plano, Texas, specializes in accounts payable (AP) automation and business process outsourcing (BPO) solutions.

    Founded 1998Plano, United States$300Mlast round Oct 2022
  9. 9Principal MineralPrincipal Mineral is a Dallas-based company focused on developing and scaling domestic production of strategic metals, high-performance alloys, and advanced materials.

    Principal Mineral is a Dallas-based company focused on developing and scaling domestic production of strategic metals, high-performance alloys, and advanced materials.

    Founded 2024Dallas, United States$280Mlast round Jun 2026
  10. 10TemperPackTemperPack manufactures insulated packaging solutions that meet the needs of all industries that ship perishable items.

    TemperPack manufactures insulated packaging solutions that meet the needs of all industries that ship perishable items.

    Founded 2015Richmond, United States$208Mlast round Mar 2022
  11. 11MycoTechnologyMycoTechnology utilizes fungi-based food-processing platforms to transform the flavor and value of agricultural products.

    MycoTechnology utilizes fungi-based food-processing platforms to transform the flavor and value of agricultural products.

    Founded 2013Aurora, United States$203Mlast round Mar 2022
  12. 12NatureWorksNatureWorks, a cleantech company, manufactures low carbon footprint biopolymers from renewable resources.

    NatureWorks, a cleantech company, manufactures low carbon footprint biopolymers from renewable resources.

    Founded 1997Plymouth, United States$150Mlast round Oct 2011
  13. 13TrinseoTrinseo, formerly known as Styron until February 2015

    Trinseo, formerly known as Styron until February 2015

    Founded 2010Berwyn, United States$150Mlast round Jul 2024
  14. 14Mesabi MetallicsFounded -United States$150Mlast round Apr 2026
  15. 15Gold.comFounded -United States$150Mlast round Feb 2026
  16. 16Serious EnergySerious Energy, based in Sunnyvale, California, was founded in 2002 and specializes in manufacturing acoustical and thermal solutions for the built environment.

    Serious Energy, based in Sunnyvale, California, was founded in 2002 and specializes in manufacturing acoustical and thermal solutions for the built environment.

    Founded 2002Sunnyvale, United States$135Mlast round Nov 2011
  17. 17Terra CO2Founded -United States$125Mlast round Jul 2025
  18. 18KouraKoura is a global leader in the development, manufacture, and supply of fluoro products.

    Koura is a global leader in the development, manufacture, and supply of fluoro products.

    Founded 2011Waltham, United States$100Mlast round Oct 2022
  19. 19CambiumCambium is an advanced materials company based in California, specializing in high-performance materials for defense, aerospace, and dual-use applications.

    Cambium is an advanced materials company based in California, specializing in high-performance materials for defense, aerospace, and dual-use applications.

    Founded 2019El Segundo, United States$100Mlast round Jan 2025
  20. 20Mitra ChemMitra Chem is an AI-native manufacturer of lithium-ion battery materials, founded in 2021 and headquartered in Mountain View, California.

    Mitra Chem is an AI-native manufacturer of lithium-ion battery materials, founded in 2021 and headquartered in Mountain View, California.

    Founded 2021Mountain View, United States$91Mlast round Jun 2025
  21. 21Lehigh TechnologiesLehigh Technologies is a specialty materials company that manufactures high-performance, lower cost, sustainable micronized rubber powders.

    Lehigh Technologies is a specialty materials company that manufactures high-performance, lower cost, sustainable micronized rubber powders.

    Founded 2003Tucker, United States$88Mlast round Sept 2014
  22. 22MBA PolymersMBA Polymers produces post-consumer recycled plastics from end-of-life durable goods, like cars, computers, and household equipment.

    MBA Polymers produces post-consumer recycled plastics from end-of-life durable goods, like cars, computers, and household equipment.

    Founded 1994Hackensack, United States$86Mlast round Feb 2011
  23. 23Project FrogProject Frog is revolutionizing the building industry by applying technology to streamline design and construction processes.

    Project Frog is revolutionizing the building industry by applying technology to streamline design and construction processes.

    Founded 2006San Francisco, United States$63Mlast round Aug 2014
  24. 24NanoGraf CorporationNanoGraf is a battery development company researching ways to improve battery life and charging time.

    NanoGraf is a battery development company researching ways to improve battery life and charging time.

    Founded 2012Chicago, United States$60Mlast round Sept 2024
  25. 25EncinaENCINA, formally known as Encina Development Group, LLC, is a circular economy company founded in 2016 and based in The Woodlands, Texas.

    ENCINA, formally known as Encina Development Group, LLC, is a circular economy company founded in 2016 and based in The Woodlands, Texas.

    Founded 2016The Woodlands, United States$60Mlast round Aug 2023
  26. 26AlbertAlbert is a Los Angeles-based financial technology company founded in 2015.

    Albert is a Los Angeles-based financial technology company founded in 2015.

    Founded 2016Los Angeles, United States$57Mlast round Oct 2026
  27. 27Li IndustriesLi Industries is a climate tech company based in Pineville, North Carolina, founded in 2017.

    Li Industries is a climate tech company based in Pineville, North Carolina, founded in 2017.

    Founded 2017Pineville, United States$55Mlast round Sept 2024
  28. 28Radical AIRadical AI is a materials science company founded in 2024 and based in New York, New York.

    Radical AI is a materials science company founded in 2024 and based in New York, New York.

    Founded 2024New York, United States$55Mlast round Jul 2025
  29. 29CambridgeSoftCambridgeSoft is a software solutions supplier to the pharmaceutical, biotechnology, and chemical industries.

    CambridgeSoft is a software solutions supplier to the pharmaceutical, biotechnology, and chemical industries.

    Founded 1986Cambridge, United States$54Mlast round Nov 2009
  30. 30EpsilyteEpsilyte produces insulative materials used in construction, packaging, and safety equipment.

    Epsilyte produces insulative materials used in construction, packaging, and safety equipment.

    Founded 2015The Woodlands, United States$52Mlast round Aug 2023
  31. 31Princeton NuEnergyPrinceton NuEnergy is a clean-tech startup focused on direct recycling technology for lithium-ion batteries.

    Princeton NuEnergy is a clean-tech startup focused on direct recycling technology for lithium-ion batteries.

    Founded 2019Bordentown, United States$50Mlast round Aug 2026
  32. 32NovomerNovomer is a sustainable chemistry company developing high performance, environmentally responsible polymers and chemical intermediates.

    Novomer is a sustainable chemistry company developing high performance, environmentally responsible polymers and chemical intermediates.

    Founded 2004Rochester, United States$46Mlast round Dec 2013
  33. 33LydianLydian aims to accelerate the decarbonization of the chemical industry by electrifying the chemical production process.

    Lydian aims to accelerate the decarbonization of the chemical industry by electrifying the chemical production process.

    Founded 2021Salem, United States$44Mlast round Jan 2026
  34. 34MIOXMIOX develops on-site chemical generators and sustainable treatment technologies for water disinfection.

    MIOX develops on-site chemical generators and sustainable treatment technologies for water disinfection.

    Founded 1994Albuquerque, United States$43Mlast round Oct 2015
  35. 35IntematixIntematix Corporation develops and manufactures phosphor products to light and imaging markets.

    Intematix Corporation develops and manufactures phosphor products to light and imaging markets.

    Founded 2000Fremont, United States$41Mlast round Mar 2012
  36. 36MstackServices Lines Cloud Computing Engineering Infrastructure Management Infrastructure Outsourcing Application Management Application Outsourcing Management Consul

    Services Lines Cloud Computing Engineering Infrastructure Management Infrastructure Outsourcing Application Management Application Outsourcing Management Consul

    Founded 2015St. Petersburg, United States$40Mlast round Oct 2024
  37. 37BlueOak ResourcesBlueOak Resources is a clean-tech company based in the U.S.

    BlueOak Resources is a clean-tech company based in the U.S.

    Founded 2011Burlingame, United States$36Mlast round Jun 2014
  38. 38LithiosLithios is a technology company that uses electrochemistry for advanced lithium extraction from tough mixtures.

    Lithios is a technology company that uses electrochemistry for advanced lithium extraction from tough mixtures.

    Founded 2022Medford, United States$35Mlast round Nov 2026
  39. 39Leyden EnergyLeyden Energy is a California-based manufacturer specializing in advanced Li-imide batteries, which are designed for mobile devices, consumer electronics, energ

    Leyden Energy is a California-based manufacturer specializing in advanced Li-imide batteries, which are designed for mobile devices, consumer electronics, energ

    Founded 2007Fremont, United States$35Mlast round Jan 2013
  40. 40Citrine InformaticsCitrine Informatics provides an informatics platform that transforms chemicals development through AI embedded in smart data infrastructure.

    Citrine Informatics provides an informatics platform that transforms chemicals development through AI embedded in smart data infrastructure.

    Founded 2013Redwood City, United States$33Mlast round Sept 2023
  41. 41iRocketiRocket offers content writing, SEO optimization, IT, marketing services, and develops reusable rocket technology.

    iRocket offers content writing, SEO optimization, IT, marketing services, and develops reusable rocket technology.

    Founded 2023United States$33Mlast round Jun 2022
  42. 42SegetisSegetis is the main levulinic acid derivatives producer in the US with very valuable proprietary technologies in the fragrances, plasticizers PVC & biopolymers,

    Segetis is the main levulinic acid derivatives producer in the US with very valuable proprietary technologies in the fragrances, plasticizers PVC & biopolymers,

    Founded 2006Golden Valley, United States$32Mlast round Dec 2009
  43. 43Access VascularFounded -United States$32Mlast round Oct 2023
  44. 44Prometheus HyperscalePrometheus Hyperscale is a data center developer founded in 2024, focusing on sustainable, liquid-cooled hyperscale infrastructure.

    Prometheus Hyperscale is a data center developer founded in 2024, focusing on sustainable, liquid-cooled hyperscale infrastructure.

    Founded 2024Houston, United States$30Mlast round Sept 2026
  45. 45NanoTech MaterialsNanoTech Materials, Inc.

    NanoTech Materials, Inc.

    Founded 2019Houston, United States$29Mlast round Apr 2026
  46. 46Cyalume TechnologiesCyalume Technologies designs, develops, and produces reliable chemical and electronic lights for safety and security applications.

    Cyalume Technologies designs, develops, and produces reliable chemical and electronic lights for safety and security applications.

    Founded 1997United States$29Mlast round May 2015
  47. 47UbiQDUbiQD is an advanced materials company that manufactures low-hazard quantum dots (QDs) and nanocomposites.

    UbiQD is an advanced materials company that manufactures low-hazard quantum dots (QDs) and nanocomposites.

    Founded 2014Los Alamos, United States$28Mlast round Jan 2026
  48. 48SpectraSensorsSpectraSensors manufactures and supplies precision optical laser-based gas analyzers for the energy and petrochemical industries.

    SpectraSensors manufactures and supplies precision optical laser-based gas analyzers for the energy and petrochemical industries.

    Founded 1999United States$28Mlast round May 2009
  49. 49Xenon ArcXenon arc is a data-driven marketing and sales company founded in 2010 and based in Bellevue, Washington.

    Xenon arc is a data-driven marketing and sales company founded in 2010 and based in Bellevue, Washington.

    Founded 2010Bellevue, United States$28Mlast round Jun 2012
  50. 50Solidia TechnologiesSolidia Technologies is a tech firm that makes it profitable to use CO2 for manufacturing construction and industrial products.

    Solidia Technologies is a tech firm that makes it profitable to use CO2 for manufacturing construction and industrial products.

    Founded 2008San Antonio, United States$27Mlast round Dec 2014
Total fundinghow the list is ranked
15 November 2026updated nightly
Rounds we tracksource: Millionrounds

Companies whose funding rounds we classed as this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

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